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Mechanism of action

MOA of drugs

DRUGMOA
Competitive blockers (SM Relaxants) Prevent ACh from binding to the NMJ and prevent depolarisation
Persistent depolarisers (SM Relaxants) ACh analogues binding to NMJ and depolarise for a longer time
DIRECTLY ACTING MUSCLE RELAXANTS PREVENT CALCIUM ION CHANNEL
MEPHENESIN INHIBIT POLYSYNAPTIC REFLEXES
BENZODIAZEPINE INCREASE GABA CHANNELS
GABA DERIVATIVE INCREASES GABA ACTION
CENTRAL ALPHA-2 AGONIST PRESYNAPTIC INHIBITION WHICH INHIBITS RELEASE OF EXCITATORY AMINO ACIDS
QUININE DECREASES THE EXCITABILITY OF THE NMJ
BOTULINUM PREVENTS CALCIUM DEPENDENT ACh RELEASE
LOCAL ANAESTHETICS BLOCK Na CHANNELS
THIAZIDE DIURETICS REDUCE REABSORPTION OF Na AND WATER IN THE PROXIMAL PART OF DISTAL TUBULE
LOOP DIURETICS REDUCE REABSORPTION IN LIMB OF LOOP OF HENLE
POTASSIUM SPARING DIURETICS REDUCE REABSORPTION OF Na AT THE DISTAL PART OF THE DISTAL TUBULE AND ALSO REDUCE K EXCRETION
ALDOSTERONE RECEPTOR ANTAG REDUCE ALDOSTERONE IN ORDER TO PREVENT Na AND WATER REABSORPTION IN DT AND CT
OSMOTIC DIURETICS INCREASE THE OSMOLARITY OF THE FILTRATE AND INCREASES THE FILTRATION LOAD AND REDUCES REABSORPTION . DUE TO HIGH OSMOTIC PRESSURE ADH IS ALSO INEFFECTIVE
CA INHIBITORS PREVENT THE ENZYME FEOM ACTING AND HENCE PREVENT Na AND WATER REABSORPTION
XANTHINES DILATES AFFERENT ARTERIOLES and prevents reabsorption of water and Na
VASOPRESSIN INCREASES REABSORPTION OF Na AND WATER
HYDRALAZINE INCREASES NITRIC OXIDE AND K CHANNELS TO CAUSE VASODILATION
MINOXIDIL K CHANNEL OPENER
BUMETANIDE BLOCKS REABSORPTION OF SODIUM AND WATER IN THE ASCENDING LIMB OF LOOP OF HENLE
CARVEDILOL ALPHA 1 AND BETA 1 , 2 BLOCKER ; VENTRICULAR FAILURE
PRAVASTATIN HMG CoA REDUCTASE INHIBITOR
CHOLESTYRAMINE BILE ACID BINDING RESINS; USED IN HYPERCHOLESTEROLEMIA
COLESTIPOL BILE ACID BINDING RESINS; USED IN HYPERCHOLESTEROLEMIA
COLESELVAM BILE ACID BINDING RESINS; USED IN HYPERCHOLESTEROLEMIA
EZETIMIBE INHIBITS INTESTINAL ABSORPTION OF CHOLESTEROL
GEMFIBROZIL LpL ACTIVATORS
FENOFIBRATE LpL ACTIVATORS
BEZAFIBRATE LpL ACTIVATORS
NIACIN / NICOTINIC ACID INHIBITS APO B CONTAINING LIPOPROTEINS
DIMENHYDRINATE ANTI HISTAMINIC (I) ; ANTI MOTION
DIPHENHYDRAMINE ANTI HISTAMINIC (I) ; ANTI MOTION SICKNESS , ANTI PARKINSONS , LOCAL ANAESTHETIC
DOXYLAMINE ANTI HISTAMINIC (I) ; SLEEP AID
HYDROXYZINE ANTI HISTAMINIC (I) ; ANTI EMETIC
PROMETHAZINE ANTI HISTAMINIC (I); ANTI EMETIC , ANTI PARKINSON , LA
CYCLIZINE ANTI HISTAMINIC (I); ANTI MOTION
MECLIZINE ANTI HISTAMINIC (I) ; anti motion
FEXOFENADINE ANTI HISTAMINIC (II) ; ANTI INFLAMMATORY
CETIRIZINE ANTI HISTAMINIC (II) ;
LEVOCETIRIZINE ANTI HISTAMINIC (II) ;
DESLORATIDINE ANTI HISTAMINIC (II) ; ANTI INFLAMMATORY
