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Top 200 grp 2

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Brand
Generic
Class
Indication
Dose Form
Route
Adult Dose
Pediatric Dose
MOA
Aciphex   Rabeprazole   PPI (proton pump inhibitor)   GERD, Duodenal Ulcer Disease   Tablet: 20 mg   Oral   20-60 mg QD-BID   show Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells  
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Nexium   esomeprazole   PPI (proton pump inhibitor)   GERD, Duodenal Ulcer Disease, Gastric Ulcer   Delayed-release caps: 20 or 40 mg Delayed-release powder for susp: 2.5, 5, 10, 20, 40 mg Powder for inj: 20 or 40 mg   Oral, injection   20-40 mg QD   1 MO -1 YO: 0.5mg/kg QD 1-17 YO: 10-20 mg QD for 8 weeks   show
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Prevacid   lansoprazole   PPI (proton pump inhibitor)   show Tablets or Solutabs: 15-30 mg   Oral   15-30 mg QD   1-12YO: <30kg15mg;>30kg 30mg QD   Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells  
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Prilosec   show PPI (proton pump inhibitor)   GERD, Duodenal Ulcer Disease, Stress Ulcer, Gastric Ulcer, Esophagitis   Delayed-release Granules for susp: 2.5 or 10 mg Delayed-release Caps: 10, 20, 40 mg Delayed-release OTC Tab: 20 mg   Oral   20-40 mg QD   5-20 mg QD   Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells  
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show pantoprazole   PPI (proton pump inhibitor)   GERD, Gastric Hypersecretion   Delayed-release Tab: 20-40 mg Delayed-release granules for susp: 40 mg Powder for Inj: 40 mg   Oral, IV   40-80 mg QD-BID   >5YO:<40kg-20mg; >40kg-40mg QD   Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells  
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Dexilant   dexlansoprazole   PPI (proton pump inhibitor)   Esophagitis, GERD, Pyrosis (heartburn)   Delayed-relase capsule: 30 or 60 mg   Oral   30-60 mg QD   N/A   show
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Welchol   Colesevelam   Bile Acid Sequesterant   Hypercholesterolemia, Hyperlipoproteinemia, Type 2 Diabetes Mellitus   Tablet: 625mg Powder for Susp: 3.75mg   Oral   3 tabs BID or 6 tabs QD; 1.875 gram packet BID or 3.75 gram packet QD   10-17 YO: 1.875 gram single-dose packet BID or 3.75 gram packet QD (Not for under 10 yrs)   show
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Zantac   Ranitidine   Histamine, H2 antagonist   GERD, Duodenal Ulcer Disease, Gastric Ulcer, Indigestion   Syrup: 75mg/5ml or 150mg/10ml Tablets: 75, 150, 300mg Inj. Soln.: 1mg/ml or 25mg/ml Granules for Soln.: 150mg Effervescent Tab: 25 or 150mg   show Oral: 150mg QD-BID IV: 50mg Q6-8 hrs   2-4 mg/kg/day (oral or IV)   Competitive reversible inhibitor of histamine at H2 receptors  
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Zetia   Ezetimibe   Cholesterol Absorption Inhibitor   Hypercholesterolemia, Hyperlipoproteinemia   show Oral   10mg QD   10 YO+: 10mg QD   Inhibits absorption of cholesterol at the brush border of the small intestine via the sterol transporter NPC1L1  
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Niaspan   Niacin   Nicotinic Acid   Hyperlipidemia   show Oral   100-1000mg TID (max of 4500mg/day)   100-250mg QD (divided into 3 doses)   Precise MOA unknown  
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Pepcid   Famotidine   Histamine H2 Antagonist   show Tablets: 20 or 40mg; AC 10mg tablet or gelcap Premixed Inj. Soln.: 10mg/ml, 20mg/50ml Powder For Susp: 40mg/5ml Complete Chew Tab   Oral, IV   20-160mg QD or BID   0-16YO: 0.5mg/kg QD or BID   Inhibits the binding of histamine to H2 receptors on the gastric basolateral membrane of parietal cells, reducing basal and nocturnal gastric acid secretions  
