Question | Answer |
Who is ACOG | American Congress of Obsteticians and Gynecologist |
What is their opionion on pain | Relief uring labor #118 1993 states that ....maternal request is sufficient justification for pain relief during labor. |
Join statement by ACOG and ASA was approve when | was approved by ASA house of delegates on oct 13, 1999. |
what was the statements of ACOG and ASA | Labor results in severe pain for many women. There is no circumstance where it is considered acceptable for a person to experience untreated severe pain, amennable to safe intervention. |
Regional anesthesia for childbearing is | Philosophy->
-safe
participatory |
1st stage of labor is | Pressure on nerve endings of the uterus
Contraction of an ischemic myometrium & cervix
Vasoconstriction
Inflammatory changes
Dilation of the cervix and lower uterine segment |
Who is ACOG | American Congress of Obsteticians and Gynecologist |
What is their opionion on pain | Relief uring labor #118 1993 states that ....maternal request is sufficient justification for pain relief during labor. |
Join statement by ACOG and ASA was approve when | was approved by ASA house of delegates on oct 13, 1999. |
what was the statements of ACOG and ASA | Labor results in severe pain for many women. There is no circumstance where it is considered acceptable for a person to experience untreated severe pain, amennable to safe intervention. |
Regional anesthesia for childbearing is | Philosophy->
-safe
participatory |
1st stage of labor is | Pressure on nerve endings of the uterus
Contraction of an ischemic myometrium & cervix
Vasoconstriction
Inflammatory changes
Dilation of the cervix and lower uterine segment |
what causes 1st stage perception? | First stage of labor is the result of dilation, distention, and stretching of the cervix and lower uterine segment during contraction |
Perceptions during 2nd and 3rd stages of labors are? | Traction on the pelvic peritoneum & uterine ligaments
Tension on bladder and rectum
Tension on ligaments, fascia and muscles of the pelvis
Pressure on lumbosacral plexus |
What kind of pain during 2nd stage of labor | Somatic pain. This affect the pudental nerves: S2-4 |
What dermatones cover the perineum? | S2-4 |
What are the perception of labor experience? | Factors influencing severity of pain:
pain tolerance
pain threshold
individual factors (intrapersonal, interpersonal, societal)
supportive structures
cultural factors |
Nonpharmacological pain relief are? | Method used to relief pain other than pharmacology. and this is prepared childbirth, hypnosis, tens, accupuncture, and alternative birthing options. |
Type of prepared childbirth are? | Grantly Dick-Reed (Childbirth without Fear)
Lamaze (Psychoprophylaxis)
Fredrick Le Boyer (Birth without Violence |
TENS | transcutaneous electrical nerve stimulation |
What the advantage of systemic analgesic for labor | Ease of use
staffing
no IV required (IM)
Minimal monitoring
few complications |
what are disadvantages for systemic analgesic for labor | Effectiveness
Depression
Respiratory decreases
N/V
Fetal depression |
What are some opioids used during labor | Fentanyl, Sufentanil, Alfentanil, Demerol, and Morphine (of historical interest only) |
Potency: | morphine=1; demerol=0.1; alfenta=10-25; fentanyl=75-125; sufenta=500-1000 (S & M, p.113) |
Agonist/antagonist | Nalbuphine (Nubain), Butorphanol ( Stadol), Pentazozine (Talwin). |
Agonist/antagonist potency | N & Z, p. 157; S & M, p. 120; Chestnut, p. 315-6
Potency: nubain- 0.7-0.8; stadol- 5; Talwin- 30-60 mg = 10 mg morphine
Note: Stadol is out of favor for use in some OB settings due to a 75% incidence of transient sinusoidal fetal heart patterns (consid |
Sedatives | Phenothiazine; benzodiazepines, and butyrophenones |
What are examples of phenothiazines | - thorazine, phenergan; |
What are examples of benzo | Versed, valium |
What are example of butyrophenones | Haldol and droperidol |
Anticholinergic | Atropine, scopolamine and glycopyrolate |
Does glycopyrolate cross BBB | No it does not cross the BBB |
Some peripheral nerve blocks for L&D are | Field block; Pudendal nerve block, paracervia block ->with complications of local anesthesia toxicity and fetal brady cardia |
What are complication of peripheral nerve block in pregnant women | local anesthesia toxicity and fetal bradycardia. |
What is the "gold standard" of invasive intervention? | Epidural |
Why Epidural | Grateful patient
Excellent analgesia
May improve dysfunctional labor
Can be raised for C-Section
Minimizes risk of
-maternal aspiration
-fetal depression
Lower VAS pain scores
Inc oxygen sat
Higher fetal scalp pH
BUT… no signif diffe in Apgar sc |
What type of solution is used in epidural and intratechal space? | Preservative free solution |
VAS | Visual analogue score |
Why do you need to asked OB anesthetist their protocol for epidural drugs | because loading dose and infusion rate may be different at different clinical sites or hospital. |
Epidural ( one[of many] dosing rationales | Find the space!
