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excepients
ceutics
| Excipent | type of exceptient | used for |
|---|---|---|
| cystalline alphalactose monohydrate | propellant and pharmaceutical diluent | aid in the formulation's flow properties and protects the powder from humidity in aerosol powderes |
| titianum dioxide | opaque agent | (blank) |
| FD&C and D&C | dyes | for color |
| silica gel | desiccant material | used to protect against moisture |
| clay | desiccant material | to protect against moisture |
| activated charcoal | desiccant material | used to protect against moisture |
| lactose | diluent | inert filler to create desired bulk, flow properties,and compression characteristics of tablets and capsules |
| kaolin | diluent | inert filler to create desired bulk, flow properties,and compression characteristics of tablets and capsules |
| mannitol | diluent | inert filler to create desired bulk, flow properties,and compression characteristics of tablets and capsules |
| microcrystalline cellulose | diluent | inert filler to create desired bulk, flow properties,and compression characteristics of tablets and capsules |
| sodium starch glycolate | disintergrant | promote distruption of the capsule content into smaller pieces |
| sorbitol | diluent | inert filler to create desired bulk, flow properties,and compression characteristics of tablets and capsules |
| pregelatinized starch | disintegrant | promote distruption of the capsule content into smaller pieces |
| croscarmellose | disintegrant | promote distruption of the capsule content into smaller pieces |
| mineral oil | lubricant | used in tablet formulations to reduce friction during tablet compression |
| colloidal silica | glidant | used in tablet and capsule formulations to improve flow properties of the powder mixture |
| cornstarch | glidant | used in tablet and capsule formulations to improve flow properties of the powder mixture |
| sodium lauryl sulfate | surfactant suface active agent | substances that absorb to surfaces or inter faces to reduce surface or interfacial tension. may be used as weeting agents, detergetns or emulsifying agents |
| fumed silican dioxide | lubricant or glidant | enhance flow poperties |
| magnesium carbonate | diluent or adsorbent | adsorb any liqu. material that may have formed |
| light magnesium oxid | diluent and absorbent | absorb liqu material that may have formed when mixing two solids together |
| methylparaben | antifungal preservative | used in soft gelatin capsules to prevent growth |
| propylparaben | antifungal preservative | prevent growth |
| sucrose and lactose | diluents | in table triturates |
| polyethlene gloycol ointment | water soluble base | (blank) |
| hydrophilic ointment | water removable base or water washable base | can absorb serous discharges mostly water |
| hydrophilic petrolatum | absorption base | permit the incorporation of aqueous solutions resulting in the formation of water-in-oil not washable in water but can absorb water |
| lanolin | absorption base | are water-in-oil emulsions that permit the incorporation of addional quantities of aqueous solutions not washable in water but can absorb water |
| petrolatum "vaseline" or white petrolatum | oleaginous base | cannot absorb or contain water and are not washable in water |
| yellow or white ointment | oleaginous base | cannot absorb or contain water and are not washable in water |
| ointment bases are use for | lubricants in | medicated ointement |
| unmedicated ointments are used for | protectants, emollients lucbricants | (blank) |
| polyethlyene, | inert plastic material | (blank) |
| polyvinyl acetate | inert plastic material | (blank) |
| polymethacrylene | inert plastic material | (blank) |
| gelatin | commonly used wall forming material in microencapsulated drug | potassium chloride is an example |
| ethly cellulose and plasticizer as | coating material of aqueous coating systems | eg. aquacoat( FMC corporation) Surelease ( colorcon) |
| beads used in extended release formulation are made of | sugar and starch or microcystaline cellulose | (blank) |
| granules that get coated for exten. rel. are made of lipid material like | beeswax, carnauba wax or a cellulosic material like ethylcellulose | (blank) |
| cellulose acetate phthalate | enteric coatings | (blank) |
| pharmaceutical shellac | enteric coating | to dissole at ph of 4.8 or greater |
| hydroxypropy methylcellulose phthalate | enteric coating | dis at pH of 4.8 or greater |
| polyvinyl acetate phthalate | enteric coating | pH 4.8 or greater |
| beeswax | gloassant | provides luster to the tablet without a separate polishing operation |
| example of volative solvent | alcohol mixed with acetone | allows spread of the other components over the tabets while allowing rapid evaporation to permit an effective yet speedy operation |
| vanillin | flavors and aromas | non aquenous film coating components |
| saccharin | sweetern | non-aquaeous film coating component |
| polyoxyethylene sorbitan derivatives | surfactants | enhances spreadability of the film during application |
| castor oil and diethyl phthalate aqueous | plasticizer | non queous film coating components |
| polyethylene glycol | alloying substnces | provides water solubility and permeablity to the film to ensure penetration by body fluids and therapeutic availability of the drug |
| cellulose acetate phthalate | film former | capable of producing smooth thin films applicable to a variety of tablet shapes non aqu flim coating |
| HPMC hydroxyporpylmethlycellulose | film forming polymer | aqueous film coating |
| diethyl phthalate | plasticizer | aqueous film coating |
| FD&C D&C iron oxide pigment | colorants and opacifier | aqueous |
| 30% ethylcellulose pseudolatex | commerical water based collodial coating | aquacoat ECD |