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Tricor   Fenofibrate   show Hypercholesterolemia, hypertriglyceridema   Tablet: 48mg, 145mg   Oral   Hypertriglyceridemia: 48-145mg QD Hypercholesterolemia or mixed dysplipidemia: 145mg QD   safety not established   Agonist of nuclear transcription factor PPar-alpha  
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show Ezetimibe/Simvastatin   Antilipemic Agent, HMG-CoA Reductase Inhibitor   Hypercholesterolemia, Hyperlipidemia, ASCVD   Tablet: 10mg, 20mg, 40mg, 80mg   Oral   10-40 mg po qd   10yrs+ 10-20 mg po qd   sterol transporter inhibitor, HMG-CoA Reductase inhibitor  
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Lipitor   Atorvastatin   HMG-CoA Reductase Inhibitor   Hypercholeserolemia & mixed hyperlipidemia, ASCVD   Tablet: 10mg, 20mg, 40mg, 80mg   Oral   10-80 mg qd   HeHF: 10-17yr(females>1 yr postmenarche): 10mg qd. Max 20mg   show
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Lovaza   Omega-3 ethyl esters   Acyl-CoA Inhibitor   Hypertriglyceridemia   Soft gel Capsule: 1g=1000mg   Oral   4g qd or 2g bid   N/A   show
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Mevacor   Lovastatin   Antilipemic agent, HMG-CoA Reductase Inhibitor   Dyslipidemia & 1o prevent of CAD (coronary artery disease), ASCVD   Tablet: 10, 20, 40mg   show 20mg qd w/ evening meal. Max 80mg ASCVD: 40mg qd   Heterozygous familial hypercholesterolemia: 10-17yr LDL reduction <20%: 10 qd w/ evening meal LDL reduction ≥ 20%: 20 qd w/ evening meal Max: 40 mg   HMG-CoA Reductase Inhibitor  
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Crestor   Rosuvastatin   HMG-CoA Inhibitor   show Tablets:5,10,20,40 mg   oral   5-40mg QD   10-17YO:5-20mg QD   HMG-CoA Reductase inhibitor  
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Pravachol   Pravastatin   HMG-CoA Inhibitor   Hyperlipidemia, Hypercholesterolemia, Prophylaxis   show oral   40-80mgQD   8-13YO:20 mg QD 13-18YO: 40mg QD   HMG-CoA Reductase inhibitor  
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Trilipix   Choline Fenofibrate   Antilipemic Agent, Fibric Acid   Hypercholesterolemia, hypertriglyceridema   show Oral   Hypertriglyceridemia: 45-135mg QD Hypercholesterolemia or mixed dysplipidemia: 135mg QD   Safety and efficacy in children have not been established   Agonist of nuclear transcription factor PPar-alpha  
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Antara   Fenofibrate   show Hypercholesterolemia, hypertriglyceridema   Capsule: 30,90 mg   Oral   Hypertriglyceridemia: 30-90mg QD Hypercholesterolemia or mixed dysplipidemia: 90mg QD   Safety and efficacy in children have not been established   Agonist of nuclear transcription factor PPar-alpha  
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Zocor   Simvastatin   HMG-CoA Inhibitor   show Tablet: 5,10,20,40,80mg   Oral   Hyperlipidemia: 5 to 40 mg QD in the evening. Homozygous familial hypercholesterolemia: 40 mg QD in the evening, Prevention of coronary events: 5 to 40 mg QD in the evening   Heterozygous familial hypercholesterolemia: 10 to 17 years of age: 10 to 40 mg QD   HMG-CoA Reductase inhibitor  
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Zofran   Ondansetron   show Prevention of nausea and vomiting due to chemo, or post op, or radiotherapy   Tablet Dispersible: 4,8mg Film: 4,8mg   Oral   Cancer,Highly Emetogenic: 24mg 30min before, Moderate Emetogenic: 8mg Bid start 30 before. Radiotherapy: 8mg TID start 1-2 before. Post op: 16mg 1hr prior to anesthesia   Only approved for moderately emetogenic <12 years of age: 8mg BID start 30 min before. 4-11 years of age: 8mg BID start 30 min before.   Serotonin Receptor Antagonist, 5-HT3 (Antiemetic)  
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