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Epilepsy/Seizures

Brand/Generics plus toxicities

QuestionAnswer
phenytoin Dilantin
fosphenytoin Cerebyx
carbamazepine Tegretrol, Tegretrol XR, Carbatrol, Epitol
oxcarbazepine Trileptal
valproate or valproic acid Depakene, Stavzor
divalproex delayed release Depakote, Depakote ER
lamotrigine Lamictal, Lamictal ODT, Lamictal CD (chewable), Lamictal XR
ethosuximide Zarontin
topiramate Topamax
clonazepam Klonopin
levetiracetam Keppra, Keppra XR
zonisamide Zonegran
phenobarbital Luminal, Barbital
primidone Mysoline
tiagabine Gabitril
lacosamide Vimpat
pregabalibn Lyrica
vigabatrin Sabril
ezogabine Potiga
rufinamide Banzel
drugs that cause teratogenicity phenytoin, valproic acid (BBW), carbamazepine, topiramate
hepatotoxicity -FDA BBW valproic acid, felbamate
felbamate Felbatol
caution in patients with hepatic dysfxn phenobarbital, phenytoin, carbamazepine, valproic acid, tigabine
caution in patients with renal failure gabapentin, topiramate, pregabalin
significant congitive impairment phenytoin, phenobarbital, primidone, clonazepam
decrease effects of oral contraceptives felbamate, phenobarbital, phenytoin, carbamazepine, oxcarbamazepine
fatal pancreatitis- FDA BBW valproic acid
aplastic anemia - FDA BBW carbamazepine, felbamate
skin rash (SJS) phenobarbital, phenytoin, carbamazepine, oxcarbazepine, lamotrigine, valproic acid, zonisamide
oligohydrosis (inability to sweat leads to incr risk of stroke, highest in children) topiramate, zonisamide
nephrolithiasis topiramate, zonisamide
weight gain valproic acid
weight loss levetiracetam, topiramate, zonisamide, lamotrigine(?)
aseptic meningitis lamotrigine
Created by: jamcat
Popular Pharmacology sets

 

 



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