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Med-surge Immunology

Immunology Lecture

Which of the following substances is produced by plasma cells (mature B cells)? immunoglobulins
The cell markers present on the surface of all cells that indicate "self" or "non-self" are called epitopes
The classification of immunoglobulin responsible for allergic reactions by stimulating Mast Cells to release histamine is IgE
The primary immune system organ which produces stem cells, many of which will eventually mature into various types of lymphocytes, is(are) the bone marrow
The chemical message substances released from Helper T cells which not only regulate B cell maturation and proliferation, but also differentiation of immature T cells into mature cytotoxic and regulatory T cells are lymphokines
Type IV - Delayed Hypersensitivity Contact dermatitis for latex, adhesive, topical medication, or cosmetic sensitivity
Type III - Immune Complex Disease Acute inflammation and local tissue damage due to the clumping of normally circulating antigen-antibody complexes. Ex: systemic lupus erthematosus
Type I - Immediate/Allergic Typical allergic reactions such as hay fever. May result in anaphylaxis
Type II - Cytotoxic Reactions to Self The body's own tissue is recognized as foreign and the immune system is activated. Results in slow destruction of cellular membranes of normal tissues. Ex: blood transfusion reactions, myasthenia gravis
The most appropriate position to place a person in if he/she is experiencing anaphylatic shock is supine with feet elevated
Passive Natural Immunity D. Transplacental, colostrum, and/or breast milk antibody exposure from mother to fetus/baby
Passive Artificial Immunity Inoculation of antibody or antitoxin
Active Natural Immunity Natural contact and infection with an antigen (environmental exposure)
Active Artificial Immunity Inoculation of antigen (vaccination); live or dead antigen
antigen Any foreign substance in the body that does not have the characteristic cell surface markers of that individual and is capable of eliciting an immune response
The neuroendrocrine organ essential for regulation of the immune system is the Pituitary
The immune organ where T cells differentiate from their origin of lymphoid stem cells and mature is(are) the thymus
Primary organs of the immune system bone marrow and thymus
secondary organs of the immune system lymph nodes, spleen, tonsils, adenoids, appendix
Tissues of immune system peyers patches
cells of immune system luekocytes, lymphocytes (NK cells), other phagocytes
granulocytes neutro-, eosino, baso-phils
the _____ filters and destroys old RBCs spleen
What is the spleens immune role? filters blood antigens
monocytes produce what macrophages
______ bring in Ag thru the blood to the spleen macrophages
the spleens ______ destroy antigens T cells
the spleen's ______ produce and antibody vs the antigen B cells
mature B cells differentiate into plasma cells
any substance capable of triggering an immune response is a _______ antigen
epitopes- anything on the antigen that the antibody identifies and attaches to
what happens if an epitope is misinterpreted where self is identified as nonself auto immune disease
proteins present on the surface of all cell bodies self markers/ MHC
what allows the immune system cells to recognize and communicate with one another? MHC
growth and reproduction of stem cells are controlled by proteins called: growth inducers and differentiation inducers
the most numerous of WBCs; die after phagocytosis and contribute to pus formation neutrophils
These cells clean up after neutrophils and kill any damaged but not dead backteria or too large for neturophils monocytes
weak phagocytes that participate in allergic disorders; destroy parasites eosinophils
histamine is produced by what cells basophils
basophils- similar to mast cells; produce histamine;
NK cells are what type lymphocytes
Created by: cdphipps21