Term | Definition |
Quinapril | Func. Class: Antihypertensive
Chem. Class: Angiotensin-converting enzyme (ACE) inhibitor
Action: reduce blood pressure |
Ramipril | Func. Class: Antihypertensive
Chem. Class: ACE inhibitor
Action: Reduces high blood pressure |
Losartan Potassium | Func. Class: Antihypertensive
Chem. Class: Angiotensin II receptor (type AT1)
Action: receptor blocker for high blood pressure |
Losartan Potassium/Hydrochlorothiazide | Func. Class: Diuretic
Chem. Class: Angiotensin II receptor
Action: Angiotensin II receptor blocker (ARB) + thiazide diuretic. |
Olmesartan Medoxomil | Func. Class: Antihypertensive
Chem. Class: Angiotensin II receptor (type AT1) antagonist
Action: Angiotensin II receptor blocker (ARB) for blood pressure |
Valsartan | Func. Class: Antihypertensive
Chem. Class: Angiotensin II receptor antagonist (type AT1)
Action: Angiotensin II receptor blocker (ARB) for blood pressure |
Valsartan/Hydrochlorothiazide | Func. Class: Antihypertensive
Chem. Class: Class: Angiotensin II receptor antagonist (type AT1) and thiazide diuretic for blood pressure
Action: Angiotensin II receptor blocker (ARB) for blood pressure and diuretic |
Diltiazem Hydrochloride | Func. Class: Calcium channel blocker and antihypertensive drug
Chem. Class: benzothiazepine
Action: Calcium channel blocker used to lower blood pressure |
Verapamil Hydrochloride | Func. Class: Calcium channel blocker and antihypertensive
Chem. Class: Diphenylalkylamine
Action: is to block voltage-dependent calcium channels |
Amlodipine Besylate | Func. Class: Antianginal calcium channel blocker, antihypertensive
Chem. Class: Dihydropyridine
Action: Dihydropyridine calcium channel blocker for high blood pressure |
Amlodipine Besylate/Benazepril | Func. Class: Antianginal calcium channel blocker, antihypertensive
Chem. Class: ACE inhibitor
Action: dihydropyridine calcium channel blocker with ACE inhibitor for high blood pressure |
Nifedipine | Func. Class: Calcium channel blocker, antihypertensive
Chem. Class: Dihydropyridine
Action: Dihydropyridine calcium channel blocker to reduce blood pressure |
Hydralazine Hydrochloride | Func. Class: Antihypertensive, vasodilator
Chem. Class: Phthalazine
Action: Directly relaxes vascular smooth muscle to cause peripheral vasodilation, decreasing arterial BP and peripheral vascular resistance. |
Isosorbide Mononitrate | Func. Class: Antianginal, vasodilator
Chem. Class: Nitrate
Action: a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump. Can help with chest pain |
Nitroglycerin | Func. Class: Coronary vasodilator, anyianginal
Chem. Class: Nitrate
Action: decreses pre/afterload which decreases left ventricular end-diastolic pressure and reduce high blood pressure |
Atorvastatin | Func. Class: Antilipidemic
Chem. Class:HMG-CoA reductase inhibitor
Action: inhibits HMG-CoA reductase enzyme, which reduces cholesterol synthesis leads to plaque regression |
Lovastatin | Func. Class: Antilipemic
Chem. Class: HMG-CoA reductase inhibitor
Action: inhibits HMG-CoA reductase which reduces cholesterol synthesis |
Pravastatin Sodium | Func. Class: Antilipemic
Chem. Class: HMG-CoA reductase inhibitor
Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
Rosuvastatin Calcium | Func. Class: Antilipemic
Chem. Class: HMG-CoA reductase inhibitor
Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
Aspirin | Func. class.: Opiate analgesic
Chem. class.: Semisynthetic derivative
Action: Inhibits ascending pain pathways in CNS, increases pain threshold, alters pain perception
Used: mod-severe pain |
Furosemide | Func. class.: Loop diuretic
Chem. class.: Sulfonamide derivative
ACTION: Ascending loop of Henle in kidney, inhibiting reabsorption of electrolytes; inc. excretion of K+ in the distal tubule of the kidney; responsible for slight antihypertensive effec |
Chlorthalidone | Func. class.:Diuretic
Action: Treats high blood pressure |
Hydrochlorothiazide | Func. class.: Diuretic, antihypertensive
Chem. class.: Thiazide, sulfonamide derivative
ACTION: acts on the distal tubule in the kidney, increasing excretion of sodium, water, chloride, and potassium
USES: Edema, hypertension, diuresis, CHF |
Hydrochlorothiazide; Triamterene | Func. class.: Diuretic, antihypertensive
Chem. class.: Thiazide, sulfonamide derivative
ACTION: acts on the distal tubule in the kidney, increasing excretion of sodium, water, chloride, and potassium
USES: Edema, hypertension, diuresis, CHF |
Spironolactone | Func. class.: Potassium-sparing diuretic
Chem. class.: Aldosterone antagonist
ACTION:Competes w/ aldosterone at receptor sites in distal tubule in the renal system, causing excretion of sodium chloride, water, retention of potassium, phosphate |
Potassium | Func. class.: Electrolyte, mineral replacement
Chem. class.: Potassium