Loading dose:
20ml of 1/8 (0.125)% bupivacaine +
100mcg fentanyl.
Give in divided doses
Infusion:
50ml 1/16 (0.0625)% bupivacaine +
100mcg fentanyl
infuse at 10-15 ml/hr |
What are Epidural complications | Hypotension
Total spinal
Local anesthetic toxicity
Headache
Local site pain |
Epidural anesthesia contraindications | Patient refusal
Coagulopathies
Infection at injection site
Uncorrected hypovolemia |
Regional anesthesia contraindication | Significant fetal distress |
Subarachnoid block | Possible for delivery
but not for labor
True “saddle” vs. low spinal
Administration position
upright vs. lateral position |
right lateral decubitus position for SAB | ensures that all nerves get bathed with hyperbaric LA solution when pt placed in LUD prior to CS |
Intrathecal Analgesia ( with or without any local) | 25mcg Fentanyl +
100-150 mcg Morphine
(astromorph/duramorph) |
What happen with ITA morphine | Itching, N&V, and urine retention |
what are the advantages of intrathecal analgesia (ITA) | Excellent analgesia, No sympathetic block and patient can ambulate |
Combine techniques (the best of both world) are | Performed ITA for labor and also place an epidural cath for use if needed later. |
A word of warning? | Beware of VBACS ( vaginal birth after c/s).
Be prepared for emergent intervention |
What are the advantages for epidural analgesia for L&D | awake patient
avoids risks of somulence
↓ hypoxia
↓ hypercarbia
↓ ASPIRATION
continuous
ready for C/S
safety |
What are the disadvantages of epidural analgesia for L&D | Maternal affects
Fetal affects
? Prolonged labor
? ↑ C/S RATE
? Motor block
? Bed rest |
Epidural analgesia effects on labor | Potential Effects:
UTERINE MUSCLE
SKELETAL MUSCLE
? explusive forces
? ability to change positions
pelvic floor muscle tone
? Operative deliveries |
hemodynamics with epidural analgesia | Indirect effects:
uteroplacental perfusion
oxytocin metabolism
circulatory reflex depression |
Technique issues are | Lateral Vs sitting
LOR tech (air Vs saline, glass Vs plastic)
Catheter direction
How far to insert catheter |
What is LOR | loss of resistance; Catheter should be inserted about 3-5cm |
Where is the catheter? | Do you ever REALLY know?
