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RNC-OB complications with pregnancy

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Answer
Preterm Labor   ctx resulting in cervical change. Can be caused by infection, stress, hemorrhage/abruption, mechanical stretch of uterus. screened by cervical length or FFN. Managed by bedrest, pelvic rest, tocolytics, hydration, progesterone.  
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FFN   glycoprotein produced by fetal membranes present on if disrution of membrane-uterine junction. Indicates high risk of labor in next 7 days. Contraindicated if sex or SVE in last 24 hours, >3cm dilated, ROM, cerlage, or vaginal bleeding  
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Placenta Accreta   Placenta attached deep into uterine wall, but not into muscle. Most commone type of abnormal implantation. Risk factors: previous c/s or myomectomy, >35 years old, smoker.  
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Placenta Increta   placenta penetrates into uterine muscle (myometrium)  
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Placenta Percreta   placenta penetrates through uterine muscle (myometrium and serosa) and possibly to other organs.  
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Placenta Previa   placenta completely covering (complete), partially covering (partial), or lying at the edge of (marginal) the cervix. Associated with previous uterine surgery, multiple gestation, multip, or >35 years old. Deliver via low segment vertical c/s  
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Placenta Abrution   Premature seperation of placenta.S/S: uterine tenderness, sharp abdominal pain, 'port wine' stained fluid, "board like" abdomen, uterine irritability, frequent ctx, tachycardia, nonreassureing FHTs. Associated with cocaine use, smoking, CHTN, and pre-e  
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(Poly) Hydramnios   >/= 2L, AFI >20 assocaited with cepahlic abnormalities, cleft palate, esophageal atresia, Down's syndrome, hydrops fetalis, maternal diabetes, multiple gestation, abnoramlly large, glistening, tight abdomen. Treated with meds, amnioreduction, or deliver  
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Oligohydramnios   <500cc, AFI<5. Assocaited with chromosomal & congenital abnormalities, >42 wk gest, ROM, IUGR, defects of fetal urinary tract. Risks: cord compression, birth defects, miscarriage, still birth, MSF, PTL. Treatment: amnioinfusion, bedrest, rehydration  
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Anaphylactoid Syndrome (Amniotic Fluid Embolism)   Entrance of amniotic fluid & debris into maternal circulation. Triggers vasoscpasms and vasoconstriction, pulm HTN and hypoxia, heart failure with acute resp. distress. Initiation of clotting cascade leads to hemorrhage and DIC.  
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Prolapsed Cord   Umbilical cord lies beside or below presenting part. Associated with malpresentation, non engagement, AROM, Amnioinfusion, External version, and internal monitors. Risk factors: low lying placenta, preterm, multiple gestation, polyhydramnios.  
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Vasa Previa   Fetal vessels run, unsupported by tissue or cord, in membranes through lower uterine segment below presenting part. Painless vaginal bleeding at ROM. Risk factors: IVF, placental malformation. Requires c/s delivery. APT test determines source of blood.  
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Shoulder Dystocia   H-Help E-evaluate for episiotomy L-legs into McRoberts - thighs on abdomen P-pressure suprapubic E-enter maneuvers R-remove posterior arm R-roll to all fours (Gaskin's maneuver) last resort = cephalic replacement, sympiotomy, or deliberate fracture  
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Hemorrhage   >1000cc vaginally; >1500cc C/S Tone - assess fundus r/o uterine atony Tissue - r/o retained placenta Trauma - r/o cervical or vaginal laceration or hematomas Thrombin - check labs  
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Mo/Mo Twins   least common, highest risk one placenta, one sac risks: cord entanglement, compression  
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Mo/Di Twins   one placenta, two sacs at risk for TTTs  
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Twin to Twin Transfusion Syndrome (TTTs)   blood and nutrients from one twin to the other. Donor = small, anemic, oligo Recipient = large, polycythemic, poly, plethora  
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Di/Di Twins   most common, lowest risk 2 placentas, 2 sacs  
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Gestational HTN (PIH)   HTN first diagnosed during pregnancy after 20 wks that does not progress to preeclampsia and resolves by 12 wks postpartum. Retrospective diagnosis: close observation and overdiagnosis of preeclampsia preferrable. Not associated with poor birth outcomes.  
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Mild Preeclampsia   Pregnancy specific syndrome of decreased organ perfusion defined as HTN >140/90 x2, 4hrs apart + proteinuria >300 mg or 1+. Associated with young age, primip, new paternity, african american, CHTN, multiple gestation.  
