PHAR2002 Term 1 Drugs Adrenoceptors L11
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| Adrenoceptors are what type of receptors? | GPCR
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| Order of Potency: Alpha-adrenoceptors | Adrenaline > Noradrenaline > Isoprenaline (ANI)
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| Order of Potency: Beta1-adrenoceptors | Isoprenaline > Adrenaline > Noradrenaline (IAN)
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| Order of Potency: Beta2-adrenoceptors | Isoprenaline > Noradrenaline > Adrenaline (INA)
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| Most alpha1 are ... Most alpha2 are ... | Postsynaptic, Presynaptic
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| AGONIST Activates alpha and beta (but more strongly for alpha) | Noradrenaline
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| AGONIST Activates alpha and beta (but more strongly for beta) | Adrenaline
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| AGONIST Beta1 and Beta2 Selective | Isoprenaline
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| AGONIST Alpha1 Selective | Phenylephrine
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| AGONIST Alpha2 Selective | Clonidine
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| AGONIST Alpha Selective (but more strongly for alpha2) | alpha-methyl noradrenaline
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| AGONIST Beta Selective (but more strongly for beta2) | Salbutamol
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| ANTAGONIST Alpha Selective | Phentolamine, Phenoxybenzamine
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| ANTAGONIST Alpha Selective (but more strongly for alpha1) | Prazosin
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| ANTAGONIST Beta Selective | Propranolol
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| ANTAGONIST Beta Selective (but more strongly for beta1) | Atenolol
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| Adrenaline at LOW conc. resembles | Isoprenaline
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| Adrenaline at HIGH conc. resembles | Noradrenaline
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| Partial Agonist Alpha2 Selective | Clonidine
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| Partial Agonist Beta Selective | Oxprenolol
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