Davis Slides
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Name the four cardinal sign of inflammation | Redness
Heat
Pain
Swelling
🗑
|
||||
| Steroids block the inflammatory process where | Arachidonic acid
🗑
|
||||
| NSAIDs block where | The COX cycle into the prostaglandins
🗑
|
||||
| How do Steroids work | ARACHNOID ACID
Block the production of inflammatory agents
Decrease dilation and permeability of vessels
Decrease WBC proliferation and mast cell degranulation ( Allergic response)
🗑
|
||||
| Name two inflammatory agents | Prostaglandins
Inflammatory mediators
🗑
|
||||
| Name three inflammatory mediators | Cytokines
Leukotrienes
complement
🗑
|
||||
| What are the SYSTEMIC side effects/ Complication of steroids | stomach ulcers
more susceptible to infections-herpes
mask underlying disorders
delay wound healing
psychoses
moon face
muscle and bone weakness
growth retardation in children
🗑
|
||||
| How do you discontinue steroid Rx | Taper- Gradually
🗑
|
||||
| What are the main ocular side effects of steroids? | posterior sub-capsular cataract (PSC)
Increased in IOP
Reactivate herpes
🗑
|
||||
| Is PSC (posterior sub-capsular cataract)Reversible? | No
🗑
|
||||
| **Increased IOP due to steroids** | More common in patients with Glaucoma
may Raise as high as 10mm Hg
Generally reversible after 1-3 weeks
🗑
|
||||
| What are two forms of prednisolone gtts? Which one is stronger? | Acetate-strongest
Phosphate
🗑
|
||||
| What is the strongest and most effective topical steroid? | Difluprednate
*perdnisolone is the next strongest
🗑
|
||||
| Which is the least effective and weakest topical steroid? | Medrysone
🗑
|
||||
| Which topical steroid have the most and strongest side effects and which have to least? | Strongest- Difluprednate, prednisone acetate, Dexamthasone
Weakest- Medrysone weakest- Fluorometholone
🗑
|
||||
| Steroids combined with what are frequently used to treat blepharitis and OSD? | Antibiotics
🗑
|
||||
| Name ocular disorders topical steroids commonly used to treat? | Blepharitis and OSD
severe allergic blepharitis
Phlyctentules
stromal herpes simplex
herpes zoster (Shingles)
corneal transplant immune reactions
post-operative cataract and glaucoma surgeries
uveitis
sclerities
chemical burns
🗑
|
||||
| Name SYSTEMIC ocular disorders treated with steroids | Optic Neuritis
Temporal Arteritis (Giant Cell Arterities-GCA)
Graves Ophthalmopathy
🗑
|
||||
| Intravitreal steroids are used for? | CSME in diabetes, Vascular occlusion, WET ARMD
🗑
|
||||
| The body produces antibodies in response to what? | Antigens
🗑
|
||||
| What are Antigens? | Any substance that stimulates production of antibodies.
🗑
|
||||
| Anti-histamines block the allergic response where? | H-1 receptor site
🗑
|
||||
| Mast cell stabilizers act by during what? | Preventing granulation of Mast cells
🗑
|
||||
| Mast cell deanulation produce what? | Histamine, Cytokins, and prostaglandins
🗑
|
||||
| The lowest level of treatment of allergic conjunctivitis is what? | Astringents, AF, and other OCULAR Decongestants
🗑
|
||||
| Mild allergic conjunctivitis is treated how? | Antihistamines
🗑
|
||||
| Moderate allergic conjunctivites is treat with what? | Combination: antihistamines and mast cells stabilizers
🗑
|
||||
| Name some of the ocular decongestants | Phenylephrine 1/8%, Naphazoline 1/8%, Tetrahydrozoline 1/8%
🗑
|
||||
| What is the weakest decongestant? | Phenylephrine
🗑
|
||||
| Name three mast cell stab/anti-histamine drugs | Olpatadines, Ketotifens, Bepotastine
🗑
|
||||
| Which combination drug (mast cell stab/anti-histamine) is OTC | Ketotifens
🗑
|
||||
| Name a good anti-histamine? | Alcaftadine- works in minutes and last up to 16hrs
🗑
|
||||
| When a drug has '-A' at the end what kind is it? | Decongestant with antihistamine
🗑
|
||||
| what do you tell patients about the use of Anti-histamines | stings
dry eye
use for short time, because of rebound
🗑
|
||||
| pure mast cells destabilizes are primary use for what and how long does it take to be effective? | vernal conjunctives and Giant papillary conjunctives-4 weeks
🗑
|
||||
| what are the side effects of pure mast cells destabilizes? | Unpleasant taste, cough, runny nose, throat irritation
🗑
|
||||
| what is vernal keratoconjunctities? what are it's sign and symptoms? | Severe form of allergic conjunctivitis. GPC & phlctentules
🗑
|
||||
| what is atopic keratoconjunctivites | form of allergic skin lesions with ocular symptoms.
🗑
|
||||
| What are the anti-VEGF drugs used for? Name them | CSME in diabetes
wet ARMD
Vadcular occlusion
to treat neovascularization
🗑
|
||||
| Name the anti-VEGF drugs | ranibizumab
bevacizumab
aflibercept
🗑
|
||||
| what three drugs are used to treat Retinal/choroidal diagnosis? | fluoroscein
Indocyanine green
Infracyanine green
🗑
|
||||
| WHAT IS THE DIFFERENCE BETWEEN Indocyanine Green AND Infracyanine Green | Indocyanine Green AND Infracyanine Green- USED IN THE CHOROID
Infracyanine Green- DOES NOT HAVE IODINE
🗑
|
||||
| WHAT DRUG IS INJECTED INTRAVITREAL FOR CSME | STEROIDS
🗑
|
||||
| WHAT DRUG IS USED FOR PDT | VERTEPORFIN
🗑
|
||||
| WHAT DRUG IS USED TO STAIN THE ANTERIOR CAPSULE AND MACULAR MEMBRANES? | METHYLENE BLUE
🗑
|
||||
| WHAT ARE THE SIGNS OF DRY ARMD | ATROPHY AND PIGMENTARY CHANGES OF THE RPE AND RETINA, LARGE SOFT DRUSEN
🗑
|
||||
| TERMS OF DRUGS AFFECTING THE SYMPATHETIC NS | ADRENERGIC
🗑
|
||||
| TERMS OF DRUGS AFFECTING THE PARASYMPATHETIC NS | CHOLINERGIC
🗑
|
||||
| TERMS WHICH MEANS STIMULATE OR INCREASE THE ACTION | AGONIST
MIMETIC
🗑
|
||||
| TERMS WHICH MEAN INHIBIT OR STOP THE ACTION | ANTAGONIST
BLOCKER
LYIC
🗑
|
||||
| YOU CAN GET ESSENTIALLY THE SAME EFFECT IF SYMPATHOMIMETIC DRUGS BY USING WHAT KIND OF DRUGS | PARASYMATHOLYIC
🗑
|
||||
| WOULD THE EFFECTS OF A SYMPATHOMIMTIC DRUG AND A PARASYMATHOLYTIC BE THE SIMILAR OR DIFFERENT? | SIMILAR
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
Orange15
Popular Pharmacology sets