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NCLEX MEDS TO KNOW

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Question
Answer
ACE   -PRIL Tx: HTN and Heart Failure  
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CHOLESTRAMINE (QUESTRAN)   Decreases Cholesterol -take other meds 1 hr before or 4 hours after -take with milk, juice to avoid constipation -take at meal time SE: Decrease Vit C absorption & Constipation  
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ANTIVIRAL   -VIR (in name) Tx: HIV,viral infections, HSV, HEP C, Chicken pox, RSV Ex: Ritonovir (Norvir)  
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BENZOS   -PAM or has AZE or AZO in name Tx: Antianxiety, anitconvulsant, muscle relaxer, hypnotic, sedative Ex: Diazapam, Tegretol (Carpamazine)  
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BETA BLOCKERS   -OLOL Tx: HTN, Dysrythmia, Angia Ex: Atenolol (can cause bronco constriction)  
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CCB   -PINE Tx: HTN, Angina, dysrythmias (like BB) Ex: Anlotapine (Norvasac) Exception: Diltiazam (Cartizine)-has to be given q 4 hrs Varaprimail (Calan)  
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GLUCOCORTICOIDS/CORTICOSTERORIDS   -SONE or contains CORT Take 2nd, Bronchodilators take 1st Alters normal immune response Tx: adrenal insuffency, suppress inflammation, Addisons, Parkinsons, Post x-plant. If taking NPH, increase NPH dose. Can increase BS Ex: Prednisone (taken in AM)  
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H2 ANTAGONISTS   -DINE or TIDINE Decreased secretion of gastric acid Tx: Acid Reflux, GERD, Heart burn, prevent ulcers Adverse Rxn: dizziness, hallucinations, sleepiness Ex: Semetadine (Tagament)  
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NITRATES   -contains NITR Vasodilation Tx: Angina Ex: Nitroglycerin (nitrostat)  
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PPI   -ZOLE -PRAZOLE Suppresses Gastric Acid Secretion (like H2 Antagonists) Tx: Heartburn, Ulcer Dz, GERD, esophageal erosion  
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SULFONAMIDES   -contains SULF Suppresses bacterial growth Tx: Infections Ex: Sulfasazine  
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THIAZIDE DIURETICS   -ZIDE Tx: HTN & Peripheral Edema Ex: HCL thiazide  
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THROMBOLYTIC   -ASE Used to dissolve clots Ex: Altaplase (Actiplase)  
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THYROID HORMONE   -contains THY Tx: replacement therapy, hypothryoidism Ex: Levothryroxine (Synthroid)  
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BRONCHODILATORS   -LINE Tx: disorders that cause bronchoconstiction, Asthma, COPD, Emphazema Ex:Theophyline 10-20 TDL SE: Restlessness & Increased P  
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ABX   -CYLINE, MYCIN, MICIN Take 1 hr before or 2 hrs after meals SE: Photosensitivity, Decreases contraceptive effectiveness Adverse rxn: yellow skin, Hep, Macular rash-STOP MED Ex: Erthromax, vibramycin, tetracycline (cipro) NO albumin, Mg or Ca antacids  
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REVERSE TRANSCRIPTASE or ANTIHYSTAMINE   -INE  
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Mental and Emotional Conditions or N/V   -ZINE Adverse fx: EPS Tx: schizophrenia, N/V (phen and comp)  
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Cardiac Glycosides   -OXIN Tx: CHF and Heart Arythmias  
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ANTICHOLENERGIC   -OPINE EX: Atropine SE: can't see, pee, sit, poo (Activates SNS-flight or fight) NO with GLAUCOMA = Icreases IOP  
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SNS   -Increases BP, HR, RR -Decreases GI, UO (constipation and urinary retention) -dilated pupils (blurry vison) -constricted blood vessels and dry mouth (FLIGHT OR FIGHT)- acts on Increased ACH  
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PNS   -decreased HR -constriced pupils -Relaxed -Increased sex drive -warm, dry skin REST AND DIGEST- acts on Decreased ACH  
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Is DIG K sparing or wasting?   K WASTING  
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Is ADACTONE K sparing or wasting?   K SPARING  
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What can sudden stopping of TEGRETOL cause?   SEIZURES  
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What do you don't want to take with GRAPEFRUIT JUICE?   (Most Benzo, vir meds, depression meds) -BUSPAR -VARAPAMIL -TEGRETOL (CARBAMAZEPINE)  
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CISPLATIN   -CA med -30% can cause OTO TOXICITY -drink 8-10 glasses of water  
