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Anti Viral Drugs

Pharmacology

QuestionAnswer
Seven class of antiviral drugs 1. inhibition of viral penetration and uncoating 2. inhibition of viral DNA polymerase
seven class continued 3. inhibition of viral dna and rna polymerase 4. inhibition of viral rna polymerase 5. inhibition of viral reverse transcriptase 6. inhibition of viral aspartate protease 7. inhibition of viral neuraminidase
inhibition of viral penetration and uncoating amantadine and rimantadine
inhibition of viral dna polymerase herpes medications-acyclovir, gancyclovir, famcyclovir, valacyclovir
inhibition of viral dna and rna polymerase foscarnet
inhibition of viral rna polymerase ribavirin
inhibition of viral reverse transcriptase zidovudine, didanosine, zalcitabine, stavudine, lamivudine, nevirapine
inhibition of viral aspartate protease (for aids) indinavir, ritonavir, saquinavir, nelfinavir
inhibition of viral neuraminidase zanamivir, oseltamivir
-ivir influenza
-ovir herpes
-avir aids
Indications for amantadine influenza and parkinson's disease
side effects for amantadine livedo reticularis and anticholinergic effects
method of action of ribavirin inhibits viral RNA polymerase and end capping of viral mRNA
What is the indication of Ribavirin? RSV
Side Effects of Ribavirin Teratogenic
MOA of Acyclovir Inhibits viral DNA polymerase
What mutation occurs that yields the organism resistant to acyclovir? decrease activity to viral thymidilate kinase
indications of acyclovir herpes and shingles ONLY
side effects of acyclovir nephropathy, neurotoxicity, and crystalluria
famciclovir and galacyclovir for herpes simplex, actions similar to acyclovir
use of ganciclovir? moa? cmv. similar to acyclovir BUT only in herpres, in CMV phosphotransferase.
side effects of ganciclovir leukopenia, thrombocytopenia, seizure in overdose, crystalluria
MOA of foscarnet inhibition of dna and rna polymerase
use of foscarnet cmv retinitis in AIDS patients
side effects of foscarnet nephrotoxicity
what medication with foscarnet causes severe hypocalcemia? iv pentamidine
moa of zanamavir and oseltamivir inhibits neuraminidases of influenza a and b
Created by: Samiaa76