LORATADINE ANTI HISTAMINIC (II) ;
CIMETIDINE ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
RANITIDINE ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
FAMOTIDINE ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
NIZATIDINE ANTI H2 ; BLOCK SECRETION OF GASTRIC ACID
CROMOLYN SODIUM HISTAMINE RELEASE INHIBITORS ; ASTHMA , RHINITIS
NEDOCROMOLYN SODIUM HISTAMINE RELEASE INHIBITORS ; ASTHMA , RHINITIS
KETOTIFEN ANTI H1 WITH MAST CELL STABILISING ACTION
BUSPIRONE 5 HT AGONISTS ; ANTI ANXIETY
SUMATRIPTAN 5HT1B , 5HT1C AGONIST , ANTI MIGRAINE
CISAPRIDE 5HT4 AGONISTS , GASTROESOPHAGEAL REFLUX
RENZAPRIDE 5HT4 AGONISTS , GASTROESOPHAGEAL REFLUX
TEGASEROD 5HT4 PARTIAL AGONIST , IRRITABLE BOWEL SYNDROME
DEXFENFLURAMINE NON SELECTIVE 5HT RECEPTOR AGONIST , SPPETITE SUPRESSANT
LSD NON SELECTIVE 5HT AGONIST ; HALLUCINOGEN
KETANSERIN 5HT2A ANTAG , ANTI HYPERTENSIVE , RAYNAUDS DISEASE
RITANSERIN 5HT2A ANTAG
ONDANSETRON 5HT3 ANTAG , POST OP ANTIEMETIC , CHEMOTHERAPY INDUCED ALSO
DOLASETRON 5HT3 ANTAG , POST OP ANTIEMETIC
GRANISETRON 5HT3 ANTAG , POST OP ANTIEMETIC
CLOZAPINE 5HT AND DOPAMINE ANTAG , ANTIPSYCHOTIC
OLANZAPINE 5HT AND DOPAMINE ANTAG , ANTIPSYCHOTIC
RISPERIDONE 5HT AND DOPAMINE ANTAG , ANTIPSYCHOTIC
METHYLSERGIDE 5HT 2A ANTAG ; USED IN MIGRAINE PROPHYLAXIS
CYPROHEPTADINE 5HT 2A ANTAG , POSTGASTRECTOMY AND CARCINOID
ERGOTAMINE PARTIAL AGONIST 5HT ,
BROMOCRIPTINE PARTIAL AGONIST 5HT , PARKINSON
ERGOMETRINE PARTIAL AGONIST 5HT , PREVENT POST PARTUM HAEMORRHAGE
DINOPROSTONE PGE2 ; INDUCING ABORTION , LABOUR AND POST PARTUM HAEMORRHAGE PREVENTION
MISOPROSTOL PGE2 ; ABORTIFACIENT , PEPTIC ULCER
CARBOPROST PGF2ALPHA , ABORTIFACIENT , LABOUR AND POST PARTUM HAEMORRHAGE PREVENTION
ENPROSTIL PGE2 , PEPTIC ULCER
EPOPROSTENOL PGI2 , PREVENT PLATELET AGGREG , DUCTUS ARTERIOSUS , PULMONARY HYPERTENSION
LATANOPROST PGF2 ALPHA , USED IN GLAUCOMA
ALPROSTADIL PGE1 , NALE IMPOTENCE
ZAFIRLUKAST cys LT RECEPTOR ANTAG
MONTELEUKAST cys LT RECEPTOR ANTAG
IRALUKAST cys LT RECEPTOR ANTAG
ZILEUTON LIPOOXYGENASE INHIBITOR ; ANTI ASTHMA AND ANTIINFLAMMATORY
SULFASALAZINE NONSELECTIVE IRREVERSIBLE OF COX , ULCERATIVE COLITIS , ARTHRITIS
SODIUM SALICYLATE NONSELECTIVE IRREVERSIBLE OF COX
METHYL SALICYLATE NONSELECTIVE IRREVERSIBLE OF COX
PHENYLBUTAZONE NON SELECTIVE REVERSIBLE COX
OXYPHENBUTAZONE NON SELECTIVE REVERSIBLE COX
IBUPROFEN NON SELECTIVE REVERSIBLE COX
KETOPROFEN NON SELECTIVE REVERSIBLE COX
MEFENAMIC ACID NON SELECTIVE REVERSIBLE COX , DYEMENNORHOEA , OSTEOARTHRITIS
FLUFENAMIC ACID NON SELECTIVE REVERSIBLE COX
PIROXICAM NON SELECTIVE REVERSIBLE COX , ACUTE GOUT
KETOROLAC NON SELECTIVE REVERSIBLE COX , CONJUNCTIVITIS
DICLOFENAC NON SELECTIVE REVERSIBLE COX
NIMESULIDE WEAK INHIB OF COX1 AND COX2
ETODOLAC PREFERENTIAL COX2