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Severe Preeclampsia   Diagnosis of preeclampsia + one of the following: BP >160/110, proteinuria >5g or 3+, creatinine >1.2, platelets <100,000, elevated liver enzymes, persistent symptoms, oliguria, pulmonary edema, seizures  
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Eclampsia   1-2 min seizures with alternating muscle ctx of hands and facial muscles, intermittent respirations, & coma in women diagnosed with preeclampsia. protect airway, prevent aspiration, supplemental O2, minimize risk of recurrent seizure, expedite delivery!  
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Superimposed preeclampsia   new onset of proteinuria or sudden increase in BP in previously well controlled HTN. prognosis worse for mom and baby. Increased risk for placental abruption and IUGR than with preeclampsia or CHTN alone.  
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HELLP   microvascular endothelial damage leads to intravascular platelet activation. Often presen tiwth nonspecific symptomes. Associated with spontaneous hemorrhage, DIC, abruption, renal failure, pulmonary edema, hepatic rupture, severe IUGR  
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Ketoacidosis (DKA)   more common with Type I IDDM insuline definciency, hyperglycemia, ketosis, acidosis, dehydration caused by polyuria, N/V Treated by correction of fluid & electrolyte imbalance, IV hydration, insulin, correct acidosis  
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Gestational Diabetes   Develops second trimester due to increased hormones causing increased resistance to insulin action. Increased risk of Type II IDDM Risk for macrosomia and metabolic consequences Treated with nutritional therapy, exercise, insulin, or glyburide.  
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Type I/II IDDM   Insulin requirements increase in 2nd-3rd trimesters. Increased risk of maternal HTN and preeclampsia, IUGR, and placenta abruption. Risks to infant depend on glucose control throughout pregnancy. insuline requirements decrease rapidly after delivery.  
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Appendicitis   Most common, acute, abdominal condition requiring surgery during pregnancy. S/S: anorexia, N/V, RLQ pain risk of perforation increases with gestation leading to increased risk of PTL  
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Systemic Lupus Erythematosus (SLE)   Autoimmune disorder characterized by photosensitive rash, inflammation of lungs, heart and abdominal organs, raynauds, glomerulonephritis, hematologic abnormalities. Increased risk of flares in pregnancy. Fetus at risk for congenital heart block  
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Hyperthyroid Dysfunction   Typically caused by Graves Disease. Immune system makes antibodies that mimic TSH. Can go into remission 2nd-3rd trimesters due to immune system depression. Can cause CHF, preeclampsia, thyroid storm, miscarriage, PTL, low birth weight  
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Hypothyroid Dysfunction   Typically caused by Hashimoto's disease. Immune system attacks thyroid. decreased levels of thyroid hormone in 1st trimester can effect growth and brain development. Can lead to preeclampsia, anemia, miscarriage, low birth weight, and stillbirth  
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DIC   Inflammatory response releases clotting cascade leading to microclots forming in capillaries decresing clotting factors and causing excessive bleeding. Treat with replacement of pRBCs, FFP, Cryoprecipitate, and platelets.  
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Hemolytic Disease (of Newborn)   Rh+ infant RBC's attacked by antibodies from Rh- mom that form against fetal-D antigen (anti-D) that cross placenta. Sensitization occurs with first pregnancy, miscarriage, or prenatal bleeding. Treat with Rhogam at 28 weeks and after delivery  
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Immune Thrombocytopenic Purpera (ITP)   Antiplatelet antibodies (IgG) coat platelets which are destroyed by spleen. Antibodies cross placenta and can cause bleeding disorders in newborn. Treat with steroids, IV immune Globulins, splenectomy, Rhogam, platelet transfusion.  
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Iron Deficiency Anemia   Most common. decreased Iron = decreased HGB (can't carry enough O2). Treat with 300-325mg Iron supplement daily  
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Folate Deficiency Anemia   decreased folic acid = decreased RBCs. can lead to other types of birth defects  
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Vitamin B12 Deficiency   decreased Vit. B12 = decreased RBCs. can lead to birth defects  
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Anemia   mild physiologic anemia normal due to increased blood volume. S/S tired & weak. Risks: PTL, low birthweight, pp depression, increased risk of defects, blood transfusions. Risk factors: multiple gestation, close pregnancies, heavy periods, teen pregnancy  
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Cocaine Use with Pregnancy   associated with: SAB, PROM, PTL, IUGR, Abruption, congenital anomalies, transient increased CNS and autonomic systems, LBW, and decreased length & head circumference  
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Domestic Violence and Pregnancy   Increased risk for violence &/or frequency effects: IUFD, abruption, fractures, rupture, hemorrhage, inadequate PNC, poor weight gain, anxiety, LBW, miscarriage, exacerbation of chronic illness  
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