MOA of drugs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Competitive blockers (SM Relaxants) | Prevent ACh from binding to the NMJ and prevent depolarisation
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| Persistent depolarisers (SM Relaxants) | ACh analogues binding to NMJ and depolarise for a longer time
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| DIRECTLY ACTING MUSCLE RELAXANTS | PREVENT CALCIUM ION CHANNEL
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| MEPHENESIN | INHIBIT POLYSYNAPTIC REFLEXES
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| BENZODIAZEPINE | INCREASE GABA CHANNELS
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| GABA DERIVATIVE | INCREASES GABA ACTION
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| CENTRAL ALPHA-2 AGONIST | PRESYNAPTIC INHIBITION WHICH INHIBITS RELEASE OF EXCITATORY AMINO ACIDS
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| QUININE | DECREASES THE EXCITABILITY OF THE NMJ
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| BOTULINUM | PREVENTS CALCIUM DEPENDENT ACh RELEASE
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| LOCAL ANAESTHETICS | BLOCK Na CHANNELS
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| THIAZIDE DIURETICS | REDUCE REABSORPTION OF Na AND WATER IN THE PROXIMAL PART OF DISTAL TUBULE
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| LOOP DIURETICS | REDUCE REABSORPTION IN LIMB OF LOOP OF HENLE
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| POTASSIUM SPARING DIURETICS | REDUCE REABSORPTION OF Na AT THE DISTAL PART OF THE DISTAL TUBULE AND ALSO REDUCE K EXCRETION
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| ALDOSTERONE RECEPTOR ANTAG | REDUCE ALDOSTERONE IN ORDER TO PREVENT Na AND WATER REABSORPTION IN DT AND CT
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| OSMOTIC DIURETICS | INCREASE THE OSMOLARITY OF THE FILTRATE AND INCREASES THE FILTRATION LOAD AND REDUCES REABSORPTION . DUE TO HIGH OSMOTIC PRESSURE ADH IS ALSO INEFFECTIVE
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| CA INHIBITORS | PREVENT THE ENZYME FEOM ACTING AND HENCE PREVENT Na AND WATER REABSORPTION
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| XANTHINES | DILATES AFFERENT ARTERIOLES and prevents reabsorption of water and Na
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| VASOPRESSIN | INCREASES REABSORPTION OF Na AND WATER
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| HYDRALAZINE | INCREASES NITRIC OXIDE AND K CHANNELS TO CAUSE VASODILATION
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| MINOXIDIL | K CHANNEL OPENER
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| BUMETANIDE | BLOCKS REABSORPTION OF SODIUM AND WATER IN THE ASCENDING LIMB OF LOOP OF HENLE
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| CARVEDILOL | ALPHA 1 AND BETA 1 , 2 BLOCKER ; VENTRICULAR FAILURE
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| PRAVASTATIN | HMG CoA REDUCTASE INHIBITOR
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| CHOLESTYRAMINE | BILE ACID BINDING RESINS; USED IN HYPERCHOLESTEROLEMIA
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| COLESTIPOL | BILE ACID BINDING RESINS; USED IN HYPERCHOLESTEROLEMIA
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| COLESELVAM | BILE ACID BINDING RESINS; USED IN HYPERCHOLESTEROLEMIA
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| EZETIMIBE | INHIBITS INTESTINAL ABSORPTION OF CHOLESTEROL
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| GEMFIBROZIL | LpL ACTIVATORS
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| FENOFIBRATE | LpL ACTIVATORS
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| BEZAFIBRATE | LpL ACTIVATORS
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| NIACIN / NICOTINIC ACID | INHIBITS APO B CONTAINING LIPOPROTEINS
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| DIMENHYDRINATE | ANTI HISTAMINIC (I) ; ANTI MOTION
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| DIPHENHYDRAMINE | ANTI HISTAMINIC (I) ; ANTI MOTION SICKNESS , ANTI PARKINSONS , LOCAL ANAESTHETIC
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| DOXYLAMINE | ANTI HISTAMINIC (I) ; SLEEP AID
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| HYDROXYZINE | ANTI HISTAMINIC (I) ; ANTI EMETIC
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| PROMETHAZINE | ANTI HISTAMINIC (I); ANTI EMETIC , ANTI PARKINSON , LA
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| CYCLIZINE | ANTI HISTAMINIC (I); ANTI MOTION
