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Antidepressants PTCE
| Question | Answer | |
|---|---|---|
| Celexa | citalopram | SSRI (interact w/ phenytoin) tab, liq |
| Cymbalta | duloxetine | SSRI (interact w/ phenytoin) cap |
| Lexapro | escitalopram | SSRI (interact w/ phenytoin) tab |
| Prozac | fluoxetine | SSRI (interact w/ phenytoin) cap, liq |
| Luvox | fluvoxamine | SSRI (interact w/ phenytoin) tab |
| Paxil | paroxetine | SSRI (interact w/ phenytoin) tab |
| Zoloft | sertraline | SSRI (interact w/ phenytoin) tab |
| Effexor | venlafaxine | SSRI (interact w/ phenytoin) tab, timed release cap |
| TCAs | MOA: block reuptake of norepinephrine or serotonin CI: depression, nocturia AR: cardiotoxic @ high doses, postural hypotension (elderly), drowsiness, anticholinergic effects | SPECIAL: may not have results for several weeks |
| Elavil | amitriptyline | TCA tab, injection |
| Anafranil | clomipramine | TCA cap |
| Norpramin | desipramine | TCA tab |
| Sinequan, Zonalon | doxepin | TCA cap, liquid, cream |
| Tofranil | imipramine | TCA cap, injection, tab |
| Pamelor, Aventyl | nortriptyline | TCA cap, oral solution |
| Vivactil | protriptyline | TCA tab |
| Tetracyclic Antidepressant | CI: depression and anxiety AR: high potential for seizure SPECIAL: delayed effect, slow discontinuation Ludiomil | maprotiline, tab |
| Monoamine Oxidase Inhibitors | MOA: inhib enzymes that breakdown catecholamines CI: atypical depression AR: possible hypertension | SPECIAL: discontinue for 2 weeks prior to new therapy beginning, avoid certain foods w/ tyramine (aged cheeses, certain wines/yeast products) DO NOT TAKE w/ : ephedrine, amphetamine, metyhlphenidate, levodopa, meperidine |
| Nardil | phenelzine | MAOI tab |
| Eldepryl | selegiline | MAOI tab |
| Parnate | tranylcypromine | MAOI tab |
| SSRIs | MOA: block reuptake of serotonin AR: nervousness, insomnia, nausea, diarrhea, loss of weight, decreased libido, ejac disturb CI: major depression, OC, anxiety | SPECIAL: delay of onset 10-21 days, avoid alch, interact with phenytoin |