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Goljan 01

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
Dz associated w/ anti-acetylcholine receptor?   show
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show CREST Sx 60% and PSS 10%  
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show Celiac Dz (95%)  
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Dz assoc. w/ anti-glomerular basement membrane?   show
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show Collagen Type IV  
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show Type I DM  
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What Dz is assoc. w/ anti-microsomal Abs?   show
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show primary biliary cirrhosis (90-100%)  
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show Wegner's Granulnomatosis  
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show Polyarteritis Nodosa (PAN) and Hep B associated to PAN  
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Dz. assoc. w/ anti-parietal cell Abs?   show
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show Pernicous Anemia Type I (Ab to B12 prevent binding to IF) Type II (Ab to IF or complex)  
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Dz. assoc. w/ anti-smooth muscle Abs?   show
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show Hashimoto (85%) Grave's (30%)  
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What Dz is associated w/ myasthemia gravis?   show
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show A3  
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show B8  
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show B8 and DR3  
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HLA relationship of Ankylosing Spondylitis?   show
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HLA relationship of Multiple Sclerosis?   show
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HLA relationship of Type I DM?   show
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show DR4  
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What is the MCC of Autoimmune Hemolytic Anemia?   show
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show Drug Induced Hemolytic Anemia  
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What two drugs used for HT for pregnancy?   show
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show Drug Induced Lupus  
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show Procainamide  
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show IgG G is for Gravida  
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What Ab is made against Quinide?   show
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show Macrophages to become active  
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What does IgM activate?   show
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What disease causes leukemoid reaction?   show
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Mononucleosis caused by ------>   show
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What cell does EBV infect?   show
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What is the marker (receptor) for EBV, B-cells?   show
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What drug induces atypical lymphocytes?   show
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MOA of Phenytoin?   show
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What drug causes macrocytic anemia and atypycal lymph?   show
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show Salivary Glands Kissing Disease  
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What test is diagnostic for Mononucleosis?   show
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show Strongyloides Malaria Type I Yes whipworm  
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show polycytemia vera  
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Age of ALL?   show
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show 15-40 40-60  
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show >60  
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Age of CML?   show
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show CLL  
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Characteristic of CLL?   show
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MC Leukemia >60yo?   show
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show lymph nodes  
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49 y.o. 150,000 WBC 1% myeloblasts (<30% blasts) generalized lymphadenopathy   show
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Translocation of CML?   show
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49 y.o. 150,000 WBC 1% myeloblasts (<30%) generalized lymphadenopathy   show
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What gene/chromosome is important in CML?   show
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What translocation is seen in CML?   show
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show bcr-abl gene  
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show Philadelphia Chromosome (+) and LAP (low level) LAP = leukocyte alkaline phosphatase not absorbed by malignant cells  
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show Agnogenic Myeloid Metaplasia  
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Pt. 4yo, w/ generalized non-tender lymphadenopathy, sternal tenderness, hepatosplenomegaly, fever, normocytic anemia, 50,000 WBCs abnormal appearing cells   show
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show CALLA  
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What does CALLA detect?   show
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show CLL age gives it away  
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show AML  
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What leukemia has lots of auer rods?   show
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show 1. polycythemia vera 2. chronic myelogenous leukemia 3. adenogenic myeloid metaplasia 4. essential thrombocytemia myelodysplastic Sx  
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What are the four H's of polycythemia vera?   show
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show Polycythemia ruba vera  
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What is the translocation of Burkitt's Lymphoma?   show
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show EBV  
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What do you see in the pathology slides for Burkitt's?   show
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show Kid 8yo 8 is for translocation 8;14 blacK C-Myc  
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show Macrophages  
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show Abdomen (Peyer's Patches, Paraortic Lymph nodes), Testicle also  
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African Burkitt's lymphoma MC location?   show
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show Cartilage and Elastic Vessels  
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show Neoplastic epidermis cells Helper T-Cells Mycosis Fungoides  
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What is a helper T-cell malignancy that involves skin?   show
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What cell is involved in Mycosis Fungoides?   show
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show Helper T-cell seen in plasma of pat. w/ Mycosis Fungoides  
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show Mucin Producer  
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show diffusely inflitrative (thickened appearance) mucosa and muscularis produced rigid thick, leather-bottle gastric wall  
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