Autonomic Nervous System
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Cholinergic receptors | Acetylcholine
Muscarinic
Nicotinic
🗑
|
||||
| Muscarinic | located on parasympathetic postganglionic synapses and the sympathetic postganglionic synapses in sweat glands
🗑
|
||||
| nicotinic | located on presynaptic ganglia of the sympathetic and parasympathetic nervous system
🗑
|
||||
| Adrenergic receptors | Alpha
Beta
Dopamine
🗑
|
||||
| Direct Acting Cholinergic | Carbachol and Pilocarpine
Bethanecol
Nictoine
a lot of side effects
🗑
|
||||
| Carbachol (Isopto Carbachol) | Nicotinic and mucarinic
Opthalmic agent, resistant to cholinesterase treats glaucoma- reduce intraocular pressure by pupillary constriction and ciliary muscle activation
🗑
|
||||
| Bethanecol (Urecholine) | mostly muscarinic
increases GI and urinary tract tone
relaxes sphincters. atonic pts
orally or subcutaneously
can be given systemically and longer lasting
🗑
|
||||
| Nicotine (Nicorette) | replacement for smoking cessation
drug of abuse
🗑
|
||||
| Cholinesterase Inhibitors | Neostigmine
Pyridostigmine
Edrophonium
Physostigmine
Donepezil
Galantamine
rivastigmine
🗑
|
||||
| Neostigmine (Prostigmin) | nicotinic and muscarinic
partial neuromuscular nicotinic receptor agonist* anesthesiology
🗑
|
||||
| Pyridostigmine (Mestinon) | muscarinic and nicotinic
reversal of neuromuscular blockade after general anesthesia
🗑
|
||||
| Edrophonium (Tensilon) | muscarinic and nicotinic
reversal of neuromuscular blockade after general anesthesia
🗑
|
||||
| Physostigmine | muscarinic and nicotinic
reversal of anticholinergic induced toxicity
🗑
|
||||
| Donepezil (Aricept) | Help decrease the the symptoms of Alzheimers and delay memory loss
🗑
|
||||
| Galantamine (Reminyl) | Help decrease the the symptoms of Alzheimers and delay memory loss
🗑
|
||||
| Rivastigmine (Exelon) | Help decrease the the symptoms of Alzheimers and delay memory loss
🗑
|
||||
| Anticholinergic Agents- Muscarinic Blockers | Benztropine
Scopolamine
Atropine
Dicyclomine
Glycopyrrolate
Oxybutinin
Tolterodine
Ipratropium
🗑
|
||||
| Benztropine (Cogentin) | reduce tremor, muscle rigidity, used in treating psychosis
🗑
|
||||
| Scopolamine | motion sickness, vertigo
🗑
|
||||
| Atropine** | inhibits accommodation and causes pupillary dilation- glaucoma
Resuscitation for symptomatic bradycardia
🗑
|
||||
| Dicyclomine (Bentyl) | slows peristalsis, decrease hypermotility treating IBS
🗑
|
||||
| Glycopyrrolate (Robinul) | reduce secretions and decrease salivation
🗑
|
||||
| Oxybutinin (Ditropan) | GU- decreases bladder tonicity, urge incontinence, bladder spasm
🗑
|
||||
| Tolterodine (Detrol) | GU- decreases bladder tonicity, urge incontinence, bladder spasm
🗑
|
||||
| Ipratropium (Atrovent) | reverse bronchospasm in asthmatics
🗑
|
||||
| Anticholinergic agents- Nicotinic blockers | Succinylcholine
Tubocurarine
Vecuronium
🗑
|
||||
| Succinylcholine (Anectine) | depolarizing agents- bind and activate but dont dissociate. no muscle contraction, paralysis
🗑
|
||||
| Tubocurarine | non-depolarizing agents- block the receptor without activating it. flaccid paralysis
🗑
|
||||
| Vecuronium (Norcuron) | most commonly used for flaccid paralysis. takes a few minutes
🗑
|
||||
| Alpha 1 agonists | phenylephrine