ROFECOXIB SELECTIVE COX2
VAKDECOXIB SELECTIVE COX2
PARACETAMOL COX3 OR REVERSIBLE OF COX1
NEFOPAM NO INHIBITION OF PGs
ASPIRIN NON SLEECTIVE IRREVERSIBLE OF COX , DUCTUS ARTERIOSUS CLOSURE , PRE ECCLAMPSIA , COLON AND RECTAL CANCER , ALZHEIMERS , FAMILIAL COLONIC POLYPOSIS , SLOWDOWN CATARACT
SALICYLIC ACID NON SELECTIVE IRREVERSIBLE COX INHIB , KERATOLYTIC
INDOMETHACIN NON SELECTIVE REVERSIBLE COX INHIB
COLCHICINE INHIBITS NEUTROPHIL MIGRATION INTO THE JOINTS ; ACUTE GOUT
PREDNISOLONE SUPRESSES INFLAMMATION ; ACUTE GOUT
ALLOPURINOL INHIBITS XANTHINE OXIDASE , SO URIC ACID ; CHRONIC GOUT
PROBENECID PROMOTES EXCRETION OF URIC ACID ; CHRONIC GOUT
SULFINPYRAZONE PREVENTS REABSORPTION OF URIC ACID
INFLIXIMAB INHIBITS T CELL AND MACROPHAGE
LEFLUNOMIDE INHIBITS T CELL AND ANTIBODY PRODUCTION ; IMMUNOMODULATOR
METHOTREXATE FOLIC ACID ANTAG ; IMMUNOMODULATOR
CYCLOSPORINE INHIBITS IL1 AND IL2 RECEPTORS ; INHIBITS T CELL INTERACTION AND RESPONSIVENESS
AZATHIOPRINE PRO DRUG OF 6 MERCAPTOPURINE MAKES A NON FUNCTIONAL NA WHICH IS INCORPORATED INTO DNA AND IS NON FUNCTIONAL ; INHIBITS T CELLS ; USED IN GRAFT TRANSPLANT
AURANOFIN ALTERS MORPHOLOGY OF MACROPHAES AND PREVENTS JOINT DESTRUCTION
HYDROXYCHLOROQUINE SUPRESS T CELL FUNCTION ; RA
SULFASALAZINE ORAL , NON ABSORBABLE .IT IS METABOLISED TO SULFAPYRIDINE AND 5 ASA ; SULFAPYRIDINE MIGRATES TO JOINTS AND USED , WHILE 5 ASA IS USED IN RA
CYCLOPHOSPHAMIDE CROSS LINKS DNA TO PREVENT CELL REPLICATION ; CANCER AND RA AS IMMUNOSUPRESSANT
SUCRALFATE POLYMERISES BY CROSS LINKING OF MOLECULES TO FORM A GEL OVER THE ULCER
COLLOIDAL BISMUTH SUBCITRATE IT CONVERTS INTO BISMUTH OXYCHLORIDE AND THEN CHELATES WITH GLYCOPROTEINS TO FORM A GEL OVER THE ULCER
PANTOPRAZOLE BLOCKS H+/K+/ATPase AND PREVENTS FORMATION OF ACID
OMEPRAZOLE BLOCKS H+/K+/ATPase AND PREVENTS FORMATION OF ACID
ESOMEPRAZOLE BLOCKS H+/K+/ATPase AND PREVENTS FORMATION OF ACID
SODIUM ALGINATE FORMS A GEL WITH THE ACID
SODIUM BICARBONATE SYSTEMIC ANTACID , barb poisoning
ALUMINIUM HYDROXIDE NON SYSTEMIC BUFFER ANTACID
MAGNESIUM TRISILICATE NON SYSTEMIC BUFFER ANTACID
CALCIUM CARBONATE NON SYSTEMIC NON BUFFER ANTACID
MAGNESIUM HYDROXIDE NON SYSTEMIC NON BUFFER ANTACID
CARBENOXOLONE SODIUM INCREASES PRODUCTION OF MUCUS
CLARITHROMYCIN BLOCKS 50S RIBOSOMES ; ANTI HELICOBACTER
AMOXICILLIN PENICILLIN GRP ; ANTI HELICOBACTER
METRONIDAZOLE ANAEROBIC ; ANTI HELICOBACTER
CINNARIZINE ANTI HISTAMINIC , CALCIUM BLOCKER ; MOTION SICKNESS
PROCHLORPERAZINE 5HT3 ANTAG AND D2 BLOCKING ANTAGS ; CHEMO INDUCED VOMITING
METOCLOPRAMIDE DOPAMINE BLOCKER ; CHEMO INDUCED VOMITING
DOMPERIDONE D2 ANTAG ; CHEMO INDUCED VOMITING
DROPERIDOL ANTI PSYCHOTIC
LOXIGLUMIDE CCK1 ANTAG ; INCREASES GI MOTILITY
LOPERAMIDE CODEINE ANALOGUE ; ANTI DIARRHOEALS