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ANALGESIC   -DONE Tx: Pain  
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ANESTHETIC (local)   -CAINE  
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LIDOCAINE HYDROCHLORIDE   Tx: Heart problems (Ventricular arrhythmia's) caused by MI  
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ANTI-ULCER   -DINE  
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DIURETICS   -MIDE -ZIDE  
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ORAL HYPOGLYCEMIC   -IDE  
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STEROID   -SONE  
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NEUROMUSCULAR BLOCKING   -NIUM anesthesia to produce paralysis (inhibits AcH)  
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What age groups are affected by medications the most?   OLD & YOUNG (greater risk of toxicity) - Absorption -Excretion -Distribution -Metabolism  
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Many med are contraindicated in what?   Breastfeeding and Pregnancy  
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What med is not usually administered with other medications?   Antacids (affects the absorption of med)  
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What can RN do in regards to medications?   -GIVE -HOLD (can never stop or dc med, never tell pt to stop abruptly)  
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What kids of meds should not be taken with other prescribed mediations (unless MD approved)?   -OTC -HERBAL  
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METFORMIN   -Oral Hypoglycemic (decreaseds glucose production) -given in combo with repglinidine Adverse Fx: Muscle Pain  
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METOCLOPRAMIDE (Reglan)   -Antiemetic Tx: N/V prevention, Decreases GERD, GI Stimulant DONT Take with: GI disturbance, hemorrhage or perfusion  
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ANTICOAGULANT   -PARIN Tx: PE, MI, DVT  
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ANGIOTENSION RECEPTOR   -SARTIN Vasoconstriction and Aldosterone secretion Tx: Decrease BP  
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BB   -OLOL Tx: Decrease BP, P, CO, Migraines , Glaucoma  
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AMINOGLYCOSIDES   -CIN/MYCIN Kills Bacteria (ABX) OTO and NEPHRO TOXIC Ex: Vancomycin  
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SSRI   Tx: for Depression, anxiety, OCD  
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What does NITRO not relieve?   UNSTABLE ANGINA  
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How should NITRO be taken?   -1 every 5 min for 3 min -if not relieved go to ER DONT give if BP is below 90/60  
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What are the Sx of ATROPINE OD?   Think Alice in Wonderland -HOT -LOC Changes -RED (flushed face) -DRY/THIRSTY  
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What kids of Meds are COLCHINE and ALLOPURINOL   GOUT MEDS  
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VERAPAMIL (Calan)   CCB Tx: HTN, Angina Adverse Fx: Constipation, N, Diarrhea  
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What med is given for ASYTOLE (no heart beat)?   ATROPINE  
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What med is given for CHF?   ACE  
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What med is given for ANAPHYLACTIC SHOCK?   EPINEPHRINE  
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What med is given for STATUS EPILEPTICS?   VALIUM ATAVAIN  
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What med is given for BIPOLAR?   LITHIUM  
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What med is given for VENTRAL and ATRIAL Complications (A-fib, V-fib, act.)?   AMIODARONE  
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CA MEDS   Massive cell destruction following chemo = Inc. uric acid levels SE: allopecia, decreased resistance to body Need to contact MD before getting vaccinations -NO ASA or ETOH Ex: Elspar, Tamoxifen, Megestrol, alduphosphamide, Busuifan, Vincristine, Beomy  
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TDL of LITHIUM   0.8-1.5 Toxicity: lethargy, hand tremors, muscle weakness  
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TDL of DILANTIN (Phenytoin)   10-20 Toxicity: muscle incordination, nastagmus, diplopia Tx: Seizure  
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TDL of DIGOXIN (Lanoxin)   0.5-2.0 Toxicity: GI disturbance, N/V, anorexia, light flashes and halos Tx; CHF (aflutter)  
