Question | Answer |
What is Azotemia? | Accumulation of nitrogenous waste products (measured by BUN & Creatinine) |
What is Uremia? | Renal function declines and causes systemic symptoms |
What is Oliguria? | <400mL urine in 24 h |
Three types of acute kidney injury | Pre-renal: before blood gets to kidney; hypovolemia, hypotension, no profusion to kidney (i.e., code pt.)
Intrarenal: direct damage to renal tissue by medications (nephrotoxins), renal artery stenosis, CT dye
Post renal: obstr to urine (kidney stone) |
What is Acute Tubular Necrosis? | Tubules in kidney become necrotic, sloth off and block tubes |
What is the initiating phase of acute kidney injury? | time of insult until S&S appear |
When does the oliguric phase of acute kidney injury occur? | 1-7 days onset, can last 2 wks or longer |
What urinary chgs take place in oliguric phase? | Fixed specific gravity (1.010); casts in urine (tubular necrosis, sloughing off) |
What FVE symptoms occur in oliguric phase? | edema, jugular venous distention (JVD), crackles, HTN |
Why does Metabolic Acidosis occur in oliguric phase? | kidneys producing decrease amount of bi carb |
How to treat Na balance and K excess in oliguric phase? | Na may be normal or decreased (may be diluted b/c of fluid retention)
Treat K is >6 or if pt symptomatic |
What hematologic disorders occur in the oliguric phase? | Anemia, altered WBC function--puts at risk for infection |
What neurological disorders in oliguric phase? | fatigued, decreased concentration, can lead to seizures and coma |
What is the diurectic phase? | "getting better" phase; gradual increase in urine output, kidneys can excrete waste, but cannot concentrate urine--putting out 1-3L/day
Watch for hypovolemia, decrease bp, can last 1-3 wks |
What is the recovery phase? | increase GFR, renal function may take up to 12 mos to stablize; kidneys are very finicky...do not recover quickly |
What are diagnostics for Acute Renal Failure? | Depend of precursors--if pre-renal, pt may be dehydrated, push fluids & see if kidneys respond
Intrarenal: UA-look for casts, proteins, WBC, RBC, Na; can do renal biopsy, CT, ultrasound |
What is collaborative care for acute renal failure? | 1)need to manage bp; if kidneys are failing they will be hypertensive, but if cause is pre-renal, they may be hypotensive. If fluids don't work at first, pull back and put on fluid restriction 2)treat hyper K, 3) dialysis |
What are indications for dialysis? | Volume overload: not producing enough urine, need cardiac or pulmonary compromise
Hyper K: meds not working; getting EKG chgs
Bi carb of <15-metab acidosis
BUN >120
Chg in mental status
Cardiac issues, hx cardiac issues to get volume off & cleanse b |