Term | Definition |
Alprazolam(Xanax) and lorazepam(Ativan): | rapid addiction, prolonged sedation effects, potential for confusion and falling. Short acting benodiazapine. |
Amitriptyline (Elavil): | Strong anticholinergic and sedating properties, little effect on depression, with low doses, sometimes effective for neurogenic pain |
Tagament: | Significant for ADR with many substances and medications |
Cyclobenzaprine (Flexeril): | Anticholinergic side effects sedation, weakness |
Diazaepam (Valium): | long-acting benzodiazepines produce prolonged sedation, increasing fall risk and confusion risk |
Dipyridamole (Persantine): | orthostatic hypotension |
Meperidine(Demerol): | Metabolite accumulation in elderly, can cause tremors and seizures. |
Oxybutynin (Ditropan): | Strongly anticholinergic, confusion |
Propoxyphene and combinations containing propoxyphene (Darvon and Darvocet): | No analgesic advantage over acetaminophen. |
Temazepam (Restoril): | confusion, prolonged half-life |
Indomethacin (Indocin): | Produces the most CNS effects of the NSAIDS |
Digoxin (Lanoxin): | Adverse effects may result from decreased renal clearance; dose should not exceed 0.125mg/day except when treating arrhythmia |