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Psychiatric drugs

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Drug
Info
Side effects
Citalopram   SSRI. Depression and panic disorder. Causes long QT.   Mainly N&V. SSRI+NSAID=prescribe a PPI. Can increase anxiety initially. Sexual dysfunction.  
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Fluoxetine   SSRI. Depression. Better for young patients. Long half life. Higher incidence of drug interactions.   Mainly N&V. SSRI+NSAID=prescribe a PPI. Can increase anxiety initially. Sexual dysfunction.  
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Sertraline   SSRI. Depression. Better in ischaemic heart disease. First line in GAD.   Mainly N&V. SSRI+NSAID=prescribe a PPI. Can increase anxiety initially. Sexual dysfunction.  
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Paroxetine   SSRI. Depression and PTSD. Higher incidence of drug interactions. Higher incidence of withdrawal symptoms.   Mainly N&V. SSRI+NSAID=prescribe a PPI. Can increase anxiety initially. Sexual dysfunction.  
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Venlafaxine   SNRI. Depression and social phobia.   Chills, anorexia, nausea, agitation, dizziness, tremor.  
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Mirtazapine   NaSSA. Depression, and 1st line for PTSD.   Constipation, dry mouth, weight gain, somnolence.  
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Amitryptiline   TCA- Sedative. Mainly neuropathic pain and migraine prophylaxis. Very toxic in overdose.   Drowsiness, dry mouth, blurred vision, constipation, urinary retention.  
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Dosulepin   TCA- Sedative. Mainly neuropathic pain and migraine prophylaxis. Very toxic in overdose.   Drowsiness, dry mouth, blurred vision, constipation, urinary retention.  
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Trazodone   TCA- Sedative. Mainly neuropathic pain and migraine prophylaxis.   Drowsiness, dry mouth, blurred vision, constipation, urinary retention.  
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Imipramine   TCA- Less sedative. Mainly neuropathic pain and migraine prophylaxis.   Dry mouth, blurred vision, constipation, urinary retention.  
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Nortriptyline   TCA- Less sedative. Mainly neuropathic pain and migraine prophylaxis.   Dry mouth, blurred vision, constipation, urinary retention.  
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Lofepramine   TCA- Less sedative. Mainly neuropathic pain and migraine prophylaxis. Least toxic in overdose.   Dry mouth, blurred vision, constipation, urinary retention.  
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Chlorpromazine   Typical antipsychotic.   EPSE's. Antimuscarinic effects. Sedating effects. Hyperprolactinaemia.  
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Haloperidol   Typical antipsychotic. Has a depo form. Prolonged QT syndrome.   EPSE's. Antimuscarinic effects. Sedating effects. Hyperprolactinaemia. Prolongs QT interval  
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Flupentixole   Typical antipsychotic. Has a depo form.   EPSE's. Antimuscarinic effects. Sedating effects. Hyperprolactinaemia.  
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Fluphenazine   Typical antipsychotic. Has a depo form.   EPSE's. Antimuscarinic effects. Sedating effects. Hyperprolactinaemia.  
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Olanzepine   Atypical antipsychotic.   EPSE's, but less so than typicals. Weight gain, neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts.  
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Risperidone   Atypical antipsychotic. Has a depo form.   EPSE's, but less so than typicals. Weight gain, neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts.  
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Amisulparide   Atypical antipsychotic.   EPSE's, but less so than typicals. Weight gain, neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts.  
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Quetiapine   Atypical antipsychotic.   EPSE's, but less so than typicals. Weight gain, neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts.  
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Aripiprazole   Atypical antipsychotic. Less weight gain and sedation. Insomnia and akathisia is worse.   EPSE's, but less so than typicals. Neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts. NO WEIGHT GAIN or sedation., but insomnia and akathisia more pronounced.  
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Clozapine   Atypical antipsychotic. NOT 1st LINE. AGRANULOCYTOSIS (1%) and neutropenia (3%).   EPSE's, but less so than typicals. Weight gain, neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts. AGRANULOCYTOSIS 1%, and neutropenia 3%.  
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Lithium   Mood stabiliser   Weight gain, Leukocytosis, Polyuria/polydypsia, tremor, Headache, Decreased memory, Confusion, N&V, Muscle twitch, Hyperreflexia, Vertigo. Can cause hypothyroidism and hair thinning.  
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Sodium valproate   Mood stabiliser   Tiredness, tremors, nausea, vomiting and sedation.  
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Olanzepine   Mood stabiliser   EPSE's, but less so than typicals. Weight gain, neuroleptic malignant syndrome, tardive dyskinesia. Stroke and VTE in older pts.  
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Carbamazepine   Mood stabiliser   Drowsiness, dizziness, headaches and migraines, motor coordination impairment, nausea, vomiting and/or constipation. Can cause cardiac arrhythmias, aplastic anemia or agranulocytosis.  
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