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P1, top 200, grp 2

Top 200 grp 2

BrandGenericClassIndicationDose FormRouteAdult DosePediatric DoseMOA
Aciphex Rabeprazole PPI (proton pump inhibitor) GERD, Duodenal Ulcer Disease Tablet: 20 mg Oral 20-60 mg QD-BID 12 years and older: 20 mg once daily for 8 weeks.1 1 to 11 years: 15 kg or more: 10 mg once daily for up to 12 weeks. Less than 15 kg: 5 mg once daily for up to 12 weeks; increase to 10 mg if inadequate response Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Nexium esomeprazole PPI (proton pump inhibitor) GERD, Duodenal Ulcer Disease, Gastric Ulcer Delayed-release caps: 20 or 40 mg Delayed-release powder for susp: 2.5, 5, 10, 20, 40 mg Powder for inj: 20 or 40 mg Oral, injection 20-40 mg QD 1 MO -1 YO: 0.5mg/kg QD 1-17 YO: 10-20 mg QD for 8 weeks Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Prevacid lansoprazole PPI (proton pump inhibitor) Duodenal Ulcer Disease, Gastric ULcer, Esophagitis, GERD Tablets or Solutabs: 15-30 mg Oral 15-30 mg QD 1-12YO: <30kg15mg;>30kg 30mg QD Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Prilosec omeprazole PPI (proton pump inhibitor) GERD, Duodenal Ulcer Disease, Stress Ulcer, Gastric Ulcer, Esophagitis Delayed-release Granules for susp: 2.5 or 10 mg Delayed-release Caps: 10, 20, 40 mg Delayed-release OTC Tab: 20 mg Oral 20-40 mg QD 5-20 mg QD Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Protonix pantoprazole PPI (proton pump inhibitor) GERD, Gastric Hypersecretion Delayed-release Tab: 20-40 mg Delayed-release granules for susp: 40 mg Powder for Inj: 40 mg Oral, IV 40-80 mg QD-BID >5YO:<40kg-20mg; >40kg-40mg QD Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Dexilant dexlansoprazole PPI (proton pump inhibitor) Esophagitis, GERD, Pyrosis (heartburn) Delayed-relase capsule: 30 or 60 mg Oral 30-60 mg QD N/A Suppresses gastric secrecion by inhibiting the gastric H+, K+ ATPase at the secretory surface of parietal cells
Welchol Colesevelam Bile Acid Sequesterant Hypercholesterolemia, Hyperlipoproteinemia, Type 2 Diabetes Mellitus Tablet: 625mg Powder for Susp: 3.75mg Oral 3 tabs BID or 6 tabs QD; 1.875 gram packet BID or 3.75 gram packet QD 10-17 YO: 1.875 gram single-dose packet BID or 3.75 gram packet QD (Not for under 10 yrs) Binds with bile acids in the intestine to form an insoluble complex that is eliminated in the feces
Zantac Ranitidine Histamine, H2 antagonist GERD, Duodenal Ulcer Disease, Gastric Ulcer, Indigestion Syrup: 75mg/5ml or 150mg/10ml Tablets: 75, 150, 300mg Inj. Soln.: 1mg/ml or 25mg/ml Granules for Soln.: 150mg Effervescent Tab: 25 or 150mg Oral, IV Oral: 150mg QD-BID IV: 50mg Q6-8 hrs 2-4 mg/kg/day (oral or IV) Competitive reversible inhibitor of histamine at H2 receptors
Zetia Ezetimibe Cholesterol Absorption Inhibitor Hypercholesterolemia, Hyperlipoproteinemia Tablets: 10mg Oral 10mg QD 10 YO+: 10mg QD Inhibits absorption of cholesterol at the brush border of the small intestine via the sterol transporter NPC1L1
Niaspan Niacin Nicotinic Acid Hyperlipidemia ER Tablets: 500, 750, 1000mg Oral 100-1000mg TID (max of 4500mg/day) 100-250mg QD (divided into 3 doses) Precise MOA unknown
Pepcid Famotidine Histamine H2 Antagonist Duodenal Ulcer, Dyspepsia, Esophagitis, Gastric Ulcer, GERD, H. Pylori Eradication, Multiple Endocrine Adenoma Syndrome, Pyrosis, Systemic Mastocytosis, Zollinger-Ellison Syndrome Tablets: 20 or 40mg; AC 10mg tablet or gelcap Premixed Inj. Soln.: 10mg/ml, 20mg/50ml Powder For Susp: 40mg/5ml Complete Chew Tab Oral, IV 20-160mg QD or BID 0-16YO: 0.5mg/kg QD or BID Inhibits the binding of histamine to H2 receptors on the gastric basolateral membrane of parietal cells, reducing basal and nocturnal gastric acid secretions
