Pharmacologie des sympathomimétiques
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7 actions sympathomimétiques des catécholamines? | 1. Excitation périph. muscles lisses (vaiss. sguin)
2.Inhibition périph muscles lisses (TGI, bronches)
3. Excitation cardiaque
4. Actions métaboliques (^glycogénolyse)
5. Action endocrino (modulation insuline)
6. Action SNC
7. Action présynaptique
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Sympathomimétiques (6) | * Catécholamine endogène * Agoniste B-adr * Agoniste B2-adr * Agoniste alpha1-adr * Agoniste alpha2-adr * Agonistes divers
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Exemple catécholamine endogènes (3) | Ep, NE, DA
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2 agonistes beta-adrénergiques (2) | isoproterenol, dobutamine
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2 agonistes beta2-adrénergiques (2) | Salmétérol, Salbutamol
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Agoniste alpha 1-adrénergique (1) | Phényléphrine
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Agonistes alpha 2-adrénergiques (1) | Clonidine
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Agonistes sympathomimétiques divers (3) | Amphétamines, Éphedrine, Oxymetazoline
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Application thérapeutique des sympathomimétiques (9) | 1. Tx choc hypovolémique/cardiogénique/distributif
2. Arrêt cardiaque
3. Hypo/Hyper tension (alpha 2)
4. Insuff. cardiaque
5. Décongestion nasale
6. Asthme/MPOC
7. TDAH
8. Narcolepsie
9. Obésité
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