Medications used during labor and delivery
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Betamethasone (corticosteroid) | Preterm labor to enhance fetal lung maturity and surfactant production/maternal and neonate hyperglycemia, pulmonary edema, and heart rate changes in the neonate
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Oxytocin (Pitocin) | To induce labor at term or augment uterine contractions in the first and second stages/placental abruption, impaired uterine blood flow, rapid labor leading to maternal and fetal trauma, uterine rupture, water intoxication.
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Naloxone (Narcan) | Reverses narcotic related respiratory depression in mother and neonate.
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Nifedipine (Procardia) | Tocolytic usedfor treatment of preterm labor. Less side effects when given oral or sublingually/common side effects hypotension,tachycardia, facial flushing, headache. Should NOT be used with Mag Sulfate due to serious effects of low calcium levels.
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Indocin (indomethacin), Clinoril (sulindac), Celebrex (celecoxib) | Prostaglandin Inhibitors used to suppress uterine contractions. Potential fetal side effects:constriction of ductus arteriosus, NEC, intravascular hemorrhage. Should NOT be administered after 32 weeks gestation!
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Magnesium Sulfate (tocolytic,anticonvulsant) | For treatment of preterm labor and preeclampsia/sweating, flushing, nasal congestion, nausea & vomiting, visual blurring, headache and slurred speech.
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