LACTULOSE INCREASE THE OSMOLARITY OF THE LUMINAL CONTENTS THEREBY INCREASING THE STIMULATION OG THE GUT WALLS FOR PERISTALSIS
LIQUID PARAFFIN Luminally active
Docusate DECREASES SURFACE TENSION OF FLUIDSM
MAGNESIUM SULFATE INCREASE OSMOLARITY AND HENCE THE BULK BY DRAWING WATER , PREVENTS CONVULSIONS AND REDUCES BP IN PRE ECCLAMPSIA AND ECCLAMPSIA PATIENTS
POLYETHYLENE GLYCOL HIGHLY OSMOTIC , SO IT RETAINS WATER AND INCREASES THE BULK
ALOE IRRITATE THE WALL AND STIMULATE PERISTALSIS
CASTOR OIL IRRITATE THE WALL ANC STIMULATES PERISTALSIS
RACECADOTRIL ENKEPHALINASE INHIBITOR WHICH INCREASES ENKEPHALINS AND IRRITATES THE WALL AND STIMULATES PERISTALSIS
OCTREOTIDE REDUCES MOTILITY OF GI
CHENODEOXYCHOLIC ACID REDUCES CH , HMGCOA REDUCTASE INHIB , INCREASES LITHOLYTIC
URSODIOL INHIBITS ABSORPTION OF CHOLESTEROL , REDUCES CH , LOWERS SATURATION INDEX OF BILE , SO THAT IT ISN'T LITHOGENIC
HALOTHANE INHALATIONAL ANAESTHETIC
PROPOFOL INTRAVENOUS ANAESTHETIC
ETOMIDATE INTRAVENOUS ANAESTHETIC
KETAMINE DISSOCIATIVE ANAESTHETIC , calmness and psychic indifference without loss of consciousness and analgesia , non competitive blocker of nmda
METHOXYFLURANE INHALATIONAL ANAESTHETIC
ISOFLURANE INTRAVENOUS ANAESTHETIC
CHLORDIAZEPOXIDE BENZODIAZEPINE , ANXIOLYTICS
ZOPICLONE BZ1 RECEPTORS AND HAVE HYPNOTIC
ZOLPIDEM BZ1 RECEPTOR
ZALEPLON BZ1 receptor
FLUMAZENIL BZD ANTAG
IPSASPIRONE 5HT1 agonist
GESPIRONE 5HT1 AGONIST
THIOPENTAL ACTS ON CHANNEL MODULATORY SITE OF GABA , INCREASES DURATION OF CHLORIDE
METHOHECITAL BARB , ultra short acting
PHENOBARBITAL BARB , long acting
PENTOBARB Short acting
DESIPRAMINE BLOCKS EOINEPHRINE
NORTRYPTILLINE CLOCKS EPINEPHRINE
PROTRIPTYLINE BLOCKS EPINEPHRINE
SERTRALINE INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
FLUOXETINE INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
CITALOPRAM INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
FLUVOXAMINE INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
PAROXETINE INCREASE SEROTONIN IN SYNAPTIC CLEFT BY PREVENTING NEURONAL UPTAKE
TRAZODONE INHIBITS UPTAKE OF 5HT
MIANSERIN BLOCKS ALPHA 2
MIRTAZAPINE 5 HT1
SELEGILINE INHIBIT MAO B
LITHIUM INHIBITS IP2 TO IP1 AND IP1 TO IP
ETHANOL CNS DEP , DEC OF MYOCARDIUM , CUTANEOUS VASODILATION , DIURESIS , RESP DEPRESSION , IRRITABILITY
MORPHINE Increases pain threshold , euphoria , anaesthetic , cough suppressant , diarrhoea ,
NALOXONE ANTAG TO MORPHINE
PENTAZOCINE WEAK ANTAG OF MU , AG OF KAPPA A ND WEAK AG OF DELTA
BUPRENORPHINE PARTIAL AG OF MU , ANTAG OF KAPPA ,
NALTREXONE ANTAG OF MORPHEINE
CARBAMAZEPINE BLOCKS Na CHANNELS , TRIGEMINAL ANALGESIA
ETHISUXIMIDE BLOCKS Ca channels
VALPROIC ACID BLOCKS NA , GLUTAMATE , INHIBITS GABA TRANSAMINASE ,
