ANTI INFECTIVE AGENTS Anti Tuberculosis
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| What screening practices should you perform to test tuberculosis? | Screening: PPD, chest x-ray, sputum ( coughing)
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| If positive tuberculosis test what is the treatment? | Therapy 6 months to 2+years; in order to kill bacteria in body
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| What are Isoniazid[INH]? | bactericidal
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| Isoniazid[INH] blocks what? | Blocks vitamin B6 myobacteria rapidly acquire resistance to drug.
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| What is considered as the most useful antiTB drug? | Isoniazid[INH]:
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| What is the most most common adverse reaction for Isoniazid[INH]? | peripheral neuropathy
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| What is the most common side effect for Isoniazid [INH]? | Hepatotoxicity
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| Rifampin causes ___ tract upset and _____? | GI tract upset & rashes.
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| Rifampin Turns body fluid ______color? | orange-red color
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| Rifampin is giving with______? | Isoniazid
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| Rifampin and use of alcohol increases risk of ________? | drug-induced hepatitis
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| Pyrazinamide[PZA]: is ______ & ______________abosrbed orally, and distributed freely to ____ tissues. | rapidly & completely absorbed orally, distributed freely to most tissues.
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| Pyrazinamide[PZA] is effective only against _______ and often causes _____pain | mycobacteria; joint pain
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| Are there any contraindications for Pyrazinamide[PZA] | No
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| Ethambutol is _____ | bacteriostatic
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| Ethambutol is _____ absorbed? | really absorbed;
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| Ethambutol is only effective against ______ | mycobacteria
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| Ethambutol can cause ___ | Optic neuritis
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| Resistance to Streptomycin builds | Resistance develops quickly if used alone.
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| What route do you administer Streptomycin | IM only
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| What are the adverse effects for Steptomycin | Adverse reactions same as other aminogylcisides.;
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| When do you use Steptomycin? | To use on people that are resistant in taking meds
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| Capreomycin, para-aminosalicyclic acid[PAS],cycloserine, kanamycin & ethionamide are _____ drugs. | Secondary drugs
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| Capreomycin, para-aminosalicyclic acid[PAS],cycloserine, kanamycin & ethionamide are ____ effective & ____ toxic than 1st line drugs | Generally less effective & more toxic than 1st line drugs
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| Capreomycin, para-aminosalicyclic acid[PAS],cycloserine, kanamycin & ethionamide are used to treat ______ | severe pulm TB and disseminated infection.
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| Secondary drugs are | Always employed in conjunction with 1st line drug
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| What are the major care implications for | Evaluating treatment
Identifying high risk clients
Administration of 1st line meds
Minimizing adverse effects of 1st line meds
Minimizing adverse interactions of 1st line meds
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Created by:
jwhite223
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