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| MECLIZINE | ANTI HISTAMINIC (I) ; anti motion
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| FEXOFENADINE | ANTI HISTAMINIC (II) ; ANTI INFLAMMATORY
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| CETIRIZINE | ANTI HISTAMINIC (II) ;
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| LEVOCETIRIZINE | ANTI HISTAMINIC (II) ;
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| DESLORATIDINE | ANTI HISTAMINIC (II) ; ANTI INFLAMMATORY
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| LORATADINE | ANTI HISTAMINIC (II) ;
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| CIMETIDINE | ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
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| RANITIDINE | ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
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| FAMOTIDINE | ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
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| NIZATIDINE | ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
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| CROMOLYN SODIUM | HISTAMINE RELEASE INHIBITORS ; ASTHMA , RHINITIS
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| NEDOCROMOLYN SODIUM | HISTAMINE RELEASE INHIBITORS ; ASTHMA , RHINITIS
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| KETOTIFEN | ANTI H1 WITH MAST CELL STABILISING ACTION
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| BUSPIRONE | 5 HT AGONISTS ; ANTI ANXIETY
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| SUMATRIPTAN | 5HT1B , 5HT1C AGONIST , ANTI MIGRAINE
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| CISAPRIDE | 5HT4 AGONISTS , GASTROESOPHAGEAL REFLUX
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| RENZAPRIDE | 5HT4 AGONISTS , GASTROESOPHAGEAL REFLUX
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| TEGASEROD | 5HT4 PARTIAL AGONIST , IRRITABLE BOWEL SYNDROME
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| DEXFENFLURAMINE | NON SELECTIVE 5HT RECEPTOR AGONIST , SPPETITE SUPRESSANT
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| LSD | NON SELECTIVE 5HT AGONIST ; HALLUCINOGEN
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| KETANSERIN | 5HT2A ANTAG , ANTI HYPERTENSIVE , RAYNAUDS DISEASE
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| RITANSERIN | 5HT2A ANTAG
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| ONDANSETRON | 5HT3 ANTAG , POST OP ANTIEMETIC , CHEMOTHERAPY INDUCED ALSO
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| DOLASETRON | 5HT3 ANTAG , POST OP ANTIEMETIC
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| GRANISETRON | 5HT3 ANTAG , POST OP ANTIEMETIC
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| CLOZAPINE | 5HT AND DOPAMINE ANTAG , ANTIPSYCHOTIC
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| OLANZAPINE | 5HT AND DOPAMINE ANTAG , ANTIPSYCHOTIC
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| RISPERIDONE | 5HT AND DOPAMINE ANTAG , ANTIPSYCHOTIC
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| METHYLSERGIDE | 5HT 2A ANTAG ; USED IN MIGRAINE PROPHYLAXIS
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| CYPROHEPTADINE | 5HT 2A ANTAG , POSTGASTRECTOMY AND CARCINOID
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| ERGOTAMINE | PARTIAL AGONIST 5HT ,
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| BROMOCRIPTINE | PARTIAL AGONIST 5HT , PARKINSON
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| ERGOMETRINE | PARTIAL AGONIST 5HT , PREVENT POST PARTUM HAEMORRHAGE
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| DINOPROSTONE | PGE2 ; INDUCING ABORTION , LABOUR AND POST PARTUM HAEMORRHAGE PREVENTION
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| MISOPROSTOL | PGE2 ; ABORTIFACIENT , PEPTIC ULCER
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| CARBOPROST | PGF2ALPHA , ABORTIFACIENT , LABOUR AND POST PARTUM HAEMORRHAGE PREVENTION
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| ENPROSTIL | PGE2 , PEPTIC ULCER
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| EPOPROSTENOL | PGI2 , PREVENT PLATELET AGGREG , DUCTUS ARTERIOSUS , PULMONARY HYPERTENSION
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| LATANOPROST | PGF2 ALPHA , USED IN GLAUCOMA
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| ALPROSTADIL | PGE1 , NALE IMPOTENCE
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| ZAFIRLUKAST | cys LT RECEPTOR ANTAG
