Question | Why ? Drug? | SE |
Dwarfism [why? Drug? SE?] | Why: Deficiency of GH
Drug: Somatropin [Recombinant human growth hormone]
hints: 小人食數碼脆片->變大 | Glycaemia
hypothyrodism (reduces T3 production)
Edema (retention of electrolytes)
Headache |
Acromegaly 肢端肥大症 /
Gigantism 巨人症 [why? Drug? SE? ] | Why: Hypersecretion of GH
Drug: Octreotide (analog of sonatostatin)
M: inhibit secretion of GH from anterior pituutary)
hints: 十月巨人生膽石 | Gallstones*
Postprandial 餐后的 hyperglycaemia
(inhibit insulin also) |
Acromegaly 肢端肥大症 /
Gigantism 巨人症 [why? Drug? SE? ] | Why: Hypersection of GH
Drug: Pegvisomant
hints : 肥大Peggy so 猛,肝識飛 | Alter liver function
Flu syndrome |
Addison's disease
[why? Drug? SE? ] | Why: Deficiency of ACTH
Drug: Hydrocortisol + Fludrocortisone (analog of aldosterone)
hints' Addison 太輕鬆, 要俾壓力佢 | Cushing's syndrome:
fat, hyperglycaemia, osteoporosis |
Cushing's Syndrome /
Hyperaldosteronism
[why? Drug? SE?] | Why: Hypersecretion of cortisol
Drug: Trilostant [三撈屎丁] , metyrapone [Mary話封]
hints:壓力Mary 話封左個三(舊)撈屎丁 | Hypotension,rash |
Hyperprolactinemia
(Galactorrhea, hypogonadism 生殖官能不良)
[why? Drug? SE?] | Why: hypersecretion of prolactin
Drug: Bromocriptine , carbagoline
[漏奶, 保姆會癲,卡巴去線] | Postural hypotension, constipation |
Diabetes insipidus 尿崩症
[每個鐘去次小便,常口乾]
[Why? Drug? SE?] | Why: Decificieny of ADH(Antidiuretic Hormone)(吸水能力低,成日放hypotonic 既尿)
Drug: vasopressin(same to ADH) /desmopressin (analong of ADH)[act on V2 receptor] | SE:Fluid retention.
Vasopressin 血管加壓素]: spasm of coronary artery (angina)
[desmopressin: x act on V1 receptor] |
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