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Cardio
| Term | Definition |
|---|---|
| Quinapril | Func. Class: Antihypertensive Chem. Class: Angiotensin-converting enzyme (ACE) inhibitor Action: reduce blood pressure |
| Ramipril | Func. Class: Antihypertensive Chem. Class: ACE inhibitor Action: Reduces high blood pressure |
| Losartan Potassium | Func. Class: Antihypertensive Chem. Class: Angiotensin II receptor (type AT1) Action: receptor blocker for high blood pressure |
| Losartan Potassium/Hydrochlorothiazide | Func. Class: Diuretic Chem. Class: Angiotensin II receptor Action: Angiotensin II receptor blocker (ARB) + thiazide diuretic. |
| Olmesartan Medoxomil | Func. Class: Antihypertensive Chem. Class: Angiotensin II receptor (type AT1) antagonist Action: Angiotensin II receptor blocker (ARB) for blood pressure |
| Valsartan | Func. Class: Antihypertensive Chem. Class: Angiotensin II receptor antagonist (type AT1) Action: Angiotensin II receptor blocker (ARB) for blood pressure |
| Valsartan/Hydrochlorothiazide | Func. Class: Antihypertensive Chem. Class: Class: Angiotensin II receptor antagonist (type AT1) and thiazide diuretic for blood pressure Action: Angiotensin II receptor blocker (ARB) for blood pressure and diuretic |
| Diltiazem Hydrochloride | Func. Class: Calcium channel blocker and antihypertensive drug Chem. Class: benzothiazepine Action: Calcium channel blocker used to lower blood pressure |
| Verapamil Hydrochloride | Func. Class: Calcium channel blocker and antihypertensive Chem. Class: Diphenylalkylamine Action: is to block voltage-dependent calcium channels |
| Amlodipine Besylate | Func. Class: Antianginal calcium channel blocker, antihypertensive Chem. Class: Dihydropyridine Action: Dihydropyridine calcium channel blocker for high blood pressure |
| Amlodipine Besylate/Benazepril | Func. Class: Antianginal calcium channel blocker, antihypertensive Chem. Class: ACE inhibitor Action: dihydropyridine calcium channel blocker with ACE inhibitor for high blood pressure |
| Nifedipine | Func. Class: Calcium channel blocker, antihypertensive Chem. Class: Dihydropyridine Action: Dihydropyridine calcium channel blocker to reduce blood pressure |
| Hydralazine Hydrochloride | Func. Class: Antihypertensive, vasodilator Chem. Class: Phthalazine Action: Directly relaxes vascular smooth muscle to cause peripheral vasodilation, decreasing arterial BP and peripheral vascular resistance. |
| Isosorbide Mononitrate | Func. Class: Antianginal, vasodilator Chem. Class: Nitrate Action: a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump. Can help with chest pain |
| Nitroglycerin | Func. Class: Coronary vasodilator, anyianginal Chem. Class: Nitrate Action: decreses pre/afterload which decreases left ventricular end-diastolic pressure and reduce high blood pressure |
| Atorvastatin | Func. Class: Antilipidemic Chem. Class:HMG-CoA reductase inhibitor Action: inhibits HMG-CoA reductase enzyme, which reduces cholesterol synthesis leads to plaque regression |
| Lovastatin | Func. Class: Antilipemic Chem. Class: HMG-CoA reductase inhibitor Action: inhibits HMG-CoA reductase which reduces cholesterol synthesis |
| Pravastatin Sodium | Func. Class: Antilipemic Chem. Class: HMG-CoA reductase inhibitor Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
| Rosuvastatin Calcium | Func. Class: Antilipemic Chem. Class: HMG-CoA reductase inhibitor Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
| Aspirin | Func. class.: Opiate analgesic Chem. class.: Semisynthetic derivative Action: Inhibits ascending pain pathways in CNS, increases pain threshold, alters pain perception Used: mod-severe pain |
| Furosemide | Func. class.: Loop diuretic Chem. class.: Sulfonamide derivative ACTION: Ascending loop of Henle in kidney, inhibiting reabsorption of electrolytes; inc. excretion of K+ in the distal tubule of the kidney; responsible for slight antihypertensive effec |
| Chlorthalidone | Func. class.:Diuretic Action: Treats high blood pressure |
| Hydrochlorothiazide | Func. class.: Diuretic, antihypertensive Chem. class.: Thiazide, sulfonamide derivative ACTION: acts on the distal tubule in the kidney, increasing excretion of sodium, water, chloride, and potassium USES: Edema, hypertension, diuresis, CHF |
| Hydrochlorothiazide; Triamterene | Func. class.: Diuretic, antihypertensive Chem. class.: Thiazide, sulfonamide derivative ACTION: acts on the distal tubule in the kidney, increasing excretion of sodium, water, chloride, and potassium USES: Edema, hypertension, diuresis, CHF |
| Spironolactone | Func. class.: Potassium-sparing diuretic Chem. class.: Aldosterone antagonist ACTION:Competes w/ aldosterone at receptor sites in distal tubule in the renal system, causing excretion of sodium chloride, water, retention of potassium, phosphate |
| Potassium | Func. class.: Electrolyte, mineral replacement Chem. class.: Potassium ACTION: used for adequate transmission of nerve impulses & cardiac contraction, renal function, intracellular ion maintenance |