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| MONTELEUKAST | cys LT RECEPTOR ANTAG
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| IRALUKAST | cys LT RECEPTOR ANTAG
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| ZILEUTON | LIPOOXYGENASE INHIBITOR ; ANTI ASTHMA AND ANTIINFLAMMATORY
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| SULFASALAZINE | NONSELECTIVE IRREVERSIBLE OF COX , ULCERATIVE COLITIS , ARTHRITIS
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| SODIUM SALICYLATE | NONSELECTIVE IRREVERSIBLE OF COX
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| METHYL SALICYLATE | NONSELECTIVE IRREVERSIBLE OF COX
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| PHENYLBUTAZONE | NON SELECTIVE REVERSIBLE COX
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| OXYPHENBUTAZONE | NON SELECTIVE REVERSIBLE COX
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| IBUPROFEN | NON SELECTIVE REVERSIBLE COX
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| KETOPROFEN | NON SELECTIVE REVERSIBLE COX
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| MEFENAMIC ACID | NON SELECTIVE REVERSIBLE COX , DYEMENNORHOEA , OSTEOARTHRITIS
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| FLUFENAMIC ACID | NON SELECTIVE REVERSIBLE COX
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| PIROXICAM | NON SELECTIVE REVERSIBLE COX , ACUTE GOUT
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| KETOROLAC | NON SELECTIVE REVERSIBLE COX , CONJUNCTIVITIS
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| DICLOFENAC | NON SELECTIVE REVERSIBLE COX
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| NIMESULIDE | WEAK INHIB OF COX1 AND COX2
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| ETODOLAC | PREFERENTIAL COX2
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| ROFECOXIB | SELECTIVE COX2
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| VAKDECOXIB | SELECTIVE COX2
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| PARACETAMOL | COX3 OR REVERSIBLE OF COX1
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| NEFOPAM | NO INHIBITION OF PGs
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| ASPIRIN | NON SLEECTIVE IRREVERSIBLE OF COX , DUCTUS ARTERIOSUS CLOSURE , PRE ECCLAMPSIA , COLON AND RECTAL CANCER , ALZHEIMERS , FAMILIAL COLONIC POLYPOSIS , SLOWDOWN CATARACT
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| SALICYLIC ACID | NON SELECTIVE IRREVERSIBLE COX INHIB , KERATOLYTIC
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| INDOMETHACIN | NON SELECTIVE REVERSIBLE COX INHIB
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| COLCHICINE | INHIBITS NEUTROPHIL MIGRATION INTO THE JOINTS ; ACUTE GOUT
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| PREDNISOLONE | SUPRESSES INFLAMMATION ; ACUTE GOUT
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| ALLOPURINOL | INHIBITS XANTHINE OXIDASE , SO URIC ACID ; CHRONIC GOUT
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| PROBENECID | PROMOTES EXCRETION OF URIC ACID ; CHRONIC GOUT
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| SULFINPYRAZONE | PREVENTS REABSORPTION OF URIC ACID
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| INFLIXIMAB | INHIBITS T CELL AND MACROPHAGE
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| LEFLUNOMIDE | INHIBITS T CELL AND ANTIBODY PRODUCTION ; IMMUNOMODULATOR
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| METHOTREXATE | FOLIC ACID ANTAG ; IMMUNOMODULATOR
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| CYCLOSPORINE | INHIBITS IL1 AND IL2 RECEPTORS ; INHIBITS T CELL INTERACTION AND RESPONSIVENESS
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| AZATHIOPRINE | PRO DRUG OF 6 MERCAPTOPURINE MAKES A NON FUNCTIONAL NA WHICH IS INCORPORATED INTO DNA AND IS NON FUNCTIONAL ; INHIBITS T CELLS ; USED IN GRAFT TRANSPLANT
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| AURANOFIN | ALTERS MORPHOLOGY OF MACROPHAES AND PREVENTS JOINT DESTRUCTION
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| HYDROXYCHLOROQUINE | SUPRESS T CELL FUNCTION ; RA
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| SULFASALAZINE | ORAL , NON ABSORBABLE .IT IS METABOLISED TO SULFAPYRIDINE AND 5 ASA ; SULFAPYRIDINE MIGRATES TO JOINTS AND USED , WHILE 5 ASA IS USED IN RA
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| CYCLOPHOSPHAMIDE | CROSS LINKS DNA TO PREVENT CELL REPLICATION ; CANCER AND RA AS IMMUNOSUPRESSANT
