Immunology Lecture
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| Which of the following substances is produced by plasma cells (mature B cells)? | immunoglobulins
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| The cell markers present on the surface of all cells that indicate "self" or "non-self" are called | epitopes
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| The classification of immunoglobulin responsible for allergic reactions by stimulating Mast Cells to release histamine is | IgE
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| The primary immune system organ which produces stem cells, many of which will eventually mature into various types of lymphocytes, is(are) the | bone marrow
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| The chemical message substances released from Helper T cells which not only regulate B cell maturation and proliferation, but also differentiation of immature T cells into mature cytotoxic and regulatory T cells are | lymphokines
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| Type IV - Delayed Hypersensitivity |
Contact dermatitis for latex, adhesive, topical medication, or cosmetic sensitivity
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| Type III - Immune Complex Disease |
Acute inflammation and local tissue damage due to the clumping of normally circulating antigen-antibody complexes. Ex: systemic lupus erthematosus
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| Type I - Immediate/Allergic | Typical allergic reactions such as hay fever. May result in anaphylaxis
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| Type II - Cytotoxic Reactions to Self |
The body's own tissue is recognized as foreign and the immune system is activated. Results in slow destruction of cellular membranes of normal tissues. Ex: blood transfusion reactions, myasthenia gravis
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| The most appropriate position to place a person in if he/she is experiencing anaphylatic shock is | supine with feet elevated
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| Passive Natural Immunity | D.
Transplacental, colostrum, and/or breast milk antibody exposure from mother to fetus/baby
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| Passive Artificial Immunity | Inoculation of antibody or antitoxin
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| Active Natural Immunity | Natural contact and infection with an antigen (environmental exposure)
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| Active Artificial Immunity | Inoculation of antigen (vaccination); live or dead antigen
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| antigen | Any foreign substance in the body that does not have the characteristic cell surface markers of that individual and is capable of eliciting an immune response
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| The neuroendrocrine organ essential for regulation of the immune system is the | Pituitary
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| The immune organ where T cells differentiate from their origin of lymphoid stem cells and mature is(are) the | thymus
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| Primary organs of the immune system | bone marrow and thymus
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| secondary organs of the immune system | lymph nodes, spleen, tonsils, adenoids, appendix
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| Tissues of immune system | peyers patches
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| cells of immune system | luekocytes, lymphocytes (NK cells), other phagocytes
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| granulocytes | neutro-, eosino, baso-phils
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| the _____ filters and destroys old RBCs | spleen
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| What is the spleens immune role? | filters blood antigens
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| monocytes produce what | macrophages
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| ______ bring in Ag thru the blood to the spleen | macrophages
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| the spleens ______ destroy antigens | T cells
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| the spleen's ______ produce and antibody vs the antigen | B cells
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| mature B cells differentiate into | plasma cells
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| any substance capable of triggering an immune response is a _______ | antigen
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| epitopes- | anything on the antigen that the antibody identifies and attaches to
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| what happens if an epitope is misinterpreted where self is identified as nonself | auto immune disease
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| proteins present on the surface of all cell bodies | self markers/ MHC
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| what allows the immune system cells to recognize and communicate with one another? | MHC
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| growth and reproduction of stem cells are controlled by proteins called: | growth inducers and differentiation inducers
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| the most numerous of WBCs; die after phagocytosis and contribute to pus formation | neutrophils
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| These cells clean up after neutrophils and kill any damaged but not dead backteria or too large for neturophils | monocytes
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| weak phagocytes that participate in allergic disorders; destroy parasites | eosinophils
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| histamine is produced by what cells | basophils
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| basophils- | similar to mast cells; produce histamine;
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| NK cells are what type | lymphocytes
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