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Unit IV

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Question
Answer
Provide support, nourishment and protection to neurons?   Glial Cells  
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Are specialized cells that produce the myelin sheath of nerve fibers in the periphery?   Oligodendorcytes  
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Controls ↑ cognitive function, memory retention, voluntary eye movement, voluntary and expressive speech (Broca’s area)?   Frontal Lobe  
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Contains Wernike’s area, which is responsible for receptive speech and for integration of somatic, visual, and auditory data?   Temporal Lobe  
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Composed of the sensory cortex, controlling and interpreting spatial information?   Parietal Lobe  
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Processing sight?   Occipital Lobe  
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Is concerned with emotion, aggression, feeding behavior and sexual response?   The Limbic System  
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Is responsible for regulating arousal and sleep-wake transitions?   Reticular Activating System (RAS)  
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The ventricles and central canal are normally filled with an average of _____ of CSF?   135mL  
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Olfactory Nerve; (anterior ventral cerebrum)?   I CN  
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Otic Nerve (vision; Thalamus)?   II CN  
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Oculomotor (eye movement muscles and levator palpebrae muscle)?   III CN  
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Trochlear (eye movement muscle, superior oblique muscle)?   IV CN  
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Trigeminal Nerve; (nose, upper/lower jaw, mastication)?   V CN  
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Abducens (lateral rectus of eye)?   VI CN  
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Facial (muscles of expression, cheek, taste anterior 2/3 of mouth)?   VII CN  
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Vestibulocochlear (ear, equillibrium)?   VIII CN  
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Glossopharyngeal (pharynx, posterior tongue/taste)?   IX CN  
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Vagus (PSNS heart, lungs, GI)?   X CN  
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Accessory (sternocleidomastoid and trapezius muscles)?   XI CN  
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Hypoglossal (muscles of the tongue)?   XII CN  
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These preganglionic cell bodies are located in spinal segments T1-L2 (Norepinephrine/Acetylcholine)?   SNS  
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These preganglionic cell bodies are located in the brainstem and spinal segments S2-S4 (only acetylcholine)?   PSNS  
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Anterior blood circulation of the brain?   Internal Coratid Arteries  
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Posterior blood circulation of the brain?   Vertebral Arteries  
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Where is CSF located?   Subarachnoid space (Between Arachnoid & Pia)  
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What are the 3 meninges?   Dura, Arachnoid, & Pia mater  
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Longer subarachnoid space used to obtain CSF during lumbar puncture?   3&4 Lumbar space  
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Eyes do not move together?   Disconjugate Gaze  
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Fine, rapid jerking movements of the eyes?   Nystagmus  
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Pupils constrict with near vision?   Accomodation  
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Early sign of central herniation?   Lack of pupillary constriction  
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Ptosis?   Drooping eyelid  
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Is tested by having the pt identify light touch & pinprick in each of the 3 divisions of the face?   Trigeminal Nerve (V)  
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Myoclonus?   Spasms of the muscles  
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Slow, writhing, involuntary movements of extremities?   Athetosis  
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Impairment of muscle tone?   Dystonia  
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These tracts carry volitional impulses from the cortex to the cranial and peripheral nerves, respectively?   Pyramidal Tract  
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Useful in assessing vasospasm associated with subarachnoid hemorrhage, altered IC blood flow?   Transcranial Doppler  
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Measures metabolic activity of brain to assess cell death or damage?   Positron Emission Tomography (PET)  
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Inability to recognize bodily defect or disease (Lesion Right Parietal Cortex)?   Anosognosia  
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Loss or impaired language faculty (Left Cerebral Cortex Lesion)?   Aphasia/Dysphagia  
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Lack of coordination in articulating speech (Cerebellar or Cranial Nerve function)?   Dysarthria  
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Inability to recognize form of object touch; lesions in parietal cortex?   Astereogenosis  
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Absence of muscle tone and contractility, inability to voluntarily empty; happens in early stages of spinal cord injury?   Atonic (autonomous) bladder dysfunction  
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What causes a hypertonic bladder (I.e. Dribbling)?   Lesions in pyramidal tracts (efferent pathways)  
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What would cause tetraplegia(quadraplegia)?   Transection or mass lesion (Cervical Region)  
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States that the 3 components must remain at a relatively constant volume w/in the closed skull structure?   Monro-Kellie Doctrine  
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Normal ICP ranges?   5-15 mmHg  
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How do you calculate cerebral perfusion pressure?   MAP:(2DBP+SBP/3)- ICP  
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What is normal cerebral perfusion pressure?   60-100mmHg  
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Characterized by systolic HTN w/ widening pulse pressure, Bradycardia & altered respirations?   Cushing’s Triad  
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Results from local disruption of the functional or morphologic integrity of cell membranes & occurs most often in gray matter?   Cytotoxic Cerebral Edema  
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A buildup of fluid in the brain & is manifested by ventricular enlargement?   Hydrocephalus  
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The most sensitive and reliable indicator of pt’s neuro status?   Level of Consciousness (LOC)  
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A medical emergency as this is a sign of brainstem compression & impending death?   Cushing’s Triad  
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Flexion of arms, wrist, & fingers w/ adduction in upper extremities; extension, internal rotation & plantar flexion?   Decorticate Posturing  
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All 4 extremities in rigid extension w/ hyperpronation of forearms & plantar flexion of feet (BAD)?   Decerebrate  
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S/S of increased ICP?   Change in: LOC, V/S, Eyes, Motor. HA & Vomiting not preceded by Nausea.  