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| SUCRALFATE | POLYMERISES BY CROSS LINKING OF MOLECULES TO FORM A GEL OVER THE ULCER
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| COLLOIDAL BISMUTH SUBCITRATE | IT CONVERTS INTO BISMUTH OXYCHLORIDE AND THEN CHELATES WITH GLYCOPROTEINS TO FORM A GEL OVER THE ULCER
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| PANTOPRAZOLE | BLOCKS H+/K+/ATPase AND PREVENTS FORMATION OF ACID
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| OMEPRAZOLE | BLOCKS H+/K+/ATPase AND PREVENTS FORMATION OF ACID
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| ESOMEPRAZOLE | BLOCKS H+/K+/ATPase AND PREVENTS FORMATION OF ACID
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| SODIUM ALGINATE | FORMS A GEL WITH THE ACID
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| SODIUM BICARBONATE | SYSTEMIC ANTACID , barb poisoning
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| ALUMINIUM HYDROXIDE | NON SYSTEMIC BUFFER ANTACID
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| MAGNESIUM TRISILICATE | NON SYSTEMIC BUFFER ANTACID
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| CALCIUM CARBONATE | NON SYSTEMIC NON BUFFER ANTACID
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| MAGNESIUM HYDROXIDE | NON SYSTEMIC NON BUFFER ANTACID
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| CARBENOXOLONE SODIUM | INCREASES PRODUCTION OF MUCUS
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| CLARITHROMYCIN | BLOCKS 50S RIBOSOMES ; ANTI HELICOBACTER
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| AMOXICILLIN | PENICILLIN GRP ; ANTI HELICOBACTER
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| METRONIDAZOLE | ANAEROBIC ; ANTI HELICOBACTER
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| CINNARIZINE | ANTI HISTAMINIC , CALCIUM BLOCKER ; MOTION SICKNESS
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| PROCHLORPERAZINE | 5HT3 ANTAG AND D2 BLOCKING ANTAGS ; CHEMO INDUCED VOMITING
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| METOCLOPRAMIDE | DOPAMINE BLOCKER ; CHEMO INDUCED VOMITING
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| DOMPERIDONE | D2 ANTAG ; CHEMO INDUCED VOMITING
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| DROPERIDOL | ANTI PSYCHOTIC
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| LOXIGLUMIDE | CCK1 ANTAG ; INCREASES GI MOTILITY
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| LOPERAMIDE | CODEINE ANALOGUE ; ANTI DIARRHOEALS
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| LACTULOSE | INCREASE THE OSMOLARITY OF THE LUMINAL CONTENTS THEREBY INCREASING THE STIMULATION OG THE GUT WALLS FOR PERISTALSIS
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| LIQUID PARAFFIN | Luminally active
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| Docusate | DECREASES SURFACE TENSION OF FLUIDSM
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| MAGNESIUM SULFATE | INCREASE OSMOLARITY AND HENCE THE BULK BY DRAWING WATER , PREVENTS CONVULSIONS AND REDUCES BP IN PRE ECCLAMPSIA AND ECCLAMPSIA PATIENTS
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| POLYETHYLENE GLYCOL | HIGHLY OSMOTIC , SO IT RETAINS WATER AND INCREASES THE BULK
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| ALOE | IRRITATE THE WALL AND STIMULATE PERISTALSIS
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| CASTOR OIL | IRRITATE THE WALL ANC STIMULATES PERISTALSIS
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| RACECADOTRIL | ENKEPHALINASE INHIBITOR WHICH INCREASES ENKEPHALINS AND IRRITATES THE WALL AND STIMULATES PERISTALSIS
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| OCTREOTIDE | REDUCES MOTILITY OF GI
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| CHENODEOXYCHOLIC ACID | REDUCES CH , HMGCOA REDUCTASE INHIB , INCREASES LITHOLYTIC
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| URSODIOL | INHIBITS ABSORPTION OF CHOLESTEROL , REDUCES CH , LOWERS SATURATION INDEX OF BILE , SO THAT IT ISN'T LITHOGENIC
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| HALOTHANE | INHALATIONAL ANAESTHETIC
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| PROPOFOL | INTRAVENOUS ANAESTHETIC
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| ETOMIDATE | INTRAVENOUS ANAESTHETIC
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| KETAMINE | DISSOCIATIVE ANAESTHETIC , calmness and psychic indifference without loss of consciousness and analgesia , non competitive blocker of nmda
