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Urinary Disorders

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Question
Answer
UTI Types   Urethra, Cystitis, Prostatitis, Pyelonephritis.  
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Risk Factors of UTI   Vesicoureteral reflux, Obstruction, Calculi, Chronic diseases (DM), Urine characteristics, Gender, Age, Sexual activity, Use of antibiotics, Instrumentation, Genetics, Pregnancy, Hygiene.  
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Cystitis   Inflammation of bladder, Infectious vs. non-infectious, Bacteriuria, Colonization, Seen with elderly, Bacteria /s symptoms.  
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Cystitis Etiology   Pathogen and host, Escherichia coli, Staphylococcus saprophyticus, Klebisiella pneumonia, Proteus and Enterobacter species, Fungal (Candida), Viral and parasitic (trigamonis), Non-infectious (Radiation, Immunologic responses).  
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Cystitis Manifestations   Frequency, Urgency, Hesitancy, Dysuria (pain), Pyuria (foul color/odor), Hematuria (blood), Nocturia, Elderly (Symptoms may be vague, Increased mental confusion, Sudden onset of incontinence, Fever, tachycardia, hypotension, Loss of appetite, nocturia).  
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Pyelonephritis Causes   Defect, Obstruction, Reflux, Pregnancy Spinal cord injuries, Placement of urinary catheter  
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Pyelonephritis Organisms   85% of cases is E.coli, Proteus, or Klebsiella  
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Pyelonephritis Complications   Tissue inflammation=scar tissue (fibrosis), Tubular cell necrosis, Abscess  
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Pyelonephritis Manifestations   Fever, Chills, Flank pain (Tender costal vertebral angle), N/V, diarrhea, Malaise, fatigue, symptoms of cystitis  
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Pyelonephritis Labs   Urinalysis, Midstream urine sample, Culture, Sensitivity, WBC with differential, After treatment follow-up UA 7-14 d  
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Pyelonephritis Other Diagnostics   IVP, Voiding cystourethrogram, Cystoscopy, Manual pelvic or prostate examination  
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Teach Prevention of Pyelonephritis   Drink 2-3 L water/day, avoid sugar-filled drinks, Cleanse perineal area daily, Wipe front to back, Avoid bubble baths, nylon underwear, sprays, douche, Wear loose fitting clothing, Empty bladder regularly  
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Pyelonephritis Antimicrobial Drug Therapy   Sulfonamides: Bactrim, photosensitivity, take ALL. Quinolones: Cipro, Levaquin, must be 18+ effects growth, monitor for dysrhythmias, no milk or antacids. Penicillins: Amoxil or Augmentin, watery diarrhea. Cephalosporins: Duricef, severe diarrhea  
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Pyelonephritis Antiseptic Drug Therapy   Nitrofurantion (Macrodantin), 6-8 glass of water/day, brown urine  
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Pyelonephritis Bladder Analgesic Drug Therapy   Phenazopyridine (Pyridium), orange-red urine  
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Pyelonephritis Antispasmodic Drug Therapy   Hyoscyamine (Anaspaz), Vision changes, dizziness, difficulty passing urine, fast HR  
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Other Therapies for Pyelonephritis   Cranberry juice, avoid caffeine, carbonated beverages, tomato products, increase fluid intake (if possible), Sitz bath, heating pads, I/O, Strict aseptic technique, Maintain closed urinary drainage system, Perineal care  
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Surgical Therapy for Pyelonephritis   Cystoscopy with uretheral stent placement (Monitor I/O, Don’t pull the string!). Ureteroplasty (Repair of ureter, Structure abnormalities, Strictures)  
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Urolithiasis   stones in urinary tract, more common in WHITE MEN, young to middle adulthood  
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Urolithiasis Risk Factors   Personal/family hx, Metabolic disorders, Stasis/Retention, Immobility, Dehydration  
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Urolithiasis Manifestations   Excruciating pain-renal colic, Flank pain, Sudden and unbearable, Nausea, vomiting, Pallor & Diaphoresis, Frequency and dysuria, Oliguria or anuia  
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Urolithiasis Obstruction   Requires prompt recognition and treatment, permanent damage can occur in <48h-weeks; > pressure = < GFR = renal failure  
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Urolithiasis Obstruction Can Lead to   Hydronephrosis (Distention of renal pelvis) or Hydroureter (Distention of ureter, Unrelieved=damage, function, Infection)  
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Urolithiasis Diagnostic Test   UA, (Hemautria, WBC, bacteria, Increase turbidity, Crystals, pH), KUB, CT scan, Renal ultrasonography, Cystoscopy  
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Urolithiasis Interventions   Promote stone passage & hydration, labs, avoid over/under hydration, look at diet, strain all urine  
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Urolithiasis Drug therapy   Morphine, Tordal or Indomethacin (NSAIDs), tamsulosin (Flomax)  
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Urolithiasis Lithotripsy   Extracorporeal shock wave lithotripsy, Moderate sedation, Monitor cardiac rhythm, Monitor for bruising, Hemorrhage, UO, may have Foley catheter, Strain urine  
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Urolithiasis Removal of Stones   Ureteroscopy (Laser beams used, No soft tissue damage), Percutaneous nephrolithotomy (Small incision, stone fragmented by laser/transducer, Nephrostomy tube, Monitor bleeding , pneumothorax, and infection)  
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Urolithiasis Open Surgical Procedures   Ureterlithotomy, Pyelolithotomy, Nephrolitotomy (into kidney)  