Aspiration
-CSF
-blood
Test dose
-what
-why
Monitoring |
Is that CSF | Amount of return and the temperature |
S&S suggesting that it may be a SAB (Spinal anesthesia block | Signs are Sensory block; Motor weakness; and
Hypotension
Symptoms are Warm sensation; Pain relief and
Numbness |
Test dose | Epinephrine & local
Monitor HR & B/P
Alternatives (eg fentanyl)
3 ml local anesthetic with 1:200,000 epinephrine (15 mcg/ml). Brown, p340 |
What are pregnancy issues with epidural? | Epidural space volume changes
Venous sinuses
Physical size
Positioning (ICV syndrome) |
What are the common Local agent | Bupivacaine
Lidocaine
2,3-Chloroprocaine
Opiates usually added |
WDosing Issues are | Incremental Vs continuous
Infusion formulae
“Top off” doses (5 mL increments) |
Problem Management with Epidural | “ wet tap “
Blood in catheter
Hypotension
High block
Motor block
Inadequate analgesia |
Epidural failure | ? Drug dose, ? Catheter placement, and ?time |
General Anesthesia during labor | Fortunately, seldom used for vaginal delivery
M & M : worse than with regional anesthesia |
Proxima Causa Mortae | Aspiration -
-3X more common
FAILED INTUBATION:
-general surgery - 4.5/10,000
-OB & C-Sections - 35/10,000 |
Advantages of GETA | Speed of induction
Reliability
Control
Avoidance of hypotension |
Potential GETA problems | Maternal aspiration
Airway difficulties
Awareness
Stress response
Increased blood loss |
What are the indications for GETA | Acute fetal distress
Hemodynamic instability
Cardiac disease
Coagulopathy
Sepsis
Failed regional techniques |
If the stomach is full ( as they all) | Metoclopramide 10 mg IV +
Randetidine 50 mg IV +
Na Citrate 30 ml PO |
GETA techniques | Airway assessment
Know (and practice!) failed intubation procedures
Difficult airway cart available
Staff education
Aspiration prophylaxis |
GETA considerations are | Positioning, monitors and preoxygination |
Why preoxygenate? | alterations in respiratory physiology.
decrease apnea to hypoxia time
denitrogenation |
Pretreat with NDNMBD | for fasiculations after suc.
Myalgia
gastric pressure |
Induction Agents | Sodium thiopental
Methohexitol
Ketamine
Etomidate
Propofol
Midazolam |
GETA Concerns | Hyperventilation:
-↓ uterine blood flow
-Left shift of maternal O-HDC
-↓ ability to delivery oxygen to baby
Neonatal depression:
-time from induction to delivery is THE important factor |
General anesthesia is not routinely used for elective cesarean section.(true or false) | True: because it typically reserve for obstetrical emergencies |
What are major indications for c/s | Labor unsafe for mother and fetus.
Dystocia
Immediate or emergent delivery necessary |
Indications for general anesthesia are? | Contraindications to regional anesthesia (e.g) coagulapathy
Fetal distress
Failed regional block
Patient refusal |
When time is limiting factor then GA is | When time is a limiting factor, general anesthesia is sometimes necessary because it offers speed of induction, reliability, controllability, and avoidance of sympathectomy induced hypotension |
Problems associated with GA are? | Problems associated with general anesthesia principally involve failed intubation and aspiration. Physiologic changes of pregnancy increase the incidence of failed intubations and aspiration |
Preparation for GA | Airway evaluation:
-Vital to identify patients with problematic airways early
-Physical factors and physiologic changes of pregnancy may complicate ET intubation
Aspiration prophylaxis
Experienced personnel and backup plans
Fetal considerations |
Conduct of GA | Basic prep
Positioning and monitoring
Maternal preoxygenation
Induction:
-RSI with cricoid pressure
-Intubate with 6.0-7.0 cuffed endotracheal tube
Maintenance
Emergence:
-Patient extu awake with airway reflexes intact
-if pt is unstable, ETT rem |
The Obese parturient consideration: | Considerations:
BMI = wt (kg) / ht (m)2
Morbid obesity defined as body weight more than twice the ideal weight, or BMI greater than 35 |
The obese parturient is at greater risk for medical diseases: | Cardiovascular system
Respiratory system
Endocrine and metabolic system
Gastrointestinal system |
In the Obese parturient with difficult airway | every effort should be made to initiate an early regional anesthetic
Cesarean section rate is significantly higher
Anxiolytic drugs and opioids ought to be administered with great caution in the morbidly obese parturient |
Airway considerations for the obese parturient | -Limited flexion and mouth opening
-Narrowed view of pharyngeal opening
-Higher incidence of failed intubation
-Proper positioning of the head and neck may facilitate endotracheal intubation |
Optimal positioning for the obese parturients | Proper positioning may facilitate endotracheal intubation; elevation of shoulders, flexion of the cervical spine, and extension of atlanto-occipital joint. |