Question | Answer |
MOA alpha-adrenergic drugs
used for hypotension | activates SNS, contraction of smooth muscle (artieris and extremeties); vasoconstriction, contraction of sphincter, liation of pupils, decrease GI, relaxation of of bladder, targets alpha adrenergic receptors |
metaraminol | Aramine |
Norepinephrine | Levophed |
Tetrahydrozoline | Visine |
alpha-adrenergic drugs | metaraminol - Aramine
norepinephrine - Levophed
tetrahydrozoline (Visine) |
MOA Beta-adrenergic Drugs
used for cardiac stimulation and asthma | stimulation of the heart (beta 1) and bronchodilation (beta 2)Beta adrenergic is similar to symphatomimetics |
MOA: Non-selective beta-adrenergics | target more than one receptor site (beta 1 and beta 2)dopamine - Intropin, and epinephrine -Adrenaline |
dopamine | Intropin |
epinephrine | Adrenaline |
MOA of selective beta-adrenergics | only stimulate beta 2 receptors without causing excessive stimulation of beta 1. albuterol - Proventil, ventolin |
albuterol | Proventil, ventolin |
MOA alpha blockers | alpha blockers compete with NE for binding to the alpha adrenergic receptors; since the major alpha organ is the blood vessels, vasolidation and lowering of blood pressure occurs. Used for hyprtension
prazosin - minipress
doxazosin - Cardura |
prazosin | minipress |
doxazosin | Cardura |
Adverse effects of alpha blockers drugs | v BP , Nasal congestion, ^ GI, constriction of pupils |
MOA selective Beta blockers
atenolol - Tenormin, etoprolol - Lopressor
Used for hpotension | bind to beta 1 receptors and block effects of EPI and NE. Used for hypertension, angina, arrhythmias |
atenolol | Tenormin |
etoprolol | Lopressor |
MOA Non-selective beta blockers
nadolol - Corgurd, proprananolol - Inderal
Used for hypotension | block beta 1 and beta 2 receptors on smooth muscle |
Adverse effects of beta blockers | N/V, diarrhea, bradycardia, CHF, cardiac arrest |
nadolol | Corgurd |
proprananolol | Inderal |
MOA cholinegics
bethanechol -Urecholine | mimic the actions of Ach at the receptors. used for urinary retention |
Adverse effects of cholinergics | excessive stimulation of Parasympathetic; N/V, diarrhea, blurred vision, seating, tremors, bronchoconstriction, bradycardia, hypotension |
Urecholine | Urecholine |
MOA anticholinegics | block the cholinergic binding sites of Ach; used for asthma |
atropine | antidote to cholinergic drugs |
Adverse effects of beta-adrenergics | overstimulation of heart, restlessness, tremors, anxiety, arrythmias |
Adverse effects of alpha adrenergics | excessive vasoconstriction of blood vessels; hypertension, hypertensive crisis. |