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| METHOXYFLURANE | INHALATIONAL ANAESTHETIC
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| ISOFLURANE | INTRAVENOUS ANAESTHETIC
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| CHLORDIAZEPOXIDE | BENZODIAZEPINE , ANXIOLYTICS
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| ZOPICLONE | BZ1 RECEPTORS AND HAVE HYPNOTIC
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| ZOLPIDEM | BZ1 RECEPTOR
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| ZALEPLON | BZ1 receptor
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| FLUMAZENIL | BZD ANTAG
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| IPSASPIRONE | 5HT1 agonist
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| GESPIRONE | 5HT1 AGONIST
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| THIOPENTAL | ACTS ON CHANNEL MODULATORY SITE OF GABA , INCREASES DURATION OF CHLORIDE
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| METHOHECITAL | BARB , ultra short acting
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| PHENOBARBITAL | BARB , long acting
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| PENTOBARB | Short acting
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| DESIPRAMINE | BLOCKS EOINEPHRINE
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| NORTRYPTILLINE | CLOCKS EPINEPHRINE
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| PROTRIPTYLINE | BLOCKS EPINEPHRINE
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| SERTRALINE | INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
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| FLUOXETINE | INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
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| CITALOPRAM | INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
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| FLUVOXAMINE | INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
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| PAROXETINE | INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
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| TRAZODONE | INHIBITS UPTAKE OF 5HT
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| MIANSERIN | BLOCKS ALPHA 2
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| MIRTAZAPINE | 5 HT1
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| SELEGILINE | INHIBIT MAO B
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| LITHIUM | INHIBITS IP2 TO IP1 AND IP1 TO IP
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| ETHANOL | CNS DEP , DEC OF MYOCARDIUM , CUTANEOUS VASODILATION , DIURESIS , RESP DEPRESSION , IRRITABILITY
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| MORPHINE | Increases pain threshold , euphoria , anaesthetic , cough suppressant , diarrhoea ,
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| NALOXONE | ANTAG TO MORPHINE
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| PENTAZOCINE | WEAK ANTAG OF MU , AG OF KAPPA A ND WEAK AG OF DELTA
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| BUPRENORPHINE | PARTIAL AG OF MU , ANTAG OF KAPPA ,
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| NALTREXONE | ANTAG OF MORPHEINE
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| CARBAMAZEPINE | BLOCKS Na CHANNELS , TRIGEMINAL ANALGESIA
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| ETHISUXIMIDE | BLOCKS Ca channels
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| VALPROIC ACID | BLOCKS NA , GLUTAMATE , INHIBITS GABA TRANSAMINASE ,
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| Vigabatrin | IRREVERSIBLE INHIBITOR OF GABA TRANSAMINASE
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| TIAGABINE | INHIBIT GABA UPTAKE
🗑
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| TOPIRAMATE | BLOCKS NA CHANNELS , INCREASES GABA , INHIBITS GLUTAMATE
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| LAMOTRIGINE | DIRECTLY BLOCKS Na channel
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| FELBAMATE | BLOCKS NMDA
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| TOLCAPONE | COMT INHIB
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| ENTACAPONE | Comt INHIB
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| AMANTADINE | PREVENTS DOPAMINE UPTAKE AND FACILITATES PRESYNAPTIC RELEASE OF DA , BLOCKS NMDA , ANTI MUSCARINIC
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| SALBUTAMOL | BETA BLOCKER. , TOCOLYTIC