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SYNTHROID (Levothyroxine Sodium)   Tx: Hypothyroidism/Myexedema May take several weeks to work. Affects PT time Adverse: Chest pain, nervousness, tremors, D, insomnia, heat intolerance Take on EMPTY STOMACH in AM. -w/h if P is above 100  
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TDL of THYOPHYLLINE   10-20 Toxicity: Restless, dizziness, Insomnia, seizure, HA Tx: Asthma/COPD bronchospasms (works by relaxing smooth muscle)  
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Antidote of IRON   DEFEROXAMINE  
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Antidote of ACETAMINOPHEN   N-ACETYLCYSTEINE (MUCOMYST) Liver failure possible for 4 days  
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Antidote of ETOH W/D   LIBRIUM -bad N/V will occur with any ETOH consumption or products (lotions, cough syrup)  
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Antidote of COUMADIN (Warfarin)   VIT K PT 10-12 sec (control)  
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Antidote of HEPARIN/LOVENOX/DALTEPARIN   PROTAMINE SULFATE PTT: 30-45 sec (control)  
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Antidote of DIGOXIN   DIGIBIND -K will make it worse  
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Antidote of MgSO4 (mag sulfate)   CALCIUM GLUTAMATE  
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Antidote to NARCOTIC ADDICTS   METHODONE  
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MAOI Drugs   Think PANAMA PA-Parnate NA-Nardil MA-Marplan Tx: Depression and Bipolar -Increases seratonin, dopamine, NE, Epi -Last resort after SSRI and tricyclic, can have BP problem and DDI DONT use with SINEMET (Parkinson tx)  
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COGENTIN   Tx: Parkinsons and EPS of other drugs Adverse fx: Increased T, confusion and visual hallucinations SE: Constipation, Increased HR, blurry vision, decreased UO NO in GLAUCOMA  
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THEOPHYLLINE   TDL: 10-20 BRONCHODILATOR (give 1st) -Increases the risk of DIG TOX -Decreased effect of LI and DILANTIN, L K & Mg Tx: Ashtma and COPD Give W/FOOD SE: GI upset, Increased HR, HTN, N/V  
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WHICH MED DO YOU GIVE 1ST?   BRONCHODILATORS (before glucocorticoids)  
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INH (Isoniazid)   Tx: TB Risk: Phenotoin TOX if taken w/ DILANTIN, peripheral neuritis, hepatic, Jaundice -take vit B6 to prevent neuritis (monitor LFT's) -BP will Decrease then return  
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PREDNISONE   Tx: BP (similar to DILANTIN) DONT stop abruptly, Decrease dose in elderly SE: weight gain, hyperplasia of gums **Causes K secretion**  
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DILANTIN (Phenytoin)   Tx: Seizures TDL: 10-20 SE: wght gain, hyperplasia of gums, RED URINE Adverse: **RASH-STOP MED** (not abruptly) DONT give with THEOPHYLLINE (decreased effectiveness) or INH (phenytoin tox) **DONT STOP ABRUPTLY **  
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DIGOXIN   Tx: Afib & HF TDL: 0.5-2.0 W/HOLD: Lower P=60, HR=100 (children) & 48hrs before cardioversion -check apical pulse 1 full min & K -flush H20 (sticky) THEOPHYLLINE increases DIG TOX Sx: visual changes, V/D/N, confusion -Given w/ Lasix (K wasting)- gi  
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MUCOMYST (N-Acetylcytine)   ANTIDOTE for TYLENOL (Acetaminophen) -most common poisoning in children -Admin Orally Sx of Toxic Tylenol: Jaundice, penia, Rash, hypoglycemia  
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RIFAMPIN (Ridadin)   Tx: TB, HIV and Menningitis SE: RED URINE/TEARS -BC doesn't work as well when taking this med  
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What SE do ALL PSYCH meds have? What one is DIFFERENT?   All SE: SNS (flight or fight) but decreased BP Except: LITHIUM (acts different)  
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Mg SULFATE   Stops preterm labor-doesnt affect infant heart, BP or T (decreases R) DONT give if DTR are INEFFECTIVE If mother experiences seizure during Mg admin --> GET BABY OUT ANTIDOTE: Ca GLUTAMATE  
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SINEMET (Levodopa and Carbidopa)   Tx: Parkinsons and Sedative SE: RED URINE and drowsiness DONT give with MAOI or Increased PROTEIN meals KAVA KAVA will DECREASE effectiveness  
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BETHAMETHASONE (Celestone)   Surfactant/Steroid Tx: Lung expansion -give 2nd (bronchodilator 1st-open up lungs) Ex: Glucocorticoid inhaler  
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What medication should you NOT give KIDS for pain?   ASPRIN/NSAID -Associated with Reyes Sx (occurs after viral infection) Sx: V, lethargy, irritability (Baby-D & Increased K) -GIVE TYLENOL  