| Doxazosin Mesylate | Func. class.: Peripheral α-adrenergic blocker, antihypertensive Chem. class.: Quinazoline ACTION: dilates peripheral blood vessels, PBV resistance lowers, reduction in BP results from blocked peripheral α-adrenergic receptors |
| Terazosin | Func. class.: Antihypertensive Chem. class.: α-Adrenergic blocker (peripherally acting) ACTION: dilates peripheral blood vessels, PBV resistance lowers, reduction in BP results from blocked peripheral α-adrenergic receptors |
| Clonidine | Func. class.: Antihypertensive, centrally acting analgesic Chem. class.: α-adrenergic agonist Action: Inhibits sympathetic vasomotor center in CNS, reduces impulses in Sympathetic NS; BP, pulse rate, cardiac output decreased |
| Propranolol Hydrochloride | Func. class.: Antihypertensive, antianginal, antidysrhythmic (class III) Chem. class.: β-Adrenergic blocker ACTION:Nonselective β-blocker with negative inotropic, chronotropic, dromotropic properties |
| Propranolol Hydrochloride/Hydrochlorothiazide | Func. class.: AHTN, antianginal, antidysrhythmic ACTION:Nonselective β-blocker w/ negative inotropic, chronotropic, dromotropic properties Func class: Diuretic, AHTN ACTION: acts on the distal tubule in the kidney, inc. excretion of Na+, h2o, Cl, and K |
| Atenolol | Func. class.: Antihypertensive Chem. class.: β-Blocker; β1-, β2-blocker (high doses) slows conduction of AV node, dec. HR, dec. O2 consumption in myocardium; dec. renin-aldosterone-angiotensin system at high doses, |
| Atenolol; Chlorthalidone | Antihypertensive Action decreases heart rate and blood pressure Func. class.:Diuretic Action: Treats high blood pressure |
| Simvastatin | Func. Class: Antilipemic ChemClass: HMG-CoA reductase inhibitor Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
| Fenofibrate | Func. Class: Antilipemic Chem. Class: Fibric acid derivative Action: lowers triglyceride and cholesterol levels |
| Gemfibrozil | Func. Class: Antilipemic Chem. Class: fibric acid derivative Action: lowers triglyceride and cholesterol levels |
| Ezetimibe | Func. Class: Antilipemic Action: decreases cholesterol/triglyceride levels |
| Ezetimibe; Simvastatin | Func. Class: Antilipemic Chem. Class: HMG-CoA reductase inhibitor Action: used to lower blood cholesterol and reduce the risk of heart attack, stroke and death |
| Warfarin | Func. Class: Anticoagulant Action: prevention of clotting |
| Dabigatran Etexilate Mesylate | Func. Class: Anticoagulant Chem. Class: Thrombin inhibitor Action: Decreased thrombus formation/extension |
| Rivaroxaban | Func. Class: Anticoagulant Chem. Class: Factor Xa inhibitor Action: oral or novel anticoagulant that prevents DVT, stroke and systemic embolism |
| Clopidogrel Bisulfate | Func. Class: Platelet aggregation inhibitor Chem. Class: Thienopyridine derivative Action: decreases possibility of stroke, MI by decreasing platelet aggregation |
| Digoxin | Func. Class: Inotropic antidysrhythmic cardiac glycoside Chem. Class: Digitalis preparation Action: inhibits Na--K+ ATPase which increase calcium for contractile proteins=increases cardiac output/decreased edema/pulse |
| Amiodarone Hydrochloride | Func. Class: Antidysrhythmic (Class III) Chem. Class: Iodinated benzofuran Action: decreased amount/severity of ventricular dysrhythamias |
| Metoprolol | Func. class.: Antihypertensive, antianginal Action: Lowers B/P; reduces elevated renin plasma levels; blocks β2-adrenergic receptors in bronchial |
| Carvedilol | Func. class.: Antihypertensive Action: decreases cardiac output, exercise-induced tachycardia, reflex orthostatic tachycardia; causes reduction in peripheral vascular resistance & vasodilatation |
| Nebivolol Hydrochloride | Func. class.: Antihypertensive slows conduction of AV node = decreased HR, decreases O2 consumption, decreases renin-aldosterone-angiotensin system at high doses |
| Benazepril Hydrochloride | Func. class.: Antihypertensive Suppresses renin-angiotensin-aldosterone system; inhibits ACE, preventing conversion of angiotensin I to angiotensin II |
| Enalapril Maleate | Func. class.: Antihypertensive (used to treat high blood pressure and heart failure) inhibits ACE; prevents conversion of angiotensin I to angiotensin II, resulting in dilatation of arterial and venous vessels |
| Lisinopril | Func. class.: Antihypertensive, angiotensin converting enzyme Action: Selectively suppresses renin-angiotensin-aldosterone system; inhibits ACE; prevents conversion of angiotensin I to angiotensin II Used to treat high blood pressure and heart failure |
| Lisinopril; Hydrochlorothiazide | Func. class.: Antihypertensive, Diuretic Chem class.: Enalaprilat lysine analog, Thiazide inhibits ACE; prevents conversion of angiotensin I to angiotensin II Used to treat high blood pressure and heart failure |
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lvnpharm
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