Pharm3test3
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| Zidovudine | Nucleoside Reverse Transcriptase
Can be used in pregnancy-given to mom then kid for 3 weeks
Not compatible with stavudine
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| Didanosine | Nucleoside Reverse Transcriptase
Peripheral Neuropathy, pancreatitis
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| Lamivudine | Nucleoside Reverse Transcriptase
Treats Hepatitis B
=Hep B flare when withdrawn
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| Abacavir | Nucleoside Reverse Transcriptase
Sever hypersensitivity reactions
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| Emtricitabine | Nucleoside Reverse Transcriptase
Lamivudine Analog
Treats Hepatitis B
Cause Hyperpigmentation of Palms/Soles
Best tolerated
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| Tenofovir | Nucleotide Reverse Transcriptase
phosphorylated to nucleoside
Treats Hep B
No p450 action
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| Nevirapine | Non-Nucleoside Reverse Transcriptase
Can Cause Rash
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| Evfavirenz | Non-Nucleoside Reverse Transcriptase
P450 Metabolism
Neural tube defects
Long half life
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| Ritonavir | Protease Inhibitors
P450
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| Indinavir | Protease Inhibitors
P450
Nephrolithiasis, skin issues
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| Nelfinavir | Protease Inhibitors
P450
most common used
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| Atazanavir | Protease Inhibitors
P450
abnormal fat distribution
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| Albendazole | Antihelminthic
Inhibits Microtubule Glucose Transport
1st line all the time
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| Pyrantel | Antihelminthic
Activates cholinergics, depolarizing neuromuscular blockade.
OTC
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| Praziquantel | Antihelminthic-Cestodes
Causes Spastic contraction then paralysis due to calcium influx
disloges jaw in cestodes.
Give Mg 15-30g 2 hrs post treatment
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| Metronidazole | Antiprotozoal
Symptomatic, Not for use as a contact or luminal Amebicide
Inhibits DNA synthesis
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| Iodoquinol | Antiprotozoal
Not absorbed, used for luminal
Combined with metronidazole
Unknown MOA
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| Paromomycin | Antiprotozoal
Aminoglycoside, inhibits protein synthesis binds 30s ribosome
Cryptosporidiosis treatment in AIDS patients
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| Niazoxanide | Antiprotozoal
Hydrolyzed to active metabolite.
Interferes with anaerobic respiration
Treats diarrhea from cryptosporidium parvum and Giardia lamblia
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| Chloroquine | Antimalarial
Interferes with feeding mechanism
GI upset, retinopathy, allergic reactions.
once/week dose for prophylaxis
high dose, hydroxychloriquine for rheumatoid/lupus
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| Quinine/Quinidine | Antimalarial
treats chloroquine resistant.
interferes with feeding, more toxic not for proph
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| Mefloquine | Antimalarial
treats resistant
Psychotic/Epileptic effects
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| Artemisinin/Artemether | Antimalarial
Primary for resistan falciparum.
Generates free radicals
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| Primaquine | Antimalarial
Treats tissue infections
Used for follow up therapy
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| Pyrimethamine | Antimalarial
Anti folate
Skin Rashes and Bone marrow suppression
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| Proguanil | Antimalarial
Antifolate
treatment and prophylaxis, not in US
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| Pyrimethamine + Sulfadioxone | Antimalarial
PABA blockade and antifolate
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| Atovaquone + proguanil | Antimalarial
Antifolate + inhibition of electron transport
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| Doxycycline | Antimalarial
Phototoxicity, discoloration of teeth in children
Not for children and pregnant women
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| Dexamethasone | given during neurocysticercosis treatment
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