Vigabatrin IRREVERSIBLE INHIBITOR OF GABA TRANSAMINASE
TIAGABINE INHIBIT GABA UPTAKE
TOPIRAMATE BLOCKS NA CHANNELS , INCREASES GABA , INHIBITS GLUTAMATE
LAMOTRIGINE DIRECTLY BLOCKS Na channel
FELBAMATE BLOCKS NMDA
TOLCAPONE COMT INHIB
ENTACAPONE Comt INHIB
AMANTADINE PREVENTS DOPAMINE UPTAKE AND FACILITATES PRESYNAPTIC RELEASE OF DA , BLOCKS NMDA , ANTI MUSCARINIC
SALBUTAMOL BETA BLOCKER. , TOCOLYTIC
TERBUTALINE BETA BLOCKER , TOCOLYTIC
NIFEDIPINE PERIPHERAL VASODILATOR , TOCOLYTIC
METYRAPONE 11 BETA HYDROXYLASE ENZYME INHIBITOR
AMINOGLUTETHAMIDE BLOCKS CONVERSION OF CHOLESTEROL TO PREGNENOLONE
MITOTANE
CLOMIPHENE SSRM , INCREASES FSH AND LH
TAMOXIFEN ANTAG OF ESTROGEN IN BREAST AND AG OF ESTROGEN IN UTERUS , BONE , PITUITARY , LIVER
DOLOXIFEN ANTAG OF ESTROGEN IN BREAST , AG IN BONE , LIVER , PITUITARY
TOREMIFEN ANTAG IN BREAST , AG IN BONE M LIVER , PITUITARY , UTERUS
FULVESTRANT ANTAG IN BREAST , AG IN BONE , LIVER , PITUITARY AND UTERUS
RALOXIFENE ANTIESTROGEN IN BREAST , ENDOMETRIUM , ESTROGEN IN BONE , COAGULATION OF BLOOD , LIPID META
CENTCHROMAN SERM
MIFEPRISTONE BLOCKS PROGESTERONE
GOSSYPOL REDUCES SPERM COUNT AND MOTILITY
ANASTROZOLE INHIBIT AROMATASE AND SO ESTROGEN
LETROZOLE INHIBIT AROMATASE AND SO ESTROGEN
FADROZOLE INHIBIT AROMATASE AND SO ESTROGEN
VOROZOLE INHIBIT AROMATASE AND SO ESTROGEN
LEVOTHYROXINE T4
CARBIMAZOLE INHIBITS THYROID PEROXIDASE , INCORPORATION OF IODINE INTO THE TYROSINE , AND INHIB OF COUPLING OF IODITYROSYL RESIDUES
METHIMAZOLE INHIBITS THYROID PEROXIDASE , INCORPORATION OF IODINE INTO THE TYROSINE , AND INHIB OF COUPLING OF IODITYROSYL RESIDUES
LUGOLS IODINE INCREASEDIODINE INHIBITS ITS OWN TRANSPORT AS WELL AS THE RELEASE OF THE HORMONE
PERCHLORATE COMPETITIVE INHIBITOR OF THYROIDAL IODINE TRANSPORT VIA THE Na/I TRANSPORTER
THIOCYANATE COMPETITIVE INHIBITOR OF THYROIDAL IODINE TRANSPORT VIA THE Na/I TRANSPORTER
INSULIN LISPRO ULTRA SHORT ACTING
INSULIN ASPARTAME ULTRA SHORT ACTING
INSULIN ZINC SUSPENSION /SEMILENTE SHORT ACTING
ISOPHANE INSULIN /LENTE INTERMEDIATE ACTING
INSULIN GLARGINE LONG ACTING
UKTRALENTE LONG ACTING
TOLBUTAMIDE BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN ulfonylurea
CHLORPROPAMIDE BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN sulfonylurea
REPAGLINIDE BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN meglitinide analogues
NATEGLINIDE BLOCKS K CHANNELS AND INCREASES CALCIUM AND HENCE STIMULATES B CELLS TO SECRETE INSULIN meglitinide
METFORMIN iNCREASES UPTAKE AND UTIKISATION OF GLUCOSE AND PREVENTS GLUCONEOGENESIS AND GLYCIGEN AND INCREASES BINDUNG OF INSUKIN TO ITS RECEPTOR , SLOWS GLUCOSE ABSORPTION FROM THE STOMACH, biguanids
