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Pharmacology
ANTI INFECTIVE AGENTS Anti Tuberculosis
| Question | Answer |
|---|---|
| What screening practices should you perform to test tuberculosis? | Screening: PPD, chest x-ray, sputum ( coughing) |
| If positive tuberculosis test what is the treatment? | Therapy 6 months to 2+years; in order to kill bacteria in body |
| What are Isoniazid[INH]? | bactericidal |
| Isoniazid[INH] blocks what? | Blocks vitamin B6 myobacteria rapidly acquire resistance to drug. |
| What is considered as the most useful antiTB drug? | Isoniazid[INH]: |
| What is the most most common adverse reaction for Isoniazid[INH]? | peripheral neuropathy |
| What is the most common side effect for Isoniazid [INH]? | Hepatotoxicity |
| Rifampin causes ___ tract upset and _____? | GI tract upset & rashes. |
| Rifampin Turns body fluid ______color? | orange-red color |
| Rifampin is giving with______? | Isoniazid |
| Rifampin and use of alcohol increases risk of ________? | drug-induced hepatitis |
| Pyrazinamide[PZA]: is ______ & ______________abosrbed orally, and distributed freely to ____ tissues. | rapidly & completely absorbed orally, distributed freely to most tissues. |
| Pyrazinamide[PZA] is effective only against _______ and often causes _____pain | mycobacteria; joint pain |
| Are there any contraindications for Pyrazinamide[PZA] | No |
| Ethambutol is _____ | bacteriostatic |
| Ethambutol is _____ absorbed? | really absorbed; |
| Ethambutol is only effective against ______ | mycobacteria |
| Ethambutol can cause ___ | Optic neuritis |
| Resistance to Streptomycin builds | Resistance develops quickly if used alone. |
| What route do you administer Streptomycin | IM only |
| What are the adverse effects for Steptomycin | Adverse reactions same as other aminogylcisides.; |
| When do you use Steptomycin? | To use on people that are resistant in taking meds |
| Capreomycin, para-aminosalicyclic acid[PAS],cycloserine, kanamycin & ethionamide are _____ drugs. | Secondary drugs |
| Capreomycin, para-aminosalicyclic acid[PAS],cycloserine, kanamycin & ethionamide are ____ effective & ____ toxic than 1st line drugs | Generally less effective & more toxic than 1st line drugs |
| Capreomycin, para-aminosalicyclic acid[PAS],cycloserine, kanamycin & ethionamide are used to treat ______ | severe pulm TB and disseminated infection. |
| Secondary drugs are | Always employed in conjunction with 1st line drug |
| What are the major care implications for | Evaluating treatment Identifying high risk clients Administration of 1st line meds Minimizing adverse effects of 1st line meds Minimizing adverse interactions of 1st line meds |
Created by:
jwhite223
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