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Antidepressants PTCE

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Question
Answer
Celexa   citalopram   SSRI (interact w/ phenytoin) tab, liq  
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Cymbalta   duloxetine   SSRI (interact w/ phenytoin) cap  
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Lexapro   escitalopram   SSRI (interact w/ phenytoin) tab  
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Prozac   fluoxetine   SSRI (interact w/ phenytoin) cap, liq  
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Luvox   fluvoxamine   SSRI (interact w/ phenytoin) tab  
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Paxil   paroxetine   SSRI (interact w/ phenytoin) tab  
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Zoloft   sertraline   SSRI (interact w/ phenytoin) tab  
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Effexor   venlafaxine   SSRI (interact w/ phenytoin) tab, timed release cap  
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TCAs   MOA: block reuptake of norepinephrine or serotonin CI: depression, nocturia AR: cardiotoxic @ high doses, postural hypotension (elderly), drowsiness, anticholinergic effects   SPECIAL: may not have results for several weeks  
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Elavil   amitriptyline   TCA tab, injection  
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Anafranil   clomipramine   TCA cap  
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Norpramin   desipramine   TCA tab  
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Sinequan, Zonalon   doxepin   TCA cap, liquid, cream  
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Tofranil   imipramine   TCA cap, injection, tab  
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Pamelor, Aventyl   nortriptyline   TCA cap, oral solution  
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Vivactil   protriptyline   TCA tab  
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Tetracyclic Antidepressant   CI: depression and anxiety AR: high potential for seizure SPECIAL: delayed effect, slow discontinuation Ludiomil   maprotiline, tab  
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Monoamine Oxidase Inhibitors   MOA: inhib enzymes that breakdown catecholamines CI: atypical depression AR: possible hypertension   SPECIAL: discontinue for 2 weeks prior to new therapy beginning, avoid certain foods w/ tyramine (aged cheeses, certain wines/yeast products) DO NOT TAKE w/ : ephedrine, amphetamine, metyhlphenidate, levodopa, meperidine  
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Nardil   phenelzine   MAOI tab  
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Eldepryl   selegiline   MAOI tab  
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Parnate   tranylcypromine   MAOI tab  
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SSRIs   MOA: block reuptake of serotonin AR: nervousness, insomnia, nausea, diarrhea, loss of weight, decreased libido, ejac disturb CI: major depression, OC, anxiety   SPECIAL: delay of onset 10-21 days, avoid alch, interact with phenytoin  
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