ACTION: used for adequate transmission of nerve impulses & cardiac contraction, renal function, intracellular ion maintenance |
Doxazosin Mesylate | Func. class.: Peripheral α-adrenergic blocker, antihypertensive
Chem. class.: Quinazoline
ACTION: dilates peripheral blood vessels, PBV resistance lowers, reduction in BP results from blocked peripheral α-adrenergic receptors |
Terazosin | Func. class.: Antihypertensive
Chem. class.: α-Adrenergic blocker (peripherally acting)
ACTION: dilates peripheral blood vessels, PBV resistance lowers, reduction in BP results from blocked peripheral α-adrenergic receptors |
Clonidine | Func. class.: Antihypertensive, centrally acting analgesic
Chem. class.: α-adrenergic agonist
Action: Inhibits sympathetic vasomotor center in CNS, reduces impulses in Sympathetic NS; BP, pulse rate, cardiac output decreased |
Propranolol Hydrochloride | Func. class.: Antihypertensive, antianginal, antidysrhythmic (class III)
Chem. class.: β-Adrenergic blocker
ACTION:Nonselective β-blocker with negative inotropic, chronotropic, dromotropic properties |
Propranolol Hydrochloride/Hydrochlorothiazide | Func. class.: AHTN, antianginal, antidysrhythmic
ACTION:Nonselective β-blocker w/ negative inotropic, chronotropic, dromotropic properties
Func class: Diuretic, AHTN
ACTION: acts on the distal tubule in the kidney, inc. excretion of Na+, h2o, Cl, and K |
Atenolol | Func. class.: Antihypertensive
Chem. class.: β-Blocker; β1-, β2-blocker (high doses)
slows conduction of AV node, dec. HR, dec. O2 consumption in myocardium; dec. renin-aldosterone-angiotensin system at high doses, |
Atenolol; Chlorthalidone | Antihypertensive
Action decreases heart rate and blood pressure
Func. class.:Diuretic
Action: Treats high blood pressure |
Simvastatin | Func. Class: Antilipemic
ChemClass: HMG-CoA reductase inhibitor
Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
Fenofibrate | Func. Class: Antilipemic
Chem. Class: Fibric acid derivative
Action: lowers triglyceride and cholesterol levels |
Gemfibrozil | Func. Class: Antilipemic
Chem. Class: fibric acid derivative
Action: lowers triglyceride and cholesterol levels |
Ezetimibe | Func. Class: Antilipemic
Action: decreases cholesterol/triglyceride levels |
Ezetimibe; Simvastatin | Func. Class: Antilipemic
Chem. Class: HMG-CoA reductase inhibitor
Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
Warfarin | Func. Class: Anticoagulant
Action: prevention of clotting |
Dabigatran Etexilate Mesylate | Func. Class: Anticoagulant
Chem. Class: Thrombin inhibitor
Action: Decreased thrombus formation/extension |
Rivaroxaban | Func. Class: Anticoagulant
Chem. Class: Factor Xa inhibitor
Action: oral or novel anticoagulant that prevents DVT, stroke and systemic embolism |
Clopidogrel Bisulfate | Func. Class: Platelet aggregation inhibitor
Chem. Class: Thienopyridine derivative
Action: decreases possibility of stroke, MI by decreasing platelet aggregation |
Digoxin | Func. Class: Inotropic antidysrhythmic cardiac glycoside
Chem. Class: Digitalis preparation
Action: inhibits Na--K+ ATPase which increase calcium for contractile proteins=increases cardiac output/decreased edema/pulse |
Amiodarone Hydrochloride | Func. Class: Antidysrhythmic (Class III)
Chem. Class: Iodinated benzofuran
Action: decreased amount/severity of ventricular dysrhythamias |
Metoprolol | Func. class.: Antihypertensive, antianginal
Action: Lowers B/P; reduces elevated renin plasma levels; blocks β2-adrenergic receptors in bronchial |
Carvedilol | Func. class.: Antihypertensive
Action: decreases cardiac output, exercise-induced tachycardia, reflex orthostatic tachycardia; causes reduction in peripheral vascular resistance & vasodilatation |
Nebivolol Hydrochloride | Func. class.: Antihypertensive
slows conduction of AV node = decreased HR, decreases O2 consumption, decreases renin-aldosterone-angiotensin system at high doses |
Benazepril Hydrochloride | Func. class.: Antihypertensive
Suppresses renin-angiotensin-aldosterone system; inhibits ACE, preventing conversion of angiotensin I to angiotensin II |
Enalapril Maleate | Func. class.: Antihypertensive
(used to treat high blood pressure and heart failure)
inhibits ACE; prevents conversion of angiotensin I to angiotensin II, resulting in dilatation of arterial and venous vessels |
Lisinopril | Func. class.: Antihypertensive, angiotensin converting enzyme
Action: Selectively suppresses renin-angiotensin-aldosterone system; inhibits ACE; prevents conversion of angiotensin I to angiotensin II
Used to treat high blood pressure and heart failure |
Lisinopril; Hydrochlorothiazide | Func. class.: Antihypertensive, Diuretic
Chem class.: Enalaprilat lysine analog, Thiazide
inhibits ACE; prevents conversion of angiotensin I to angiotensin II
Used to treat high blood pressure and heart failure |