Antihipertensive
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each of the black spaces below before clicking
on it to display the answer.
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Clase de AntiHTA | Simpatolitice, blocante de Ca, Diuretice, VD, Inhib Izo
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Simpatolitice (medicamente) - inhib simp prin act centrala | clonidina, metildopa, moxonidina
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Ganglioplegice (medicament - mecanism) | antagonisti competitivi (cu acth) pe receptorii nicotinici -> trimetafanul (disectie de aorta , hta urgente)
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Blocante ale terminatiilor simpatice (medicamente) | guanitidina, rezerpina
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Mecanisme guanitidina si rezerpina | g - scade captarea CA din fanta (TA creste putin dupa care scade mult) , r - scade captarea na, dopa, ser in granule
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Blocante alfa adrenergice (medicamente) | neselective: fentolamine, tolazolina (feocromocitom)....selective alfa1: prazosin , terazosin,doxazosin
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VD | hidralazina, minoxidil, diazoxid, nitroprusiatul de sodiu(RA: methemoglobinemie)
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Reactii adverse VDuri | hidralazina ( polinevrite periferice, sdr.lupoid, anemie, leucopenie, trombocitopenie), minoxidil ( retentie hidrosalina majora si
hipertricoza) , diazoxid (efect hiperglicemiant (ca diureticele de tip tiazidic!!!) prin scaderea secretiei de insulina)
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Blocante de Ca | dihidropiridine: nife, amlo, felo,nicardipina
benzodiazepine: diltiazem
fenilalchilamine: verapamil
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Mecanisme blocante Ca | DHP- VD perif cu tahicardie reflexa
benzo + fenil : deprimare cord -> scad DC -> scad TA
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IEC | captopril, enalapril, lisinopril
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