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| TERBUTALINE | BETA BLOCKER , TOCOLYTIC
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| NIFEDIPINE | PERIPHERAL VASODILATOR , TOCOLYTIC
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| METYRAPONE | 11 BETA HYDROXYLASE ENZYME INHIBITOR
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| AMINOGLUTETHAMIDE | BLOCKS CONVERSION OF CHOLESTEROL TO PREGNENOLONE
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| MITOTANE |
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| CLOMIPHENE | SSRM , INCREASES FSH AND LH
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| TAMOXIFEN | ANTAG OF ESTROGEN IN BREAST AND AG OF ESTROGEN IN UTERUS , BONE , PITUITARY , LIVER
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| DOLOXIFEN | ANTAG OF ESTROGEN IN BREAST , AG IN BONE , LIVER , PITUITARY
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| TOREMIFEN | ANTAG IN BREAST , AG IN BONE M LIVER , PITUITARY , UTERUS
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| FULVESTRANT | ANTAG IN BREAST , AG IN BONE , LIVER , PITUITARY AND UTERUS
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| RALOXIFENE | ANTIESTROGEN IN BREAST , ENDOMETRIUM , ESTROGEN IN BONE , COAGULATION OF BLOOD , LIPID META
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| CENTCHROMAN | SERM
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| MIFEPRISTONE | BLOCKS PROGESTERONE
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| GOSSYPOL | REDUCES SPERM COUNT AND MOTILITY
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| ANASTROZOLE | INHIBIT AROMATASE AND SO ESTROGEN
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| LETROZOLE | INHIBIT AROMATASE AND SO ESTROGEN
🗑
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| FADROZOLE | INHIBIT AROMATASE AND SO ESTROGEN
🗑
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| VOROZOLE | INHIBIT AROMATASE AND SO ESTROGEN
🗑
|
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| LEVOTHYROXINE | T4
🗑
|
||||
| CARBIMAZOLE | INHIBITS THYROID PEROXIDASE , INCORPORATION OF IODINE INTO THE TYROSINE , AND INHIB OF COUPLING OF IODITYROSYL RESIDUES
🗑
|
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| METHIMAZOLE | INHIBITS THYROID PEROXIDASE , INCORPORATION OF IODINE INTO THE TYROSINE , AND INHIB OF COUPLING OF IODITYROSYL RESIDUES
🗑
|
||||
| LUGOLS IODINE | INCREASEDIODINE INHIBITS ITS OWN TRANSPORT AS WELL AS THE RELEASE OF THE HORMONE
🗑
|
||||
| PERCHLORATE | COMPETITIVE INHIBITOR OF THYROIDAL IODINE TRANSPORT VIA THE Na/I TRANSPORTER
🗑
|
||||
| THIOCYANATE | COMPETITIVE INHIBITOR OF THYROIDAL IODINE TRANSPORT VIA THE Na/I TRANSPORTER
🗑
|
||||
| INSULIN LISPRO | ULTRA SHORT ACTING
🗑
|
||||
| INSULIN ASPARTAME | ULTRA SHORT ACTING
🗑
|
||||
| INSULIN ZINC SUSPENSION /SEMILENTE | SHORT ACTING
🗑
|
||||
| ISOPHANE INSULIN /LENTE | INTERMEDIATE ACTING
🗑
|
||||
| INSULIN GLARGINE | LONG ACTING
🗑
|
||||
| UKTRALENTE | LONG ACTING
🗑
|
||||
| TOLBUTAMIDE | BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN ulfonylurea
🗑
|
||||
| CHLORPROPAMIDE | BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN sulfonylurea
🗑
|
||||
| REPAGLINIDE | BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN meglitinide analogues
🗑
|
||||
| NATEGLINIDE | BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN meglitinide
🗑
|
||||
| METFORMIN | iNCREASES UPTAKE AND UTIKISATION OF GLUCOSE AND PREVENTS GLUCONEOGENESIS AND GLYCIGEN AND INCREASES BINDUNG OF INSUKIN TO ITS RECEPTOR , SLOWS GLUCOSE ABSORPTION FROM THE STOMACH, biguanids
🗑
|
||||
| PHENFORMIN | iNCREASES UPTAKE AND UTIKISATION OF GLUCOSE AND PREVENTS GLUCONEOGENESIS AND GLYCIGEN AND INCREASES BINDUNG OF INSUKIN TO ITS RECEPTOR , SLOWS GLUCOSE ABSORPTION FROM THE STOMACH , biguanides
🗑
|
||||
| ACARBOSE | Inhibits alpha gkycosidase and thus absorption of glucose
🗑
|
||||
| MIGLITO | Inhibits alpha gkycosidase and thus absorption of glucose
🗑
|
||||
| ROSIGLITAZONE | AGONIST TO PPAR GAMMA WHICH BINDS WITH RETINOID X RECEPTOR WHICH INCREASES LIPOGENESIS AND PROMOTES UPTAKE OF FATTY ACIDSAND GLUCOSE
🗑
|
||||
| PIOGLITAZONE | AGONIST TO PPAR GAMMA WHICH BINDS WITH RETINOID X RECEPTOR WHICH INCREASES LIPOGENESIS AND PROMOTES UPTAKE OF FATTY ACIDSAND GLUCOSE
🗑
|
||||
| CODEINE | CENTRALLY ACTING ANTITUSSIVE
🗑
|
||||
| DEXTROMETHORPHAN | CENTRALLY ACTING ANTITUSSIVE
🗑
|
||||
| BENZONATATE | INHIBITS PERIPHERAL RECEPTORS AND CENTRAL COUGH CENTRE AFFERENTS
🗑
|
||||
| PRENOXDIAZINE | SUPRESSES PERIPHERAL RECEPTORS
🗑
|
||||
