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Meds for 5, 6
| Question | Answer |
|---|---|
| MOA alpha-adrenergic drugs used for hypotension | activates SNS, contraction of smooth muscle (artieris and extremeties); vasoconstriction, contraction of sphincter, liation of pupils, decrease GI, relaxation of of bladder, targets alpha adrenergic receptors |
| metaraminol | Aramine |
| Norepinephrine | Levophed |
| Tetrahydrozoline | Visine |
| alpha-adrenergic drugs | metaraminol - Aramine norepinephrine - Levophed tetrahydrozoline (Visine) |
| MOA Beta-adrenergic Drugs used for cardiac stimulation and asthma | stimulation of the heart (beta 1) and bronchodilation (beta 2)Beta adrenergic is similar to symphatomimetics |
| MOA: Non-selective beta-adrenergics | target more than one receptor site (beta 1 and beta 2)dopamine - Intropin, and epinephrine -Adrenaline |
| dopamine | Intropin |
| epinephrine | Adrenaline |
| MOA of selective beta-adrenergics | only stimulate beta 2 receptors without causing excessive stimulation of beta 1. albuterol - Proventil, ventolin |
| albuterol | Proventil, ventolin |
| MOA alpha blockers | alpha blockers compete with NE for binding to the alpha adrenergic receptors; since the major alpha organ is the blood vessels, vasolidation and lowering of blood pressure occurs. Used for hyprtension prazosin - minipress doxazosin - Cardura |
| prazosin | minipress |
| doxazosin | Cardura |
| Adverse effects of alpha blockers drugs | v BP , Nasal congestion, ^ GI, constriction of pupils |
| MOA selective Beta blockers atenolol - Tenormin, etoprolol - Lopressor Used for hpotension | bind to beta 1 receptors and block effects of EPI and NE. Used for hypertension, angina, arrhythmias |
| atenolol | Tenormin |
| etoprolol | Lopressor |
| MOA Non-selective beta blockers nadolol - Corgurd, proprananolol - Inderal Used for hypotension | block beta 1 and beta 2 receptors on smooth muscle |
| Adverse effects of beta blockers | N/V, diarrhea, bradycardia, CHF, cardiac arrest |
| nadolol | Corgurd |
| proprananolol | Inderal |
| MOA cholinegics bethanechol -Urecholine | mimic the actions of Ach at the receptors. used for urinary retention |
| Adverse effects of cholinergics | excessive stimulation of Parasympathetic; N/V, diarrhea, blurred vision, seating, tremors, bronchoconstriction, bradycardia, hypotension |
| Urecholine | Urecholine |
| MOA anticholinegics | block the cholinergic binding sites of Ach; used for asthma |
| atropine | antidote to cholinergic drugs |
| Adverse effects of beta-adrenergics | overstimulation of heart, restlessness, tremors, anxiety, arrythmias |
| Adverse effects of alpha adrenergics | excessive vasoconstriction of blood vessels; hypertension, hypertensive crisis. |