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Hematology

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Question
Answer
Fe deficient anemia is most common from __ to __ yrs and also in ____   6mo-2 yrs. Common in 12-20 y.o.  
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Risk factors for Fe deficient anemia   Premature birth (decreased Fe stores), excessive cow's milk in toddlers, malabsorption D/O, poor diet intake, periods of rapid growth, blood loss, infxn, chronic d/o  
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S/sx of Fe deficient anemia   SOB, tachycardia, dizzy/faint c. exertion, pallor, nail bed deformities, fatigue, irritability, myo weakness, impaired healing, loss of skin elasticity, thinning hair, abdm pain, N&V, loss of appetite, low-grade fever, systolic <3 murmur, HF  
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Normal Fe values   2 mo (9-14), 6-12 yrs (11.5-15.5), 12-18 yrs (12-16)  
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RN care for iron deficiency   Supplements for preterm, low birth infants. Encourage breastfeeding in infants <4-6mo. Fe-fortified formula. Restrict milk in toddlers. Diet: high Fe, vit C, protein. Allow frequent rest periods.  
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Milk should not be given to toddlers until   After a meal  
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Fe supplement considerations   Give 1-2h after milk/antacid to prevent decreased absorption. GI effects (constip, diarr, nausea) common initially but decrease later. Give after empty stomach or after meals. Vit C increases absorption. Straw to avoid teeth staining  
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Hgb lvls can take up to __ to increase   3 months  
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PO Fe can take up to __ months to get good Hct levels   6 months. (Will see bump in 6-8 wks)  
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Diet sources of Fe   Cereal, fortified formula. Dried legumes, dried fruits, nuts, green leafy veggies, fortified breads, fortified flour, red meat  
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Thalassemia definition   Genetic D/O causes deficiencies in rate of production of globin chains in hgb causing RBC destruction  
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Thalassemia s/sx   Anemia (pre-Dx): pallor, unexplained fever, poor feeding, enlarged spleen/liver. Progressive (chronic hypoxia, HA, precordial/bone pain, decreased exercise tolerance, listlessness, anorexia). Small stature, delayed sex maturation, bronzed/freckled skin  
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Tx of thalassemia   Early transfusions, chelating therapy  
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Overload of Fe often occurs _____ c. thalassemic pt.   After infection  
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Outcomes for thalessemia   Family support for chronic illness  
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Sickle cell definition   Genetic, abnormal HbS. Increased viscosity, obstructed blood flow, tissue hypoxia d/t sickling  
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Risk factors for sickle cell   Found primarily in African Americans.  
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Sickle cell s/sx   Family Hx, reports of pain/crisis/management, SOB/fatigue, tachycardia, jaundice/pallor, nail bed deform, lethargy, irritability, myo weakness, impaired healing, loss skin elasticity, thinning hair, etc. (same as Fe deficient)  
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Vasoocculsive episodes last typically   4-6 days  
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Acute vasooclusion s/sx   Severe pain (bones/jts/abdm), swollen jts/hands/feet, anorexia, vomiting, fever, hematuria, obstructive jaundice, visual disturbance  
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Chronic vasooclusion s/sx   Increased risk of resp infxn or osteomyelitis, retinal detachment/blindness, systolic murmurs, renal failure/enuresis, liver failure, seizures, skeletal deformities  
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Sequestration of vasooclusion   Excess pool of blood in liver, spleen. Tachycardia, dyspnea, weakness, pallor, shock  
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RN care for sickle cell   Promote rest, admin O2 if hypoxia, FLUIDS, PAIN MANAGEMENT, admin blood products, Tx/prevent infxn  
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RN care after D/C   Emotional support, s/sx infxn/crisis, good hygiene, specific fluid intake requirements, encourage updated immunizations, med ID tags  
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Complications of sickle cell   Enlarged spleen/liver, pain crisis, progressive renal failure, CVA  
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Hemophilia d/t   Genetic deficiency of clotting factors. Easy bruising, uncontrolled bleeding  
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RN care at hospital for hemophilia   Avoid rectal temps, use surg aspetic tech, pressure for 5 min after puncture/inj/needle, control localized bleeding (factor replacement, rest/immobile). RICE for joints in localized bleeding.  
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D/C instructions for hemophilia   Padded crib, safe environ, extra layers clothing, activity restrictions (low contact sports ok like tennis/swim/golf), soft-bristled toothbrush. Regular exercise/PT after bleeding controlled. ID band, support groups  
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Complications of hemophilia   Shock, uncontrolled bleeding (intracranial hemorrhage, airawy obstruction from bleeding in mouth/neck/chest)  
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