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When should this med be taken: CARAFATE (Sulcrafate)?   BEFORE MEALS Tx: Duodeal Ulcer (1.5-3 hrs p eating, awakens at night, food helps) -mucomyst barrier  
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When should this med be taken: most ABX?   BEFORE MEALS -1 hr before (or 2 hrs after)  
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When should this med be taken: ZOCOR?   BEFORE MEALS -Tx: hyperlipidemia  
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When should this med be taken: VIBRAMYCIN?   WITH MEALS  
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When should this med be taken: NSAIDS?   WITH MEALS  
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When should this med be taken: CORTICOSTEROIDS?   WITH MEALS  
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When should this med be taken: BIPOLAR MEDS?   WITH MEALS  
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When should this med be taken: CHEPHLOSPORINS?   WITH MEALS  
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When should this med be taken: SULFONAMIDES?   WITH MEALS  
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When should this med be taken: **THEOPHYLLINE**?   WITH MEALS Tx: Asthma/COPD  
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When should this med be taken: **TAGAMENT** (Cimetidine)?   WITH MEALS (daily dose) **BEDTIME** (once daily dose) -H2 antagonist Tx: GERD, Heartburn, Ulcers  
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When should this med be taken: APRESOLINE (hydralazine)?   WITH MEALS Tx: HTN or CHF  
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When should this med be taken: ACYCLOVIR?   WITH MEALS Tx: Herpes  
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When should this med be taken: **K SUPPLEMENTS**?   WITH MEALS  
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When should this med be taken: AMPHOJEL/RENOGEL?   WITH MEALS Tx: Acid Indigestion (antacid) Take 1-2 hrs before Tetracycline (will Dec effectiveness of Tetra) Ex of Tetra: Doxycycline and Vibramycin (Bacterial genital infx)  
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When should this med be taken: MEVACOR (Lovastatin)?   WITH MEALS in PM Tx:Coronary Artery Dz, Hyperlipidemia (decreases Cho) Adverse: muscle pain/tenderness/weakness esp. when with malaise or fever Tx: CA (Chemo med)  
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When should this med be taken: DEXAMETHOSONE?   WITH MEALS Tx: Cerebral Edema, SHOCK, adrenal insufficiency, MS Adverse: Adrenal insufficiency (fatigue, muscle weakness, joint pain, fever, anorexia, N, SOB, dizziness, fainting)  
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When should this med be taken: INDOMETHACIN (Indocin)?   WITH MEALS Tx:RA & Gouty Arthritis -NSAID (decrease inflammation, pain & Temp) Adverse: GI bleed, chest pain, SOB, weakness, slurred speech  
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TETRACYCLINES   DOXYCYCLINE/VIRBAMYCIN/TETRACYCLINE HCL Tx: Bacterial genital infections (gonorrhea, syphilis, rectal infx), Anthrax, Acne, H.pylori, roseasa) -Take WITH MEALS -Avoid direct sunlight/UV, wear protective clothing/sunscreen  
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When should this med be taken: TETRACYCLINES?   WITH MEALS -Take 1h BEFORE BEDTIME to prevent esophageal irritation -Avoid direct sunlight/UV, wear protective clothing/sunscreen  
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When should this med be taken: STEROIDS?   AM MED Tx: Anti-Immflammatory  
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When should this med be taken: DIURETICS?   AM MED Tx: Edema caused by Heart/Liver/Renal Liver Failure  
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When should this med be taken: ARICEPT (Donepezil)?   AM MED Tx: Alzheimers -AVOID OTC Sleep or Cold meds (increase anticholinergic fx) -Tell MD before receiving ANETHESIA  
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When should this med be taken: DEXEDRINE?   AM MED Tx: ADHD & Narcolepsy -DONT drink fruit JUICE with oral solution -Decreases SEIZURE threshold, report Seizures  
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When should this med be taken: ANTACIDS?   AFTER MEALS (p meals)  
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When should this med be taken: most ABX?   AFTER MEALS (2 hrs) **or 1 hr BEFORE**  
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When should this med be taken: GROWTH HORMONE?   PM MED  
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When should this med be taken: SUCRAFATE (Carafate)?   PM MED & BEFORE MEALS Tx: Peptic Ulcer  