| AMMONIUM CHLORIDE | STIMULATES BRONCHIAL CELLZ TI SECRETE MUCUS AND CIKIA TO CLEAR IT mucokinetic
🗑
|
||||
| SODIUM CITRATE | STIMULATES BRONCHIAL CELLZ TI SECRETE MUCUS AND CIKIA TO CLEAR IT mucokinetic
🗑
|
||||
| ACETYL CYSTEINE | MUCOLYTIC DECREASES VISCOSITY OF MUCUS BY SPLITTING DISULFIDE BONDS OF MUCOPROTEIN
🗑
|
||||
| BROMHEXINE | DEPOLYMERISES MUCOPOLYSACCHARIDES OF MUCUS
🗑
|
||||
| DORNASE ALFA | DNAase SPLITS DNA
🗑
|
||||
| SULFACYTINE | ORAL , SHORT ACTING SULFONAMIDE
🗑
|
||||
| SULFADIAZINE | ORAL , SHORT ACTING
🗑
|
||||
| SULFISOXOZOLE | ORAL , SHORT ACTING
🗑
|
||||
| SULFAMETHAZOLE | ORAL SHORT ACTING SULFONAMIDE
🗑
|
||||
| SULFAMETHAXOZOLE | ORAL INTERMEDIATE ACTING SULFONAMIDE
🗑
|
||||
| SULFADOXINE | ORAL LONG ACTING SULFONAMIDE
🗑
|
||||
| OLSALAZINE | ORAL NON ABSORBABLE SULFONAMIDE
🗑
|
||||
| SILVER SULFADIAZINE | TOPICAL SULFONAMIDE
🗑
|
||||
| SULFACETAMIDE | TOPICAL SULFONAMIDE
🗑
|
||||
| NORFLOXACIN | FIRST GENERATION FLUOROQUINOLONES
🗑
|
||||
| CIPROFLOXACIN | FIRST GENERATION FLUOROQUINOLONES
🗑
|
||||
| OFLOXACILIN | FIRST GENERATION FLUOROQUINOLONES
🗑
|
||||
| PEFLOXACIN | FIRST GENERATION FLUOROQUINOLONES
🗑
|
||||
| LOMEFLOXACIN | FIRST GENERATION FLUOROQUINOLONES
🗑
|
||||
| LEVOFLOXACIN | SECOND GENERATION FLUOROQUINOLONES
🗑
|
||||
| GATIFLOXACIN | THIRD GENERATION FLUOROQUINOLONES
🗑
|
||||
| SPARFLOXACIN | THIRD GENERATION FLUOROQUINOLONES
🗑
|
||||
| MOXIFLOXACIN | FOURTH GENERATION FLUOROQUINOLONES
🗑
|
||||
| ALATROFLOXACIN | FOURTH GENERATION FLUOROQUINOLONES
🗑
|
||||
| TROVAFLOXACIN | FOURTH GENERATION FLUOROQUINOLONES
🗑
|
||||
| PHENAZOPYRIDINE | URINARY ANALGESIC ;
🗑
|
||||
| NITROFURANTOIN | INHIBITS ACETYL COA WHICH BLOCKS CARB META AND SO THE BACTERIA ; URINARY ANTISEPTIC
🗑
|
||||
| NALIDIXIC ACID | NON FLUORINATED QUINOLONES ; URINARY ANTISEPTICS
🗑
|
||||
| PENICILLIN V | ORAL NATURAL PENICILLIN
🗑
|
||||
| PENICILLIN G | IM OR IV NATURAL PENICILLIN
🗑
|
||||
| PROCAINE PENICILLIN | IM DEPOT ; BETA LACTAMASE SENSITIVE
🗑
|
||||
| BENZATHINE PENCILLIN | IM DEPOT ; BETA LACTAMASE PENICILLIN
🗑
|
||||
| CLOXACILLIN | ORAL LACTAMASE RESISTANT PENICILLIN
🗑
|
||||
| DICLOXACILLLIN | ORAL LACTAMASE RESISTANT PENICILLIN
🗑
|
||||
| METHICILLIN | IM OR IV LACTAMASE RESISTANT PENICILLIN
🗑
|
||||
| CLAVULANIC ACID | BETA LACTAMASE INHIBITOR ; BIND IRREVERSIBLY TO THE CATALYTIC SITE OF LACTAMASE
🗑
|
||||
| SULBACTAM | BETA LACTAMASE INHIBITOR
🗑
|
||||
| TAZOBACTAM | BETA LACTAMASE INHIBITOR
🗑
|
||||
| CEFAZOLIN | FIRST GENERATION CEPALOSPORIN
🗑
|
||||
| CEFALOTHIN | FIRST GENERATION CEPHALOSPORIN
🗑
|
||||
| CEFADROXIL | FIRST GENERATION CEPHALOSPORIN
🗑
|
||||
| CEFARADINE | FIRST GENERATION CEPHALOSPORIN
🗑
|
||||
| CEFUROXIME | SECOND GENERATION CEPHALOSPORIN ORAL
🗑
|
||||
| CEFOXITIN | SECOND GENERATION CEPHALOSPORIN PARENTERAL
🗑
|
||||
| CEFACLOR | SECOND GENERATION CEPHALOSPORIN ORAL
🗑
|
||||
| CEFOTETAN | SECOND GENERATION CEPHALOSPORIN PARENTERAL
🗑
|
||||
| CEFIXIME | THIRD GENERATION CEPHALOSPORIN ORAL
🗑
|
||||
| CEFTIZOXIME | THIRD GENERATION CEPHALOSPORIN PARENTERAL
🗑
|
||||
| CEFTRIAXONE | THIRD GENERATION CEPHALOSPORIN PARENTERAL
🗑
|
||||
| CEFDINIR | THIRD GENERATION CEPHALOSPORIN ORAL
🗑
|
||||
| CEFPODOXIME | THIRD GENERATION CEPHALOSPORIN ORAL
🗑
|
||||
| CEFPEROME | FOURTH GENERATION CEPHALOSPORIN PARENTERAL
🗑
|
||||
| CEFIPIME | FOURTH GENERATION CEPHALOSPORIN PARENTERAL
🗑
|
||||
| AZTREONAM | NEWER BETA LACTAM ANTIBIOTICS
🗑
|
||||
| CARBAPENEM | NEWER BETA LACTAM
🗑
|
||||
| VANCOMYCIN | INHIBITS GRAM POSITIVE CELL WALL SYNTHESIS BY COMPLEXING D ALANYL D ALANINE PORTION OF TERMINAL END OF PEPTIDOGLYCAN
🗑
|
||||
| TEICOPLANIN | INHIBITS GRAM POSITIVE CELL WALL SYNTHESIS BY COMPLEXING WITH D ALANYL D ALANINE PORTION OF THE TERMINAL END OF THE PEPTIDOGLYCAN
🗑
|
||||
| BACITRACIN | BLOCKS THE FUNCTION OF LIPID CARRIER MOLECULES WHICH TRANSFERS CELL WALL SUBUNITS ACROSS CELL MEMBRANE
🗑
|
||||
| FOSFOMYCIN | INHIBITS BACTERIAL CELL WALL SYNTHESIS BY INACTIVATING PYRUVYL TRANSFERASE WHICH IS CRUCIAL FOR THE FORMATION OF UDP N ACETYL MURAMIC ACID WHICH IS FOUND IN THE CELL WALL
🗑
|
||||
| STREPTOMYCIN | AMINOGLYCOSIDE
🗑
|
||||
| GENTAMYCIN | AMINOGLYCOSIDE
🗑
|
||||
| KANAMYCIN | AMINOGLYCOSIDE
🗑
|
||||
| AMIKACIN | AMINOGLYCOSIDE
🗑
|
||||
| NEOMYCIN | AMINOGLYCOSIDE , TOPICAL
🗑
|
||||
| SOFRAMYCIN | AMINOGLYCOSIDE TOPICAL
🗑
|
||||
| PAROMOMYCIN | AMINOGLYCOSIDE , TOPICAL
🗑
|
||||
| ERYTHROMYCIN | MACROLIDE
🗑
|
||||
| ROXITHROMYCIN | MACROLIDE
🗑
|
||||
| CLARITHROMYCIN | MACROLIDE
🗑
|
||||
| AZITHROMYCIN | MACROLIDE