PHENFORMIN iNCREASES UPTAKE AND UTIKISATION OF GLUCOSE AND PREVENTS GLUCONEOGENESIS AND GLYCIGEN AND INCREASES BINDUNG OF INSUKIN TO ITS RECEPTOR , SLOWS GLUCOSE ABSORPTION FROM THE STOMACH , biguanides
ACARBOSE Inhibits alpha gkycosidase and thus absorption of glucose
MIGLITO Inhibits alpha gkycosidase and thus absorption of glucose
ROSIGLITAZONE AGONIST TO PPAR GAMMA WHICH BINDS WITH RETINOID X RECEPTOR WHICH INCREASES LIPOGENESIS AND PROMOTES UPTAKE OF FATTY ACIDSAND GLUCOSE
PIOGLITAZONE AGONIST TO PPAR GAMMA WHICH BINDS WITH RETINOID X RECEPTOR WHICH INCREASES LIPOGENESIS AND PROMOTES UPTAKE OF FATTY ACIDSAND GLUCOSE
CODEINE CENTRALLY ACTING ANTITUSSIVE
DEXTROMETHORPHAN CENTRALLY ACTING ANTITUSSIVE
BENZONATATE INHIBITS PERIPHERAL RECEPTORS AND CENTRAL COUGH CENTRE AFFERENTS
PRENOXDIAZINE SUPRESSES PERIPHERAL RECEPTORS
AMMONIUM CHLORIDE STIMULATES BRONCHIAL CELLZ TI SECRETE MUCUS AND CIKIA TO CLEAR IT mucokinetic
SODIUM CITRATE STIMULATES BRONCHIAL CELLZ TI SECRETE MUCUS AND CIKIA TO CLEAR IT mucokinetic
ACETYL CYSTEINE MUCOLYTIC DECREASES VISCOSITY OF MUCUS BY SPLITTING DISULFIDE BONDS OF MUCOPROTEIN
BROMHEXINE DEPOLYMERISES MUCOPOLYSACCHARIDES OF MUCUS
DORNASE ALFA DNAase SPLITS DNA
SULFACYTINE ORAL , SHORT ACTING SULFONAMIDE
SULFADIAZINE ORAL , SHORT ACTING
SULFISOXOZOLE ORAL , SHORT ACTING
SULFAMETHAZOLE ORAL SHORT ACTING SULFONAMIDE
SULFAMETHAXOZOLE ORAL INTERMEDIATE ACTING SULFONAMIDE
SULFADOXINE ORAL LONG ACTING SULFONAMIDE
OLSALAZINE ORAL NON ABSORBABLE SULFONAMIDE
SILVER SULFADIAZINE TOPICAL SULFONAMIDE
SULFACETAMIDE TOPICAL SULFONAMIDE
NORFLOXACIN FIRST GENERATION FLUOROQUINOLONES
CIPROFLOXACIN FIRST GENERATION FLUOROQUINOLONES
OFLOXACILIN FIRST GENERATION FLUOROQUINOLONES
PEFLOXACIN FIRST GENERATION FLUOROQUINOLONES
LOMEFLOXACIN FIRST GENERATION FLUOROQUINOLONES
LEVOFLOXACIN SECOND GENERATION FLUOROQUINOLONES
GATIFLOXACIN THIRD GENERATION FLUOROQUINOLONES
SPARFLOXACIN THIRD GENERATION FLUOROQUINOLONES
MOXIFLOXACIN FOURTH GENERATION FLUOROQUINOLONES
ALATROFLOXACIN FOURTH GENERATION FLUOROQUINOLONES
TROVAFLOXACIN FOURTH GENERATION FLUOROQUINOLONES
PHENAZOPYRIDINE URINARY ANALGESIC ;
NITROFURANTOIN INHIBITS ACETYL COA WHICH BLOCKS CARB META AND SO THE BACTERIA ; URINARY ANTISEPTIC
NALIDIXIC ACID NON FLUORINATED QUINOLONES ; URINARY ANTISEPTICS
PENICILLIN V ORAL NATURAL PENICILLIN
PENICILLIN G IM OR IV NATURAL PENICILLIN
PROCAINE PENICILLIN IM DEPOT ; BETA LACTAMASE SENSITIVE
BENZATHINE PENCILLIN IM DEPOT ; BETA LACTAMASE PENICILLIN
CLOXACILLIN ORAL LACTAMASE RESISTANT PENICILLIN
DICLOXACILLLIN ORAL LACTAMASE RESISTANT PENICILLIN
METHICILLIN IM OR IV LACTAMASE RESISTANT PENICILLIN
CLAVULANIC ACID BETA LACTAMASE INHIBITOR ; BIND IRREVERSIBLY TO THE CATALYTIC SITE OF LACTAMASE
SULBACTAM BETA LACTAMASE INHIBITOR
TAZOBACTAM BETA LACTAMASE INHIBITOR
CEFAZOLIN FIRST GENERATION CEPALOSPORIN
