Autonomic and Neuromuscular Drugs
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Phenoxybenzamine | Dibenzyline | irreversible a-adrenoreceptor antagonist | vasodilator
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| Propranolol | Inderal | nonselective b-adrenoceptor antagonist | sympatholytic, antihypertensive
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| Phentolamine | Regitine | nonselective a-adrenoceptor antagonist | vasodilator
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| Atenolol | Tenormin | selective b1-adrenoreceptor antagonist | sympatholytic, antihypertensive
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| Terazosin | Hytrin | selective a1-adrenoceptor antagonist | antihypertensive agent, urologic agent
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| Dobutamine | Dobutrex | selective b1-adrenoceptor agonist | sympathomimetic, cardiac stimulant
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| Epinephrine | Adrenalin | nonselective adrenoceptor agonist | sympathomimetic, bronchodilator, vasopressor
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| Tamsulosin | Flomax | uroselective a1-adrenoceptor antagonist | urologic agent
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| Edrophonium | Tensilon | cholinesterase inhibitor | diagnostic agent (for myasthenia gravis - should increase muscle weakness)
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| Pyridostigmine | Mestinon | cholinesterase inhibitor, cholinergic agonist | antimyasthenic agent
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| Pralidoxime | Protopam | cholinesterase reactivator (takes OP off of AChE) | organophosphate antidote
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| Pilocarpine | Salagen | muscarinic ACh receptor agonist | antiglaucoma agent, sialagogue
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| Atropine | Atro-Pen | muscarinic ACh receptor antagonist | anticholinergic agent
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| Solifenacin | VESIcare | muscarinic receptor antagonist | overactive bladder agent
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| Sildenafil | Viagra | phosphodiesterase inhibitor | vasodilator
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| Rocuronium | Zemuron | nondepolarizing NM blocking agent of intermediate duration of action (30-60 min) | paralytic agent
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| Succinylcholine | Anectine | depolarizing NM blocker with short duration of action (5-10 min) | paralytic agent
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| a1 receptors | -vasoconstriction -smooth muscle contraction -iris -GI and urinary spincters -arrector pili | NE > E |
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| a2 receptors | -negative feedback for a1 receptors | E >= NE |
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| b1 receptors | -on the heart -incr HR -incr contractility =incr CO | E = NE |
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| b2 receptors | -smooth muscle relaxation -BRONCHIAL TREE -GI tract -urinary bladder -arteries by skeletal muscle -some coronary arteries | E >> NE |
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| muscarinic receptors | -smooth muscle contraction -gland secretion -lower HR back to normal | ACh |
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| nicotinic receptors | -skeletal muscle contraction | ACh |
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| Phenylephrine | Neo-synephrine | selective a1-adrenoceptor agonist | vasoconstrictor, decongestant
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| Pseudoephedrine | Sudafed | indirect- and direct-acting adrenoceptor agonist | decongestant
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Created by:
jcechter
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