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Pharmaco sympathomim

Pharmacologie des sympathomimétiques

7 actions sympathomimétiques des catécholamines? 1. Excitation périph. muscles lisses (vaiss. sguin) 2.Inhibition périph muscles lisses (TGI, bronches) 3. Excitation cardiaque 4. Actions métaboliques (^glycogénolyse) 5. Action endocrino (modulation insuline) 6. Action SNC 7. Action présynaptique
Sympathomimétiques (6) * Catécholamine endogène * Agoniste B-adr * Agoniste B2-adr * Agoniste alpha1-adr * Agoniste alpha2-adr * Agonistes divers
Exemple catécholamine endogènes (3) Ep, NE, DA
2 agonistes beta-adrénergiques (2) isoproterenol, dobutamine
2 agonistes beta2-adrénergiques (2) Salmétérol, Salbutamol
Agoniste alpha 1-adrénergique (1) Phényléphrine
Agonistes alpha 2-adrénergiques (1) Clonidine
Agonistes sympathomimétiques divers (3) Amphétamines, Éphedrine, Oxymetazoline
Application thérapeutique des sympathomimétiques (9) 1. Tx choc hypovolémique/cardiogénique/distributif 2. Arrêt cardiaque 3. Hypo/Hyper tension (alpha 2) 4. Insuff. cardiaque 5. Décongestion nasale 6. Asthme/MPOC 7. TDAH 8. Narcolepsie 9. Obésité
Created by: Veri



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