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Indications for ICP monitoring?   GCS <8 & abnormal CT/MRI  
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What is normal range of Oxygen in the brain tissue (PbtO2)?   20-40 mmHg (LICOX system)  
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A decrease in _____ constricts cerebral vessels, increase cerebrovascular resistance & decreases CBF?   PaCO2  
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An increase in ____ relaxes smooth muscle, dilates cerebral vessels, decrease cerebrovascular resistance and increase CBF?   PaCO2  
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An osmotic diuretic & is given IV?   Mannitol (Osmitrol) 25%  
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Used to Tx vasogenic edema surrounding tumors & abscesses but not recommended in the mngt of head-injured pt’s?   Dexamethasone (Decadron)  
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Alpha-2 agonist, used for cont. IV sedation of intubated & mechanically ventilated pts in the ICU for up to 24hrs?   Dexamedetomidine (Precedex)  
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Usual Tx for DI?   Fluids, Vasopressin (Pitressin), or Desmopressin Acetate (DDAVP)  
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Death from head trauma can occur at these 3 times?   Immediately after, 2hrs after, or 3 weeks after injury.  
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The 3 classic s/s of epidural hematoma?   Unconsciousness at the scene, Lucid interval, Decreased LOC  
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Results from injury to the brain tissue & its blood vessels (usually venus)?   Subdural Hematoma  
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Prone to cerebral atrophy & subsequent development of subdural hematoma due to an increase incidence of falls?   Chronic Alcoholics  
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Increase malignant & invasive; among the most devastating of primary brain tumors?   Maningioma  
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Medications to Tx cerebral edema?   Dexamethasone (Decadron), Prednisone,, Methylprednisolone (Solu-Medrol)  
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A method of delivering a highly concentrated dose of radiation precisely directed at a location w/in the brain?   Seterostatic Radiosurgery  
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A group of chemo drugs used to Tx brain tumors?   Nitrosoureas, (BCNU)(CCNU)  
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The first oral chemo agent found to cross the blood-brain barrier?   Temozolomide(Temodar)  
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The inability to understand what other people are telling you?   Sensory Receptive Dysphasia  
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Develops decreased LOC & a HA w/in 48hrs of head injury?   Acute Subdural Hematoma  
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The only contraindication to elevating the head 30-45 degrees post-sxg?   Sxg to posterior fossa or if Burr hole has been performed (keep flat or 10-15 degrees)  
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Key s/s of meningitis?   Fever, Severe HA, N/V, nucal rigidity, photophobia  
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Used to Tx encephalitis caused by HSV infection?   Acyclovir (Zevirax) & Vidarabine (Vira-A)  
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A response to ischemia; series of metabolic events?   Ischemic Cascade  
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Area around core area of ischemia is a border zone of decreased blood flow (Possibly Viable tissue)?   Penumbra  
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A blood clot or other debris circulating in the blood?   Embolus  
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Results in a narrowing of the lumen, which blocks the passage of the blood through the artery?   Thrombosis  
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Is dominant for language skills in R handed persons & most L handed persons; aware of deficits?   L Hemisphere  
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All communication & receptive function is lost?   Global Aphasia  
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A disturbance in the muscular control of speech?   Dysarthria  
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Tends to be impulsive and move quickly, safety problems, impaired judgement?   R hemisphere  
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Tx of choice for pts w/ A-Fib who have had a TIA?   Warfarin (Coumadin)  
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Given to pts to prevent stroke after TIA; notify dentist of mes being taken; stop 10-14 days before sxg?   Ticlopidine(Ticlid) & Clopidogrel(Plavix)  
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Is as effective as Mannitol in decreasing ICP?   Dextran(HSD)  
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Must be administered w/in 3-4/5 hrs of the onset of clinical signs of ischemic stroke?   tPA  
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Screening test for tPA?   CT head, occult bleeding, coagulation test, head trauma.  