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What meds cause RED FLUIDS?   -PREDNISONE- BP med -DILANTIN (phenytoin)- BP med -RIFAMPIN (Rifadin)-TB/Menningococal  
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What is the Tx for EPS?   ANTICHOLENERGICS  
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What meds usually CAUSE EPS?   ANTIPSYCHOTIC MEDS -Atypical won't cause Most Common: Haloperidol (Schizophrenia), Thorazine  
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What are EPS symptoms?   -PSEDOPARKINSONS (tremors, postural instability) -AKINESIA (inability to initiate movement) -TARDIVE DYSKINESIA (inv movement of face and jaw) Tx: BB/Benz -AKATHISIA (inability to remain still)  
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What can you NOT take with MAOI?   -SINTEMET (parkinsons) -ETOH -CHEESE  
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What can you NOT take with EGG allergies?   -MMR -FLU vaccine -Neomycin  
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What interferes with Dilantin (Phenytoin)?   Tx: Epilepsy ***LOTS OF DDI*** (INCREASES PHEYTOIN TOX) -INH (TB infxn), Thyophylline (asthma), disulfuram (ETOH tx), Benzos, Fursemide, St. Johns Wart, ABX, heart meds, anticoagulants  
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What can you NOT take with LEVODOPA/CARBIDOPA (Sinamet)?   Tx: Parkinsons -B6 -MAOI (depression) -  
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If you are ALLERGIC to BAKERS YEAST what VACCINE can you NOT get?   HEP B  
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If you have an MI what med can you NOT use?   -tPA (Tx: ischemic stoke-caused by blood clots)  
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If you have GLAUCOMA what drugs can you NOT take?   -VISINE -LEVODOPA -ATROPINE -ANTICHOLLENERGIC ** Increase IOP**  
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What drugs DECREASE EFFECTIVENESS of THEOPHYLINE?   Tx: Asthma -LI -Dilantin (Epilepsy)  
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What INCREASES the risk of DIGOXIN TOX?   -THEOPHYLINE -DECREASED K -DECREASED MG Dig used to tx CHF (slows HR so it doesn't have to work as hard)  
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What med should INH be taken with?   B6 Tx: TB (also prevent)  
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What CRISIS can DEMOROL (Meperdine) NOT be given in?   SICKLE CELL CRISIS (severe pain, trouble breathing, anemia) Tx: Pancreatitis  
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What med can you NOT give if you have PANCREATITIS?   MORPHINE SULFATE -causes spasm **GIVE DEMEROL**  
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What med is GOOD for PANCREATITIS?   DEMORAL **DONT give MORPHINE**  
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What med can you NOT give if you have no DTR?   Mg SULFATE  
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What BEVERAGES can you NOT have if you are taking ANTIPSYCHOTICS?   -CAFFEINE -APPLE JUICE  
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What DZ can you NOT give ISOTONIC solution to?   -HTN -HEART DZ -RENAL DZ  
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What are ISOTONIC Solutions?   -NS (w/blood prod) -LR (burns-more E) -D5W -D5 1/4 NS Goes into the VASCULAR space Makes FV and BP go UP Tx: N/V, sweating, burns, hemm, trauma  
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What are HYPOTONIC Solutions?   Goes into VASCULAR space then CELLS -1/4 DW -1/2 NS -3% NS with 1/2 NS Hydrating, DOESNT cause BP increase like Iso Tx: Heart/Renal Dz, HTN, Inc Na  
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What DZ can you NOT give HYPOTONIC Solution to?   -CELLULAR EDEMA Watch for decreased BP  
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What are HYPERTONIC Solutions?   Volume Expander(particles)= PULLS from CELLS into VASCULAR -D10W -3% NS -5% NS -TPN -ALBUMIN You can add E to Iso/Hypo = Hyper Tx: Dec Na, 3rd spacing (edema, burns, acities) RETURNS volume to VASCULAR space  
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What SOLUTION would you NOT want to give with PULMONARY EDEMA?   HYPERTONIC (would increase fluid in vascular space which is already increased since they have pulmonary edema) -watch for FVE  
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What are the 4 G's?   -GINKO -GINGER -GENSING -GARLIC  
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What can you NOT take or do if you had the 4 G's?   -GO INTO SURG -PLAVIX -ANTIPLATLET  
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What VITAMIN should you NOT take with ALLOPURINOL?   VIT C Tx: Gout  