🗑
|
||||
| SPIRAMYCIN | MACROLIDE
🗑
|
||||
| CLINDAMYCIN | LINCOSAMIDE
🗑
|
||||
| TELITHROMYCIN | KETOLIDE
🗑
|
||||
| LINEZOLID | OXAZOLIDINONE
🗑
|
||||
| PRISTINNAMYCIN | COMBI OF STREPTOGRAMIN B AND STREPTOGRAMIN A IN A 30 : 70 RATIO ; BINDS TO 50S ( STREPTOGRAMINS)
🗑
|
||||
| POLYMYXIN B | DISRUPTS THE BACTERIAL CELL MEMBRANE OSMOTIC INTEGRITY BY DISPLACING CALCIUM AND MAGNESIUM FROM MEMBRANE LIPID PHOSPHATES
🗑
|
||||
| MUPIROCIN | INHIBITS BACTERIAL RNA AND PROTEIN SYNTHESIS BY BINDING TO ISOLEUCYL T RNA SYNTHETASE
🗑
|
||||
| FUSIDIC ACID | INHIBITS PROTEIN ELONGATION
🗑
|
||||
| TETRACYCLINE |
🗑
|
||||
| CHLORAMPHENICOL |
🗑
|
||||
| DOXYCYCLINE | TETRACYCLINE
🗑
|
||||
| DEMECLOCYCLINE | TETRACYCLINE
🗑
|
||||
| MINOCYCLINE | TETRACYCLINE
🗑
|
||||
| ISONIAZID | INHIBITS SYNTHESIS OF MYCOLIC ACID WHICH IS AN ESSENTIAL COMPONENT OF MYCOBACTERIAL CELL WALL
🗑
|
||||
| RIFAMPICIN | BINDS STRONGLY TO THE BETA SUBUNIT OF BACTERIAL DNA DEPENDENT RNA POLYMERASE , SO INHIBITS RNA SYNTHESIS
🗑
|
||||
| ETHAMBUTOL | INHIBITS ARABINOSYL TRANSFERASE ENZYME TO PREVENT POLYMERISATION OF ARABINOGLYCANS IN MYCOBACTERIAL CELL WALL
🗑
|
||||
| PYRAZINAMIDE | IT ENTERS THE MYCOBACTERIUM AND GETS CONVERTED TO PYRAZINOIC ACID BY BACTERIAL PYRAZINAMIDASE WHICH INHIBITS MYCOBACTERIAL FATTY ACID SYNTHASE I AND DISRUPTS MYCOLIC ACID FORMATION
🗑
|
||||
| DAPSONE | INHIBITION OF BACTERIAL FOLIC ACID SYNTHESIS
🗑
|
||||
| CLOFAZIMINE | BINDS TO THE MYCOBACTERIAL DNA , INTERFERES WITH ITS TEMPLATE FUNCTION AND INHIBITS MYCOBACTERIAL GROWTH
🗑
|
||||
| ACLOMETASONE | TOPICAL GLUCOCORTICOID
🗑
|
||||
| AMCINONIDE | TOPICAL GLUCOCORTICOID
🗑
|
||||
| BELCOMETHASONE | TOPICAL/INHALATIONAL GLUCOCORTICOID
🗑
|
||||
| BUDESOINDE | INHALATIONAL GLUCOCORTICOID
🗑
|
||||
| FLUCINOLONE | TOPICAL GLUCOCORTICOID
🗑
|
||||
| FLUTICASONE | TOPICAL GLUCOCORTICOID
🗑
|
||||
| MEDRYSONE | OPTHALMIC GLUCOCORTICOID
🗑
|
||||
| LEVOTHYROXINE SODIUM | INCREASES T4 TO T3 AND REDUCES TSH STIMULATION BY NEGATIVE FEEDBACK AND THUS CAN BE USED IN NON ENDEMIC GOITRE ; ALSO USED IN REFRACTORY ANAEMIAS , NON HEALING WOUNDS , CHRONIC CONSTIPATION , MENSTRUAL DISORDERS AND INFERTILITY
🗑
|
||||
| LIOTHYRONINE | NOT USED AS MUCH ; MYXOEDEMA COMA , SHORT TERM SUPRESSION OF TSH IN THYROIDECTOMY ,
🗑
|
||||
| PROPYLTHIOURACIL | INHIBIT PEROXIDASE , COUPLING , INCORPORATION OF IODINE INTO TYROSYL RESIDUES , AND PERIPHEARL CONVERSION OG T4 TO T3
🗑
|
||||
| CARNBIMAZOLE | INHIBIT PEROXIDASE , COUPLING , INCORPORATION OF IODINE INTO TYROSYL RESIDUES , AND PERIPHEARL CONVERSION OG T4 TO T3
🗑
|
||||
| METHCARBIMAZOLE | INHIBIT PEROXIDASE , COUPLING , INCORPORATION OF IODINE INTO TYROSYL RESIDUES , AND PERIPHEARL CONVERSION OG T4 TO T3
🗑
|
||||
| RADIOACTIVE IODINE | EVALUATING THYROID FUNCTIONS , NON SURGICAL THYROID ABLATION , BETA PARTICLES DESTROY PARENCHYMA
🗑
|
||||
| LUOGOLS IODINE | LIMITS ITS OWN TRANSPORT , THYROID HORMONE RELEASE , ; PREPARE PATIENT FOR THYROIDECTOMY , BY MAKING IT LESS VASCULAR AND MORE COMPACT ; TREAT SEVERE THYROTOXICOSIS
🗑
|
||||
| PERCHLORATE ION | COMPETITIVE INHIBITOR OF THYROIDAL IODIDE TRANSPORT VIA NA , I TRANSPORTER . RARELY USED CUZ IT CAUSES FATAL APLASTIC ANAEMIA AND GASTRIC ULCERS
🗑
|
||||
| THIOCYANATE | COMPETITIVE WITH THE IODIDE TRANSPORTER
🗑
|
||||
| ORAL IPODATE | HYPERTHYROID , INHIBIT 5 DEIODINASE AND PREVENT CONVERSION OF T4 TO T3
🗑
|
||||
| CASPOFUNGIN | INHIBITS CELL WALL SYNTHESIS
🗑
|
||||
| AMPHOTERICIN B | MACROLIDE , BINDS TO ERGOSTEROL , HENCE FORMING PORES CAUSE LEAKING OF IONS AND FURTHER LYSIS
🗑
|
||||
| NYSTATIN | BINDS TO ERGOSTEROL AND HENCE FORMS PORES CAUSING LEAKING OF IONS AND FURTHER LYSIS
🗑
|
||||
| TERBINAFINE | INHIBITS LANOSTEROL TO ERGOSTEROL BY SQUALENE EPOXIDASE , RESULTING IN ACC OF SQUALENE CAUSING LYSIS
🗑
|
||||
| NAFTIFINE | INHIBITS LANOSTEROL TO ERGOSTEROL CAUSING LYSIS
🗑
|
||||
| BUTENAFINE | INHIBITS LANOSTEROL TO ERGOSTEROL CAUSING LYSIS
🗑
|
||||
| MICONAZOLE | BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
🗑
|
||||
| KETOCONAZOLE | BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
🗑
|
||||
| FLUCONAZOLE | BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
🗑
|
||||
| ITRACONAZOLE | BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
🗑
|
||||
| VORICONAZOLE | BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
🗑
|
||||
| GRISEOFULVIN | INTERACTS WITH POLYMERISED MICROTUBULES CAUSING DISRUPTION
🗑
|
||||
| TERBINAFINE |
🗑
|
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Popular Pharmacology sets