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Mucolytic
Generic name - Brand name/ Brand name to dose
| Question | Answer |
|---|---|
| Acetylcystine NAC | Mucomyst |
| Dornase Alfa | Pulmozyme |
| Mucomyst | 1-2 ml with Bronchodilator |
| Plumozyme | 2.5ml/2.5ml |
| MOA for Acetylcystine (NAC) | Breaks dloulfid bonds to make more viscus |
| MOA for Dornase Alfa | Digests DNA debris to make less sticky |
| Indications for Mucomyst | Bronchitis, non-productive cough |
| Indications for Pulmozyme | Cystic Fibrosis |
| Pulmozyme side effects | voice alterations, pharyngitis, laryngitis, rash, chest pain, conjunctivitis |
| Mucomyst side effects | nausea and vomiting |
| Mucomyst hazards | bronchospasm |
| pulmozyme hazards | none |
| Special precautions for Mucomyst | do not mix with antibiotics always give with beta agonist |
| Special precautions for dornase alfa | keep refrigerated must be used with approved neb. |