CEFALOTHIN FIRST GENERATION CEPHALOSPORIN
CEFADROXIL FIRST GENERATION CEPHALOSPORIN
CEFARADINE FIRST GENERATION CEPHALOSPORIN
CEFUROXIME SECOND GENERATION CEPHALOSPORIN ORAL
CEFOXITIN SECOND GENERATION CEPHALOSPORIN PARENTERAL
CEFACLOR SECOND GENERATION CEPHALOSPORIN ORAL
CEFOTETAN SECOND GENERATION CEPHALOSPORIN PARENTERAL
CEFIXIME THIRD GENERATION CEPHALOSPORIN ORAL
CEFTIZOXIME THIRD GENERATION CEPHALOSPORIN PARENTERAL
CEFTRIAXONE THIRD GENERATION CEPHALOSPORIN PARENTERAL
CEFDINIR THIRD GENERATION CEPHALOSPORIN ORAL
CEFPODOXIME THIRD GENERATION CEPHALOSPORIN ORAL
CEFPEROME FOURTH GENERATION CEPHALOSPORIN PARENTERAL
CEFIPIME FOURTH GENERATION CEPHALOSPORIN PARENTERAL
AZTREONAM NEWER BETA LACTAM ANTIBIOTICS
CARBAPENEM NEWER BETA LACTAM
VANCOMYCIN INHIBITS GRAM POSITIVE CELL WALL SYNTHESIS BY COMPLEXING D ALANYL D ALANINE PORTION OF TERMINAL END OF PEPTIDOGLYCAN
TEICOPLANIN INHIBITS GRAM POSITIVE CELL WALL SYNTHESIS BY COMPLEXING WITH D ALANYL D ALANINE PORTION OF THE TERMINAL END OF THE PEPTIDOGLYCAN
BACITRACIN BLOCKS THE FUNCTION OF LIPID CARRIER MOLECULES WHICH TRANSFERS CELL WALL SUBUNITS ACROSS CELL MEMBRANE
FOSFOMYCIN INHIBITS BACTERIAL CELL WALL SYNTHESIS BY INACTIVATING PYRUVYL TRANSFERASE WHICH IS CRUCIAL FOR THE FORMATION OF UDP N ACETYL MURAMIC ACID WHICH IS FOUND IN THE CELL WALL
STREPTOMYCIN AMINOGLYCOSIDE
GENTAMYCIN AMINOGLYCOSIDE
KANAMYCIN AMINOGLYCOSIDE
AMIKACIN AMINOGLYCOSIDE
NEOMYCIN AMINOGLYCOSIDE , TOPICAL
SOFRAMYCIN AMINOGLYCOSIDE TOPICAL
PAROMOMYCIN AMINOGLYCOSIDE , TOPICAL
ERYTHROMYCIN MACROLIDE
ROXITHROMYCIN MACROLIDE
CLARITHROMYCIN MACROLIDE
AZITHROMYCIN MACROLIDE
SPIRAMYCIN MACROLIDE
CLINDAMYCIN LINCOSAMIDE
TELITHROMYCIN KETOLIDE
LINEZOLID OXAZOLIDINONE
PRISTINNAMYCIN COMBI OF STREPTOGRAMIN B AND STREPTOGRAMIN A IN A 30 : 70 RATIO ; BINDS TO 50S ( STREPTOGRAMINS)
POLYMYXIN B DISRUPTS THE BACTERIAL CELL MEMBRANE OSMOTIC INTEGRITY BY DISPLACING CALCIUM AND MAGNESIUM FROM MEMBRANE LIPID PHOSPHATES
MUPIROCIN INHIBITS BACTERIAL RNA AND PROTEIN SYNTHESIS BY BINDING TO ISOLEUCYL T RNA SYNTHETASE
FUSIDIC ACID INHIBITS PROTEIN ELONGATION
TETRACYCLINE
CHLORAMPHENICOL
DOXYCYCLINE TETRACYCLINE
DEMECLOCYCLINE TETRACYCLINE
MINOCYCLINE TETRACYCLINE
ISONIAZID INHIBITS SYNTHESIS OF MYCOLIC ACID WHICH IS AN ESSENTIAL COMPONENT OF MYCOBACTERIAL CELL WALL
RIFAMPICIN BINDS STRONGLY TO THE BETA SUBUNIT OF BACTERIAL DNA DEPENDENT RNA POLYMERASE , SO INHIBITS RNA SYNTHESIS
ETHAMBUTOL INHIBITS ARABINOSYL TRANSFERASE ENZYME TO PREVENT POLYMERISATION OF ARABINOGLYCANS IN MYCOBACTERIAL CELL WALL
PYRAZINAMIDE IT ENTERS THE MYCOBACTERIUM AND GETS CONVERTED TO PYRAZINOIC ACID BY BACTERIAL PYRAZINAMIDASE WHICH INHIBITS MYCOBACTERIAL FATTY ACID SYNTHASE I AND DISRUPTS MYCOLIC ACID FORMATION
