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Hepatitis B/C
Hepatitis B/C Drugs
| Class/MOA | Generic | Brand | Route | Side Effects | Hep B/C |
|---|---|---|---|---|---|
| NS3/4 Protease Inhibitor | Telaprevir | Incivek | po | rash pruritus, anemia, fatigue, n/v/d, dysgeusia, anorectal irritaion/itching | C |
| NS3/4 Protease Inhibitor | Simepravir | Olysio | po | rash/photosensitivity, pruritus, nausea | C |
| NS5B Polymerase Inhibitor | Sofosbuvir | Sovaldi | po | fatigue, HA, nausea, insomnia | C |
| Adefovir | Hepsera | renal dysfucntion | B | ||
| Entecavir | Baraclude | n/v, dizziness, headache, fatigue | B | ||
| Tenofovir | Viread | potentially renal, well tolerated | B (DOC) | ||
| Telbivudine | Tyzeca | nausea, ab pain, ha, urti, malaise, fatigue, increased cpk | |||
| pegylated interferon (immune stimulation) | peginterferon alpha-2a | Pegasys | inj | depression, suicide, flu-like illnesses, weight loss, bone marrow depression | B/C |
| pegylated interferon (immune stimulation) | peginterferon alpha-2b | Pegintron | inj | depression, suicide, flu-like illnesses, weight loss, bone marrow depression | B/C |
| MOA Unknown | Ribavirin | Ribavirin | po | bone marrow suppression, anemia, n/v, diarrhea, birth defects/death of unborn child, mitochondrial toxicity | C |
| NS3/4 Protease Inhibitor | Bocepravir | Victrelis | po | anemia, neutropenia, nausea, dysgeusia, diarrhea, vomiting, chills | C |
| Lamivudine | ear, nose, throat infections | B |