Ch 9 Mucus controlling drugs
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| show | Substance that reduces adhesion.
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| show | Rheologic property characteristic of solids; it is represented by the storage modules G'.
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| show | Medication meant to increase the volume or hydration of AW secretions.
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| show | Macromolecular description of pseudoplastic material having both viscosity and elasticity.
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| show | Protein with attached oligosaccharide units.
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| Mucin | show 🗑
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| show | Term connoting any medication or drug that has an effect on mucus secretion; may include mucolytic, expectorant, mucospissic, mucoregulatory, or mucokinetic agents.
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| show | Medication that increases cough ciliary clearance of respiratory secretions.
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| Mucolytic agent | show 🗑
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| show | Drug that reduces the volume of AW mucus secretion and appears to be especially effective in hyper secretory states, such as brochorrhea, diffuse panbron, chiolitis (DPB), CF, and some forms of asthma.
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| show | medication that increases viscosity of secretions and may be effective in therapy of bronchorrhea.
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| show | Secretion, from surface goblet cells and submucosal glands, composed of water, proteins, and glycosylated mucins. The glycoprotein portion of the secretion is termed mucin. Mucus (noun) is the secretion; mucous (adjective) is the cell or gland type.
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| show | Sugar that is the individual carbohydrate unit of glycoproteins.
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| show | Purulent material in the AW. From the greek word from inflammation. When expectorated, phlegm is called sputum.
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| Rheology | show 🗑
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| show | Macromolecular description of the respiratory secretion in true solution, with the physical property of viscosity (usually referred to as the periciliary layer)
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| show | Expetorated Phlegm that contains respiratory tract, oropharyngeal, and nasopharyngeal secretions and bacteria and products of inflammation including polymeric DNA and actin.
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| Viscosity | show 🗑
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| Mucoactive therapy should be considered when? | show 🗑
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| show | Lubricates, waterproofs and protects against osmotic or inflammatory changes.
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| show | Entrap microorganisms, inhibiting chronic bacterial infection and biofilm formation.
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| show | N-acetylcysteine (NAC)
Dornase Alpha
Aqueous aerosols: Water, Saline
Hyperosmolar (7%) saline
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| show | Bronchitis, efficacy not proven for any dose of NAC for an lung disease
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| show | CF
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| Indications for Aqueous aerosols: Water, Saline | show 🗑
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| show | AW clearance (Mucokinetics) for therapy of CF
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| Dosages for N-acetylcysteine (NAC) | show 🗑
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| show | SVN: 2.5mg/2.5mL ampoule, 1 ampoule Q day
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| Dosages for Aqueous aerosols: Water, Saline | show 🗑
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| Dosages for Hyperosmolar (7%) saline | show 🗑
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| show | Mucomyst
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| show | Pulmozyne
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| Brand Names for Aqueous aerosols: Water, Saline | show 🗑
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| show | Hyper-Sal
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| The AW secretion consists of? | show 🗑
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| Drugs that effect Mucociliary clearance? | show 🗑
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| What do Epithelial ion do in the AW? | show 🗑
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| CF AW secretions contain how much Mucin? | show 🗑
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| What does a CF AW consist of? | show 🗑
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| What are the physical properties of mucus? | show 🗑
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| What 3 drugs are approved by aerosol to modify AW secretions? | show 🗑
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| Classic mucolytics | show 🗑
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| What drug does not improve mucus clearance when given as an aerosol and should not be used as a mucoactive agent? | show 🗑
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| What antibiotics is NAC (Mucomyst) incompatible with? | show 🗑
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| show | Expectorants or mucokinetic agents.
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| Other agents that modify AW secretions: | show 🗑
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| show | Reduction in the volume of mucus secretion in patients with CB.
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| show | Staged breathing with small tidal breaths from expiratory reserve volume, repeated until secretions collect in central AWs.
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| show | The PT breathes through a mouth piece that delivers high-flow mini bursts at rates exceeding 200 cycles/min.
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| show | large volume variable frequency are pulse delivery system attached to an inflatable vest worn by PT.
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| Pts with long-term problems of secretion management should? | show 🗑
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