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Hepatitis B/C Drugs

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Class/MOA
Generic
Brand
Route
Side Effects
Hep B/C
NS3/4 Protease Inhibitor   Telaprevir   Incivek   po   rash pruritus, anemia, fatigue, n/v/d, dysgeusia, anorectal irritaion/itching   C  
🗑
NS3/4 Protease Inhibitor   Simepravir   Olysio   po   rash/photosensitivity, pruritus, nausea   C  
🗑
NS5B Polymerase Inhibitor   Sofosbuvir   Sovaldi   po   fatigue, HA, nausea, insomnia   C  
🗑
  Adefovir   Hepsera     renal dysfucntion   B  
🗑
  Entecavir   Baraclude     n/v, dizziness, headache, fatigue   B  
🗑
  Tenofovir   Viread     potentially renal, well tolerated   B (DOC)  
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  Telbivudine   Tyzeca     nausea, ab pain, ha, urti, malaise, fatigue, increased cpk    
🗑
pegylated interferon (immune stimulation)   peginterferon alpha-2a   Pegasys   inj   depression, suicide, flu-like illnesses, weight loss, bone marrow depression   B/C  
🗑
pegylated interferon (immune stimulation)   peginterferon alpha-2b   Pegintron   inj   depression, suicide, flu-like illnesses, weight loss, bone marrow depression   B/C  
🗑
MOA Unknown   Ribavirin   Ribavirin   po   bone marrow suppression, anemia, n/v, diarrhea, birth defects/death of unborn child, mitochondrial toxicity   C  
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NS3/4 Protease Inhibitor   Bocepravir   Victrelis   po   anemia, neutropenia, nausea, dysgeusia, diarrhea, vomiting, chills   C  
🗑
  Lamivudine       ear, nose, throat infections   B  
🗑


   

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