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CPJE Preperation 2

QuestionAnswer
How often do you change Scopolamine patch? Q3 days
How do you use Scopolamine patch? Place behind the ear, 4H prior to travel
. What are the routes of admin for Epinephrine? IM, IV, SC
What is the DoC for cocaine overdose/hypertensive crisis? Phentolamine (Regitine)
BP goal for patients with CAD <130/80
BP goal for patients with CHF <120/80
What forms does Diuril come in? Chlorothiazide; tabs, susp, and IV (only thiazide in injectable)
What are the SE of Thiazides? Decreases Mg, K, Na, Cl. Increases Ca, Uric Acid, Glucose, and Lipids. Rash, Sulfa allergy, Preg Cat. D
Can you use Thiazides in patients with renal failure (CrCl<30mL/min)? No.
Can you use Thiazide-like diuretics for renal patients? Yes. Metolazone (Zaroxolyn, Mykrox) and Indapamide (Lozol).
What forms does Lasix come in? IV, IM, PO (tabs, oral solution)
SE for LOOP diuretics? Decrease in Mg, K, Ca, Na, Cl. Increase in Uric Acid, Lipids, Glucose. Rash, Lupus, Ototoxicity.
Can you use a LOOP diuretic for patients with Sulfa allergy? Yes, Ethacrynic acid (Edecrin).
What diuretics are used in Renal patients? LOOPS
List the Potassium-Sparing diuretics ATSE Amiloride (Midamor) Triamterene (Dyrenium) Spironolactone (Aldactone) Eplerenone (Inspra)
Aldactone Side Effects? Gynecomastia & Hirsutism (similar to ketoconazole & cimetidine)
What are the 2 diuretics used for end-stage HF? Spironolactone & Eplerenone
What is the dosing for Inspra? Contraindicated in what? HTN: up to 50mg BID. CHF: 50mg QD CI: K > 5.5mEq/L CrCl <30mL/min Strong inhibitors
SE for K-Sparing diuretics? Increase in K Decrease in Na Rash and Headache
What is the DoC (diuretic) for Hypercalcemia? Loops
What are the Beta Blockers used for CHF? Carvedilol (Coreg) Metoprolol succinate (Toprol) Bisoprolol (Zebeta)
What is the only Beta blocker used for HTN emergency and/or SVT? Esmolol (Breviblock)
What beta blockers are taken with food? Carvedilol (Coreg) Metoprolol (Lopressor) Propranolol (Inderal)
What is the only Beta blocker used for arrythmias? Sotalol (Betapace)
Can you use Bystolic for renal patients? Dose adjust if CrCl <30mL/min
What Beta Blockers can you use for patients with Asthma/COPD? Atenolol, Metoprolol, Esmolol, Bisoprolol, Betaxolol, Bystolic, Acebutolol
What Beta Blockers come in IV? Metoprolol, Atenolol, Labetalol, Esmolol, Propranolol
SE for Calcium Channel Blockers (CCB)? Flushing, Constipation, Bilateral Edema, Gingival Hyperplasia
Are CCB's substrates, inhibitors or inducers? Subtrate and Inhibitor
What is Nimodipine used for? Contraindicated in what allergy? Subarachonoid hemorrhage; soy & egg allergy
How long can you use Cleviprex after puncturing the stopper? 4 hours then discard
What are the indications for Nicardipine? Nicardipine SR = only for HTN. Cardene = angina, CHF
What CCB can be used for CHF? Nicardipine (Cardene) since it does not decrease myocardial contractility
What is the DoC for Prinzmetal angina and Reynaud's Phenomenon? Calcium Channel Blockers
Can you crush Plendil? No, because it is an extended release tablet
Can you cut Toprol XL? Yes, even if it's an extended release tab.
What is the indication for Nifedipine IR? Angina and Reynaud's
How do you give Captopril? BID/TID bec of its short half-life and on EMPTY stomach
What ACE Inh can you give to patients with renal failure? Moexipril (Univasc) Fosinopril (Monopril)
What are the contraindications for using ACE Inh? Renal failure (SCr >3mg/dL) Renal artery stenosis = Hyperkalemia Pregnancy Cat. D
What is the DoC for African-Americans? CCB and diuretics
ACE Inh is the DoC for what? DM, CHF, MI
What happens when a patient is taking both ACE Inh and Lithium? Lithium levels increase by 300% bec ACE Inh decreases levels of Na.
What is Tekturna? SE? Aliskiren, a direct renin inhibitor; diarrhea.
What is the dosing for Tekturna? 150mg or 300mg QD
Can you use Uroxatral for renal patients Alfuzosin has to be used with caution in patients with CrCl <30mL/min
Can you use Silodosin for renal patients? Silodosin (Rapaflo) 4mg daily with meals if CrCl = 30-50mL/min; don't use for CrCl <30mL/min
What is the other name for Cialis? Tadalafil (generic) Adcirca, 40mg for pulmonary HTN
What is Vardenafil? Levitra
What are the other names for Sildenafil? Viagra Revatio, 20mg TID for pulmonary HTN
What is Caverject? Dosing? Alprostadil for erectile dysfunction given as a 2.5mcg injection. Max: 60mcg no more than 3x QW.
What is Muse? Alprostadil pellet, no more than BID
Which alpha adrenergic blockers are also 3A4 substrates? Alfuzosin (Uroxatral) and Silodosin (Rapaflo)
What are the indications for Guanfacine? Tenex, for HTN Intuniv, for ADHD.
What is Aldomet? SE? Methyldopa SE: ***CALL Colitis Anemia Liver, Lupus
Major SE for Reserpine? Depression
What is Apresoline? Hydralazine
What is Loniten? Minoxidil; Rogaine, OTC for hair growth
What is Lotrel? Benazepril and Amlodipine
What is Exforge? Valsartan and Amlodipine
What is Lexxel? Enalapril and felodipine
What is Tarka? Trandolapril and Verapamil
What is Ziac? Bisoprolol and HCTZ
What is Azor? Amlodipine and Olmesartan
What is Twynsta? Telmisartan and Amlodipine
HTN medications used for pregnant patients? Hydralazine Labetalol Methyldopa Nifedipine
What are signs and sympoms of end organ damage present in HTN emergencies? Brain: severe HA/neuro S/S Heart: angina/shortness of breath/EKG changes Eyes: Papilledema/blurry vision Kidneys: major acute renal dysfunction
What's the goal BP reading when dealing with HTN emergency? Decrease BP by 10-15% or DPB 110
What are the drugs used for HTN urgencies? Captopril Labetalol Amlodipine Clonidine
What are the meds used for HTN emergency (IV drugs)? Sodium nitroprusside (Nipride, Nitropress) Cleviprex Labetalol Esmolol (Brevibloc), Enalapril Nitroglycerin,Nicardipine Fenoldopam(Corlopam) Phentolamine
What is the antidote for cyanide poisoning? Sodium nitrate + sodium thiosulfate
What forms does Hydralazine come in? Tabs, IV, IM
What are the therapuetic levels for Digoxin in CHF? 0.5 - 0.8 mg/mL
What are the therapeutic levels of Digoxin when treating arrythmias? 0.8 - 2.0 mg/mL
What drugs displace Digoxin? Verapamil Amiodarone Quinidine
Created by: oparaMK
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