Tricor Fenofibrate Antilipemic Agent, Fibric Acid Hypercholesterolemia, hypertriglyceridema Tablet: 48mg, 145mg Oral Hypertriglyceridemia: 48-145mg QD Hypercholesterolemia or mixed dysplipidemia: 145mg QD safety not established Agonist of nuclear transcription factor PPar-alpha
Vytorin Ezetimibe/Simvastatin Antilipemic Agent, HMG-CoA Reductase Inhibitor Hypercholesterolemia, Hyperlipidemia, ASCVD Tablet: 10mg, 20mg, 40mg, 80mg Oral 10-40 mg po qd 10yrs+ 10-20 mg po qd sterol transporter inhibitor, HMG-CoA Reductase inhibitor
Lipitor Atorvastatin HMG-CoA Reductase Inhibitor Hypercholeserolemia & mixed hyperlipidemia, ASCVD Tablet: 10mg, 20mg, 40mg, 80mg Oral 10-80 mg qd HeHF: 10-17yr(females>1 yr postmenarche): 10mg qd. Max 20mg HMG-CoA Reductase inhibitor
Lovaza Omega-3 ethyl esters Acyl-CoA Inhibitor Hypertriglyceridemia Soft gel Capsule: 1g=1000mg Oral 4g qd or 2g bid N/A Acyl-CoA Inhibitor
Mevacor Lovastatin Antilipemic agent, HMG-CoA Reductase Inhibitor Dyslipidemia & 1o prevent of CAD (coronary artery disease), ASCVD Tablet: 10, 20, 40mg Oral 20mg qd w/ evening meal. Max 80mg ASCVD: 40mg qd Heterozygous familial hypercholesterolemia: 10-17yr LDL reduction <20%: 10 qd w/ evening meal LDL reduction ≥ 20%: 20 qd w/ evening meal Max: 40 mg HMG-CoA Reductase Inhibitor
Crestor Rosuvastatin HMG-CoA Inhibitor Hyperlipidemia,Hypertriglyceridemia, Atherosclerosis,Hyperlipoproeteinemia,Hypercholesterolemia,Prophylaxis Tablets:5,10,20,40 mg oral 5-40mg QD 10-17YO:5-20mg QD HMG-CoA Reductase inhibitor
Pravachol Pravastatin HMG-CoA Inhibitor Hyperlipidemia, Hypercholesterolemia, Prophylaxis Tablets: 10,20,40,80 oral 40-80mgQD 8-13YO:20 mg QD 13-18YO: 40mg QD HMG-CoA Reductase inhibitor
Trilipix Choline Fenofibrate Antilipemic Agent, Fibric Acid Hypercholesterolemia, hypertriglyceridema Capsule Delayed release 45mg and 135mg Oral Hypertriglyceridemia: 45-135mg QD Hypercholesterolemia or mixed dysplipidemia: 135mg QD Safety and efficacy in children have not been established Agonist of nuclear transcription factor PPar-alpha
Antara Fenofibrate Antilipemic Agent, Fibric Acid Hypercholesterolemia, hypertriglyceridema Capsule: 30,90 mg Oral Hypertriglyceridemia: 30-90mg QD Hypercholesterolemia or mixed dysplipidemia: 90mg QD Safety and efficacy in children have not been established Agonist of nuclear transcription factor PPar-alpha
Zocor Simvastatin HMG-CoA Inhibitor Heterozygous familial hypercholesterolemia in adolescents (10 to 17 years of age, Hyperlipidemia, Primary and secondary prevention of atherosclerotic cardiovascular disease Tablet: 5,10,20,40,80mg Oral Hyperlipidemia: 5 to 40 mg QD in the evening. Homozygous familial hypercholesterolemia: 40 mg QD in the evening, Prevention of coronary events: 5 to 40 mg QD in the evening Heterozygous familial hypercholesterolemia: 10 to 17 years of age: 10 to 40 mg QD HMG-CoA Reductase inhibitor
Zofran Ondansetron Serotonin Receptor Antagonist, 5-HT3 (Antiemetic) Prevention of nausea and vomiting due to chemo, or post op, or radiotherapy Tablet Dispersible: 4,8mg Film: 4,8mg Oral Cancer,Highly Emetogenic: 24mg 30min before, Moderate Emetogenic: 8mg Bid start 30 before. Radiotherapy: 8mg TID start 1-2 before. Post op: 16mg 1hr prior to anesthesia Only approved for moderately emetogenic <12 years of age: 8mg BID start 30 min before. 4-11 years of age: 8mg BID start 30 min before. Serotonin Receptor Antagonist, 5-HT3 (Antiemetic)
Created by: Ryan Stocks