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flow properties
not very good don't waste a lot of time
| Question | Answer |
|---|---|
| powders with low angle of repose flow | freely |
| powders with high angle of repose flow | poorly |
| very fine or very large flow freely | large |
| particles size in the subsieve ragne can be obtained by ? and expressed a ? | gravity sedimentation/ stoke's law |
| equation for angle of repose | tan@=h/r |
| the closest packing is a | rhombohedral |
| 1-(true volume/bulk vol.) is = to | void |
| void times 100 = | porosity |
| weight of sample/volume of bulk | apparent density D=m/v |
| weight of sample/volume of true volume | true density ( the density without void) |
| volume of bulk/weight of sample | bulkiness |
| what does it mean to have a low apparent density | for the amount of volume it takes up, it doesn't weight much |
| bulk volume is | what you see or the volume occupiced by a powder placed in a graduated cylinder |
| the formula for bulk is | true volume of the solid + void |
| how do you find true volume | plug actual mass into the true density equation |
| powders wiht low apparent density and a large bulk volume are considered | light |
| powders with high apparent density and small bulk volum are | heavy |
| what is a good indicatior of packagina | comparing app density vs true density |
| medicated powders are for local effects, systemic effects or both | local and systemic |
| medicated powders are for internally, external,inhaled or what combination | external and internal and inhaled |
| crstalline alpha lactose monohydrate | inert propellant and diluent to aid the frmulations flow properties adn to protect the poweder from humidity |
| what method is used for potent substance to make individual dosing units | geometric dilution medthod |
| what method is used for non potent drugs | block and divide |
| headache powders, powdered laxative, douche powders are examples of bulk or divided powders | divided powders |
| a transparent waterproof paper | waxed paper |
| a glazed, transparent paper, also with limited moisture resistance | glassine |
| a thin semi opaque paper with limited moisture resistance | vegetable parchment |
| simple powder paper | bond paper |
| fluid massing or fluid bed processing is type of wet or dry | wet |
| what is the most common type of granulation | dry |
| compression of powder into large tablets is | slugging which is a dry method |
| when fine powders are forced between counter rotating rolls to form solid compact or sheet then reduced in size using mills or sieve granulators | roll compactor by dry granulation |
| what advantage do granules have over powders | flow better,more commonly used in tablets, more stable to the effects of atmospheric humidity, less likely to cake or harden upon standing, more easily wetted by liquids |
| examples of granulated products | lactines granules for diarreah due to antibiotic therapy, zantac efferdose tablets |
| effervescent salts are granules of what types of powders (like coarse or fine) | coarse to very coarse |
| effervescent salts contain medicinal agents in a dry mixture usually composed of | sodium bicarbonate, citric acid, and tartaric acid |
| when adding water to effervescent what is liberated to result in effervescent | carbon dioxide |
| in the dry method for preparing effervescent granules what acts as the binding agent | the one molecule of water present in each molecule of citric acid |
| in the wet method the source of binding agent is the | water added to alcohol as teh moistening agent forming the pliable mass for granulation |
Created by:
lainylaina
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