ch 18
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| epi | can be admin subQ, IV, topically, inhalation, intracardiac
it is not given orally because it is rapidly metabolized by the liver and excreted in urine
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| epi | used in emergencies
treats anaphylaxis
potent inotropic - ↑contractility, promotes vasoconstriction, and CO
high doses can result in dysrhythmias - must be on ECG monitor
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| epi and digoxin | dysrhythmia
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| epi and beta blockers | antagonizes the action of epi
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| epi and MAOIs | make epi's effects intensified and prolonged
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| antedote for extravasation of norepi and dopamine | ☺phentolamine mesylate (regitine), 5-10 mg diluted in 10-15 mL of saline infiltrated into area for IV extravasation
☻redness and tissue warmth are signs of effective treatment
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| atenolol and metropolol | ☺selective
☻↓BP and pulse
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| atenolol (Tenornmin) | ☺selective beta blocker
☻CI in bradycardia, heart block, cardiogenic shock, pulm edema, acute bronchospasm, and pregnancy
♥once per day dosing
♦PO: onset 1 hr, peak 2-4 hrs, duration 24
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| doxazosin (Cardura) | alpha1-adrenergic blocker
☺treats HTN and BPH
☻s/e: dizziness, HA, syncope
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| atenolol (Tenormin) | beta1-adrenergic blocker
☺HTN, angina, dysrhythmia
☻check apical pulse
♥do not give if HR <60
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| atenolol Prototype Drug | ☺beta1-adrenergic blocker
☻CI: bradycardia, heart block >1st degree, cardiogenic shock, pulm edema, acute bronchospasm, uncompensated cardiac failure, pregnancy, lactation
♥used to tx angina, HTN, MI, HF,
♣s/e: drowsiness, dizziness, syncope, depression, alopecia, weakness, n/v/d, cool extremities, impotence, ↓libido
a/e: bradycarida, HoTN, HF, masking of hypoglycemia, bronchospasm, pulm edema, dysrhythmias, thrombocytopenia
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Created by:
nursingTSJC2013
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