DAPSONE INHIBITION OF BACTERIAL FOLIC ACID SYNTHESIS
CLOFAZIMINE BINDS TO THE MYCOBACTERIAL DNA , INTERFERES WITH ITS TEMPLATE FUNCTION AND INHIBITS MYCOBACTERIAL GROWTH
ACLOMETASONE TOPICAL GLUCOCORTICOID
AMCINONIDE TOPICAL GLUCOCORTICOID
BELCOMETHASONE TOPICAL/INHALATIONAL GLUCOCORTICOID
BUDESOINDE INHALATIONAL GLUCOCORTICOID
FLUCINOLONE TOPICAL GLUCOCORTICOID
FLUTICASONE TOPICAL GLUCOCORTICOID
MEDRYSONE OPTHALMIC GLUCOCORTICOID
LEVOTHYROXINE SODIUM INCREASES T4 TO T3 AND REDUCES TSH STIMULATION BY NEGATIVE FEEDBACK AND THUS CAN BE USED IN NON ENDEMIC GOITRE ; ALSO USED IN REFRACTORY ANAEMIAS , NON HEALING WOUNDS , CHRONIC CONSTIPATION , MENSTRUAL DISORDERS AND INFERTILITY
LIOTHYRONINE NOT USED AS MUCH ; MYXOEDEMA COMA , SHORT TERM SUPRESSION OF TSH IN THYROIDECTOMY ,
PROPYLTHIOURACIL INHIBIT PEROXIDASE , COUPLING , INCORPORATION OF IODINE INTO TYROSYL RESIDUES , AND PERIPHEARL CONVERSION OG T4 TO T3
CARNBIMAZOLE INHIBIT PEROXIDASE , COUPLING , INCORPORATION OF IODINE INTO TYROSYL RESIDUES , AND PERIPHEARL CONVERSION OG T4 TO T3
METHCARBIMAZOLE INHIBIT PEROXIDASE , COUPLING , INCORPORATION OF IODINE INTO TYROSYL RESIDUES , AND PERIPHEARL CONVERSION OG T4 TO T3
RADIOACTIVE IODINE EVALUATING THYROID FUNCTIONS , NON SURGICAL THYROID ABLATION , BETA PARTICLES DESTROY PARENCHYMA
LUOGOLS IODINE LIMITS ITS OWN TRANSPORT , THYROID HORMONE RELEASE , ; PREPARE PATIENT FOR THYROIDECTOMY , BY MAKING IT LESS VASCULAR AND MORE COMPACT ; TREAT SEVERE THYROTOXICOSIS
PERCHLORATE ION COMPETITIVE INHIBITOR OF THYROIDAL IODIDE TRANSPORT VIA NA , I TRANSPORTER . RARELY USED CUZ IT CAUSES FATAL APLASTIC ANAEMIA AND GASTRIC ULCERS
THIOCYANATE COMPETITIVE WITH THE IODIDE TRANSPORTER
ORAL IPODATE HYPERTHYROID , INHIBIT 5 DEIODINASE AND PREVENT CONVERSION OF T4 TO T3
CASPOFUNGIN INHIBITS CELL WALL SYNTHESIS
AMPHOTERICIN B MACROLIDE , BINDS TO ERGOSTEROL , HENCE FORMING PORES CAUSE LEAKING OF IONS AND FURTHER LYSIS
NYSTATIN BINDS TO ERGOSTEROL AND HENCE FORMS PORES CAUSING LEAKING OF IONS AND FURTHER LYSIS
TERBINAFINE INHIBITS LANOSTEROL TO ERGOSTEROL BY SQUALENE EPOXIDASE , RESULTING IN ACC OF SQUALENE CAUSING LYSIS
NAFTIFINE INHIBITS LANOSTEROL TO ERGOSTEROL CAUSING LYSIS
BUTENAFINE INHIBITS LANOSTEROL TO ERGOSTEROL CAUSING LYSIS
MICONAZOLE BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
KETOCONAZOLE BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
FLUCONAZOLE BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
ITRACONAZOLE BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
VORICONAZOLE BINDS TO FUNGAL CYTOCHROME P 450 WHICH PREVENTS THE CONVERSION OF LANOSTEROL TO ERGOSTEROL BY 14 ALPHA DEMETHYLASE
GRISEOFULVIN INTERACTS WITH POLYMERISED MICROTUBULES CAUSING DISRUPTION
TERBINAFINE
Created by: manjari