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Nephrolitotomy   Large flank and abdominal incision, May place tubes and drains (Penrose, Foley cath), Monitor effects of anesthesia, bleeding, Maintain hydration, prevention of infection, Strain all urine, Teach prevent of future stones  
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Urothelial Cancer   Malignant tumors of urinary tract, 90% occur in bladder, Most common after age of 60, Men more than women, White men more than Black men, Multifocal, Highly invasive, Untreated leads to liver, lung, bone  
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Urothelial Cancer Risk Factors   tobacco use, Occupational (Hair dressing chemicals, Rubber, Paint, Electrical cable, Work in textile industries), Schistosoma heamatobium (Egypt/Sundan) rresh water snail than can invade  
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Urothelial Cancer Manifestations   painless hematuria, Symptoms of UTI, Obstruction  
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Urothelial Cancer Diagnostics   UA-hematuria, Cystoscopy with bladder washings or biopsy, CT scan, MRI  
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Urothelial Cancer Interventions   Removal of tumor for dx and staging; Bacille Calmette-Guerin (BCG), in bladder, Inflammatory reaction to reduce/eliminate tumor; Chemotherapy, in bladder, systemic for metastases; Radiation, Pallitative treatment, Implanted seeds in bladder  
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Urothelial Cancer Surgical Management   Partial or Complete Cystectomy, Invasive tumors; Urinary Diversion will result, Ileal conduit, Cutaneous urostomy, Continent pouch/reservoir (Kock pouch)  
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Bladder Trauma   Penetrating or blunt injury, Stabbing, Gunshot, Fx of pelvis, Sexual assault, Seat belt injur, Requires surgical intervention  
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Urinary Retention   Incomplete emptying of the bladder, Mechanical obstruction or Functional problem, BPH (benign prostetic hyprofetophy)  
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Benign Prostetic Hyprohetophy   Acute inflammation, Scarring /strictures, Bladder calculi, Surgery, Meds: anticholinergics, those with anticholinergic side effects, and antihistamines, Voluntary urinary retention, Constipation  
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Urinary Retention Manifestations   unable to completely empty bladder, Overflow voiding (25-30 ml urine eliminated at frequent intervals), Incontinence, Untreated, can progress to hydronephrosis and acute renal failure  
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Nursing Interventions for Impaired Urinary Elimination   Promote voiding and normal position, Provide privacy, Bathroom rounds, May catheterize to relieve, If male with BPH, use coude, Drain urine in 500ml increments and clamp catheter for 5 minutes to prevent vasovagal response (drop BP, syncopy, pass out)  
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Neurogenic Bladder   Disruption of the nervous system of the bladder that controls bladder filing, perception of fullness, need to void, and emptying, Spastic bladder dysfunction, Flaccid bladder dysfunction  
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Neurogenic Bladder Medications: Cholinergic Drugs   Bethanechol chloride (Urocholine): Stimulates detrusor muscle contraction promoting emptying in flaccid neurogenic bladder, Use in combination with bladder training, Post-op and Postpartum urinary retention, Atropine is antidote, Slow position changes  
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Neurogenic Bladder Medications Anticholingerics/Antispasmodics   Oxybutynin (Ditropan) and Tolterodine (Detrol): Causes bladder muscle relaxation/suppress urge to void, Caution use with glaucoma, SE: Dry mouth, Constipation, Urinary retention, dysrhymias  
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Neurogenic Bladder Treatment   Nutrition; Bladder Training, Measures to stimulate reflex voiding, trigger points, Crede’s method (applying pressure to the suprapubic region with the fingers of one or both hands), Clean intermittent self-catheterization every 3-4 hours  
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Urinary Incontinence   Involuntary loss of urine, NOT a normal of aging  
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Forms of Urinary Incontinence   Stress, Urge, Overflow, Functional, Mixed  
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Stress Incontinence   Increased abdominal pressure; <leakage by Diary, Kegal exercises, Nutritional (avoid things irritating bladder), Vaginal cone therapy(weights), Surgical  
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Stress Incontinence Medications   Duloxetine (Cymbalta), inhibits uptake of norephinephrine and serotonin, Drug of choice for treating Stress UI not relieved by kegals. Side effects: Nausea, Headache, Insomnia, Constipation  
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Urge Incontinence   Behavioral modifications, Surgery is not recommended, Use of collection devices, pads, undergarments  
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Urge Incontinence Drugs   Anticholinergics: Estrogen (Cenestin), Improving vaginal and urethral blood flow, Increased risk of endometrial cancer, Report vaginal bleeding, Increased risk for thrombophlebitis, Avoid smoking  
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Overflow incontinence   Interventions aimed at removal of obstruction: Prostate removal, Repair of genital prolapsed, Intermittent cath, Behavioral, Bethanechol chloride (Urocholine) used after surgery  
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Functional Incontinence   Treat reversible cause. For non reversible: Urinary habit training, Catherization, Pessaries and penile clamps, Containment, Major concern: SKIN BREAKDOWN  
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Total or Mixed Incontinence   Combo of 2 or more types of involuntary urine loss, Use interventions for each type identified  
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Surgical Treatment for Total Incontinence   Look at treating structural causes, Prostatectomy, Cystocele, Urethocele, Artifical sphincter, Augmentation of bladder  
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