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PTA Cardio Pharm Matching
Diuretic Agents
Increase secretion of sodium and urine => reduction in plasma volume and BP; thiazide, loop and potassium sparing
Anti-hyperlipidemia Agents
AKA Statins; lipid modifying agents; inhibit anzyme aciton in cholesterol synthesis, break down LDL, decrease triglycerides, and increase HDL
Calcium Channel Blocker Agents
Decrease calcium entry int o calcium smooth mm cells resulting in diminished myocardial contraction, vasodilation, and oxygen demand
Nitrate Agents
Decrease ischemia through smooth mm relaxation and dilation of peripheral vessels
Alpha Adrenergic Antagonist Agents
Reduce perohperal vascular tone by blocking alpha-1-adrenergic receptors; causes dilation and decrease in BP
Thrombolytic Agents
Facilitate clot dissolution through conversion of plasminogen to plasmin; plasmin breaks down clots and opens blood vessels
Positive Inotropic Agents
Increase force and velocity of myocardial contraction; slow the heart rate; decrease conduction velocity through AV node and decrease degree of activation of SNS
ACE Inhibitor Agents
Suppresses enzyme that converts angiotensin 1 into angiotensin 2; decreasing blood pressure and after load
Beta Blocker Agents
Block B-Adrenergic receptors; decrease myocardial oxygen demand by decreasing heart rate and contractility
Anti-thrombotic Agents
inhibit platelet aggregation and clot formation
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