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Can be administered up to 6hrs after the onset of ischemic stroke?   Intraarterial tPA  
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Complications of SAH?   Re-bleeding before Sxg & Vasospasms  
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Drugs used to Tx vasospasms r/t SAH?   Nimodipine(Nimotop) CCB  
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Is a predictor of both short- and long-term outcome of stroke pts   The NIHSS  
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Blindness in the same half of each visual field?   Homonymous Hemianopsia  
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Results in decreased safety awareness & places the pt at increased risk for injury?   Neglect Syndrome  
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Can be prevented w/ artificial tears or gel to keep the eyes moist and an eye shield (at night)?   Corneal Abrasion  
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Have trouble w/ proprioception; often are impulsive, impatient & tend to deny problems r/t strokes?   R sided brain strokes  
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These pts exhibit exaggerated mood swings; anger, frustration, anxious, fearful, depressed?   L sided brain stroke (Right Hemiplegia)  
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Occurs when the pt overestimates personal cognitive or capabilities & energy levels?   Maladjusted Independence  
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Is the usual first-line therapy for trigeminal neuralgia?   Carbamazepine(Tegretal) or Oxcarbazepine(Trileptal)  
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Injection of glycerol through the foramen ovale into the trigeminal cisern?   Glycerol Rhizotomy  
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Predominate trigger causes of trigeminal neuralgia pain?   Touch & tickle (Temp. changes)  
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Methods for Tx Bell's Palsy?   Moist heat, gentle, electrical stimulation, & Rx exercises.  
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Drug therapy for Bell's Palsy?   Acyclovir(Zovirax) & Prednisone  
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The most recognized organism associated with Guilian-Barre Syndrome?   Campylobacter jejuni  
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Usually develop 1-3 weeks after an upper respiratory or GI infection?   Guilian-Barre Syndrome  
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Most serious complication of Guilian-Barre Syndrome?   Respiratory Failure, SIADH  
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Collaborative care for GBS?   Plasmapheresis within first 2 wks & immunoglobulin(Sandoylobulin)  
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Is due to the loss of vasomotor tone caused by injury; hypotension, bradycardia, decreased SNS, venous pooling (T6 or higher)?   Neurogenic Shock  
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Decreased reflexes, decreased sensation and flaccid paralysis below the level of the injury?   Spinal Shock  
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Most unstable of all injuries because the ligamentous structures that stabalize the spine are torn?   The Flexion-Rotation  injury  
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Spinal cord level; sympathetic outflow; Temp control and blood vessels?   (T1-L4)  
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Level of the Phrenic Nerve?   C3-5  
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Will cause Tetraplegia?   C7 or higher  
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Will cause Paraplegia?   T1 and lower  
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Control upper limbs?   C5-T1  
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is a result of damage to one half of the spinal cord?   Brown-Sequard Syndrome  
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May be used to Tx delayed gastric emptying; cord damage above T5 (GI)?   Metoclopramide(Reglan)  
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Should be given with in 8hrs of spinal cord injury, contra with penetrating trauma?   Methylprednisone(MP)  
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Side effects of Methylprednisone(MP)?   Immunosupression, increased GI bleed, Risk for infection  
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Used to maintain a MAP of >90mmHg to increase perfusion of the spinal cord?   Dopamine(Intropin)  
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Lesion above _____: Bradycardia, hypotension, postural hypotension absence of vasomotor tone?   T5 & Higher  
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Spasms may be controlled with these antispasmotic drugs?   Baclofen(Lioresal), Dantrolene)Dantrium), Tizanidine(Zanaflex)  
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These injections may be given to Tx severe spasticity?   Botulism Toxin Injection  
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A massive uncompensated cardiovascular reaction mediated by  SNS; life threatening emergency?   Autonomic Dysreflexia  
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Nursing interventions for autonomic dysreflexia?   HOB 45, notify MD, Assess cause (bladder or bowel)  
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Arteriolar vasodilator used to Tx autonomic dysreflexia?   Nifedipine(Procardia); decreased BP  
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S/S of autonomic Dysreflexia?   Sudden Acute HA, increased BP, decreased HR, Facial Flushing diaphoresis.  
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Lack of coordination between detrusor contraction and urethral relaxation?   Dyssynergia  
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Have become the first line therapy for acute migraine attack?   Triptans(Sumatriptan[Imitrex])  
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These drugs cause constriction of coronary arteries?   Triptans  
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Excess dose of Triptans may produce these s/s?   Tremors and decreased RR  
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This antiseizure drug has been shown to prevent migraine HA?   Topiramate(Topamax), and Divalproex(Depakote)  
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A type of nonfluent aphasia; damage to the frontal lobe; understands speech?   Broca's Aphasia  
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A type of fluent aphasia; damage to temporal lobe; difficulty understanding others?   Wernicke's Aphasia  
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Medication used to Tx hiccups & shivering?#   Chlorpromazine(Thorazine); antipsychotic.  
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What are the phases of progression of a seizure?   Prodromal, Aural, Ictal, and Postictal phase.  
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Stiffening of the body?   Tonic Phase  
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Jerking of the extremities?   Clonic Phase  
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Is a brief staring spell that lasts only a few seconds, so it often occurs unnoticed?   Absence Seizure (Petit-Mal)  
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Anticipated medications for seizures?   Phenytoin(Dilantin), Ativan, Valium or Versed.  
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Seizure drugs?   Tegretol, & Phenobarbital  
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Used as an adjunct to medications when Sxg is not feasible?   Vagal Nerve Stimulation  
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Trauma changes the Fxn of the axon, resulting in swelling & disconnection. Clinical s/s ↓LOC, ↑ICP, decortication and decerebration & Global aphasia?   Diffuse Axonal Injury (DAI)  
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