oxymetazoline
found on vascular and smooth muscle
Midodrine
🗑
|
||||
| Phenylephrine (Neo-synephrine) | nasal decongestant, systemic vasoconstrictor
🗑
|
||||
| Oxymetazoline (Afrin) | nasal decongestant
🗑
|
||||
| Midodrine (ProAmatine) | systemic vasoconstrictor used to treat orthostatic hypotension
🗑
|
||||
| Alpha 2 Agonists | Clonidine
Methyldopa
Tizanidine
Brimonidine
on presynaptic terminal
🗑
|
||||
| Clonidine (Catapres) | antihypertensive- decrease release of neurotransmitter
🗑
|
||||
| Methyldopa (Aldomet) | antihypertensive- decrease release of neurotransmitter
🗑
|
||||
| Tizanidine (Zanaflex) | decrease muscle tone to treat spasticity
🗑
|
||||
| Brimonidine (Alphagan) | decreases intraocular pressure by decreasing vitreous production for glaucoma
🗑
|
||||
| Alpha Blockers (Alpha 1) | Doxazosin
Phentolamine
Terazosin
Tamsulosin
🗑
|
||||
| Doxazosin (Cardura) | mild anti hypertensive. vasodilate
🗑
|
||||
| Phentolamine (Regitine) | potent alpha blocker used prior to surgery of pheochomocytoma. vasodilator. IV
🗑
|
||||
| Terazosin (Hytrin) | ureteral dilation for prostate. BPH and Kidney stone
🗑
|
||||
| Tamsulosin (Flomax) | ureteral dilation. BPH and Kidney stone
🗑
|
||||
| Nonspecific Adrenergic agonists | Epinephrine
Norepinephrine
Amphetamine
🗑
|
||||
| Epinephrine (Adrenaline) | stimulates all receptors
vasoconstrictive for anaphylaxis (alpha) Bronchodilatory (beta 2) Cardiostmulatory (beta 1)
vasoconstriction and cardiac stim for cardiac arrest
added to local anesthetics for decreased bleeding and prolonged effect
🗑
|
||||
| Norepinephrine (Levophed) | used in treating shock*
stimulates alpha1 and 2
Mostly Beta 1
🗑
|
||||
| Amphetamine | indirect sympathomimetic
amplifys norepinephrine*
penetreates CNS better than catecholamines
causes euphoria, insomnia, and increased alertness- effects at NE and dopamine synapses
🗑
|
||||
| Beta 1 agonists | dopamine
dobutamine
🗑
|
||||
| Dopamine (Intropin) | treat shock or to increase cardiac output
IV inotropic agents
🗑
|
||||
| Dobutamine (Dobutrex) | treat shock or to increase cardiac output
IV inotropic agents
🗑
|
||||
| Beta 2 Agonists | Albuterol
Salmeterol
Terbutaline
🗑
|
||||
| Albuterol (Proventil) | bronchodilation
inhaled but available oral or parenteral
🗑
|
||||
| Salmeterol (Serevent) | bronchodilation
inhaled but available oral or parenteral
🗑
|
||||
| Terbutaline (Brethine) | prevents premature labor- uterine relaxations
adverse effects of cardiovascular stim
🗑
|
||||
| Beta 1 selective Blockers | Metoprolol
Atenolol
🗑
|
||||
| Metoprolol (Lopressor) | used for cardiac disease, HTN, CHF in pts with underlying asthma or COPD
🗑
|
||||
| Atenolol (Tenormin) | used for cardiac disease, HTN, CHF in pts with underlying asthma or COPD
🗑
|
||||
| Nonselective Blockers | Propranolol
Nadolol
🗑
|
||||
| Propranolol (Inderal) | more lipid soluble, penetrate CNS better than selective agents
adverse: depression
🗑
|
||||
| Nadolol (Corgard) | more lipid soluble, penetrate CNS better than selective agents
adverse: depression
🗑
|
||||
| Alpha and Beta Blockers | Labetalol
Carvedilol
🗑
|
||||
| Labetalol (Normodyne) | useful in CHF
🗑
|
||||
| Carvedilol (Coreg) | useful in CHF
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
Kbailey1
Popular Pharmacology sets