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Hypertension Meds

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Term
Definition
Diuretics   increase urine output by inhibiting sodium and water reabsorption by the kidneys  
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Thiazide and Thiazide-like Diuretics   Increase urine output by promoting sodium, chloride, and water excretion. Also causes loss of sodium potassium, and magnesium. Calcium saved .  
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Loop Diuretics   Act on the loop of Henle to cause sodium and water loss. Also causes loss of potassium, magnesium, and calcium.  
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Potassium-Sparing Diuretics   Mild Diuretic. Promote sodium and water excretion and potassium retention by the kidney.  
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Beta Blockers   Decrease sympathetic nervous system response, resulting in decreased BP, HR, contractility, CO, and renin activity.  
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Alpha Blockers   Block effects of sympathetic nervous system on smooth muscle of blood vessels, resulting in vasodilation and decreased BP.  
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Combined Alpha and Beta Blockers   Block alpha-adrenergic receptors, causing vasodilation and reduced BP.  
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Central Acting Alpha Agonists   Block effects of sympathetic nervous system centrally.  
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ACE Inhibitors   Blocks production of angiotensin II, a potent vasoconstrictor. Reduces peripheral arterial resistance and BP.  
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Angiotensin II Receptor Antagonists (ARB)   Block angiotensin II receptors causing vasodilation and reduction in BP.  
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Aldosterone Receptor Antagonist   Blocks binding of aldosterone at receptor site to reduce sodium reabsorption and then BP.  
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Calcium Channel Blockers   Prevent movement of extracellular calcium into the cell which vasodilates.  
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Direct Vasodilators   Relax smooth muscles of blood vessels, causing vaodilation and decreased BP.  
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Examples of Thiazide Diuretics   Hydrochlorothiazide (HYDRODIURIL) Chlorothiazide (DIURIL)  
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Examples of Thiazide-Like Diuretics   Chlorothalidone (HYGROTON) Indapamide (LOZOL) Metolazone (ZAROXOLYN)  
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Examples of Loop Diuretics   Bumetanide (BUMEX) Furosemide (LASIX) Torsemide (DEMADEX)  
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Examples of Potassium-Sparing Diuretics   Amiloride (MIDAMOR) Spironolactone (ALADACTONE)  
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Examples of Beta Blockers   Atenolol (TENORMIN) Metoprolol (LOPRESSOR) Nadolol (CORGARD) Propranolol (INDERAL)  
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Examples of Alpha Blockers   Prazosin (MINIPRESS) Terazosin (HYTRIN)  
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Examples of Combined Alpha and Beta Blockers   Carvedilol (COREG) Labetalol (NORMODYNE)  
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Examples of Central Acting Alpha Agonists   Clonidine (CATAPRES) Guanfacine (TENEX) Methyldopa (ALDOMET)  
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Examples of ACE Inhibitors   Benazepril (LOTENSIN) Captopril (CAPOTEN) Enalapril (VASOTEC) Fosinopril (MONOPRIL) Lisinopril (PRINIVIL, ZESTRIL) Moexipril (UNIVASC) Perindopril (ACEON) Quinapril (ACCUPRIL) Ramipril (ALTACE) Trandolapril (MAVIK)  
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Examples of of Angiotensin II Receptor Antagonists   Candesartan (ATACAND) Eprosartan (TEVETEN) Irbesartan (AVAPRO) Lossartan (COZAAR) Olmesartan (BENICAR) Telmisartan (MICARDIS) Valsartan (DIOVAN)  
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Examples of Aldosterone Receptor Antagonist   Eplerenone (INSPRA)  
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Examples of Calcium Channel Blockers   Amlodipine (NORVASC) Diltiazem (CARDIZEM) Felodipine (PLENDIL) Isradipine (DYNACIRC) Nifedipine (PROCARDIA) Nisoldipine (SULAR) Verapamil (CALAN, ISOPTIN)  
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Examples of Direct Vasodilators   Hydralazine (APRESOLINE) Minoxidil (LONITEN)  
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