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What VS should you HOLD NITROGLYCERINE?   BP below 90/60  
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What med should you NOT take if you are going into SURGERY?   -NSAIDS -HEPARIN -COUMADIN -4 G'S (Ginko, Gensing, Garlic, Ginger)  
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When can you NOT get the VARICELLA (chicken pox) Vaccine?   -PREGNANT -STEROIDS -ACTIVE INFECTION -IMMUNOCOMPROMISED -ALLERGY to GELATIN or NEOMYCIN  
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What is DILAUDID used for?   PAIN -usually after surg  
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ASA poisoning SX and TX?   Sx: breathing fast and sweating Tx: Emetic or gastric lavage  
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4 Actions of Glucocorticoids   1. Changes Mood 2.Alter Defense Mechanism (Decreases Immunity) 3. Breakdown of Protein/Fat --> Ketones --> Acid 4. Inhibit Insulin  
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What Increases Calcium and what Decreases Calcium?   Increases= PTH (parathyroid) Decreases = Calcitonin If there is no PTH the pt can have a seizure due to hypocalcemia (too low Calcium)  
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What does AngiOtensiOn II do in the lungs?   In the lungs it is a potent vasoDILATOR (think O --> Open )  
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What is the category for Coffee, Tea, ETOH, cigarettes?   Stimulants - none 24-48 hours before EEG (tests brain activity) -no sleep the night before  
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What are some Adverse Fx of Ambien?   AE: sleepiness during the day -there are no side effect of HA, discolored urine or irregular HR  
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What is drug toxicity a cause of?   Renal Failure (the way drugs leave the system)  
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What is the only thing that can be added to a TPN or PPN line?   Insulin NO: -Xanax (not in PN line bc it needs digestive system) -Phenagran (causes precipitation in formula) -Demoral (not with TPN)  
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Where does a PEG tube go to?   Empties formula directly into the stomach to be digested.  
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Where does PN go to?   Directly into the blood stream and bypasses the digestive system bc it is not working properly.  
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Where is a PICC line inserted?   Into a peripheral vein, but is long enough to empty into the large veins going directly into the heart  
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Where does a Subclavian Line go to?   It empties directly into the large vein of the heart, reeducating rip of damage to smaller veins.  
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Where does a CVC go?   It empties just above the heart muscle to be distributed.  
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What does the control refer to when dealing with medication and bleeding times?   Control: Premedication bleeding time -usually 1.5-2 times the control  
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The therapeutic level in regards to bleeding time:   It is usually slightly prolonged so that clotting will not occur. 1.5-2 times the control (pre-bleeding time)  
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Antidote of OPIODS   Naloxone (Narcan)  
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Normal Saline 0.9%   Increases circulating volume when RBC are adequate -Replaces losses w/o altering consentrations -Helpful in Na replacement ISOTONIC  
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LR   Replaces fluid and pH buffers -NS w/ K, Ca, and lactate buffers -seen with surgery ISOTONIC  
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D5W   Increases total fluid volume, rehydrating and extratory purposes -provides 170-200 cal/1,000cc for energy -becomes hypotonic in the body (uses up dextrose fast then only H2O remains) ISOTONIC then HYPOTONIC  
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1/2 NS 0.45%   Raises total fluid volume -daily matinee but less value for NaCl replacement -Helps est renal fxn -good for diabetic its who don't need extra glucose HYPOTONIC  
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D5 1/2NS   Daily matinee and body fluid nutrition and rehydration -most common post op fluid HYPERTONIC  
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D5 LR   Same as LR + 180 cal/1000cc -watch for FVO HYPERTONIC  
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D5NS   Replaces fluid NaCl and Calories -watch for FVO HYPERTONIC  
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