Save
Upgrade to remove ads
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Pharm II - Week 10

Reproductive Drugs Part 2

QuestionAnswer
True or false: androgens decline in 40s and only 1/2 amount exists by the time a man is 80 True
Primary androgen is ____ and has the following roles: Testosterone. Male sex characteristics, female libido/clitoris, increase skeletal muscle, synthesis of erythropoietin
Indication for Androgen: 1) Male hypogonadism (low T), 2) muscle wasting (AIDs), 3) female poor libido
Male hypogonadism has following issues Congenital, aging, ED, want to increase libido, looks, volume of ejaculate
Prototype for androgens: list patch and gel names Androderm, Androgel
Androgen administration: route, duration, frequency IM, long-acting, q2-4wk. Patch can be on upper arm, back, butt, abdm and done daily
ADE of androgen: Rash
Androgel advantages: Use daily, doesn't fall off, more consistent levels of hormone well absorbed
Androgel can be applid to upper arm, shoulders, abdm, but not __ Scrotum
With androgel, you should wait __ before showering and it can be transferred to others even after dried 5-6 hrs
Androgen AE include: Virilization, premature epiphyseal closure (teens), HEPATOTOXICITY (need SERIAL liver enzyme tests, short term use), worsen lipid panel, worsen/potentiate prostate cancer, edema, gynecomastia
Androgen is considered category __, therefore women should __ X, serial pg test
Androgen, when abused can lead to... Hypogonadism, rage
True or false: ED is often associated with chronic illness or its treatment (DMII, HTN, depression) True
__% of men 40-70 experience ED 50
Treatment for ED includes: Psychotherapy, surgery (implant), drugs (mostly po)
Prototype for PDESIs (enzyme inhibitor): Sildenafil/Viagra
How does Sildenafil/Viagra work? Inhibit an enzyme to maintain erection. Enhances response of erection but DOES NOT cause one!
PDESI: route, onset, half-life, metabolism PO, high-fat meals delay onset (2 hrs), half life: 4hrs, metabolized heavily in liver
True or false: sildenafil does little to change sexual arousal in women True
ADE of PDESIs/Viagra: Hypotension, Priapism (erection >4'), optic neuropathy, hearing loss
DDis/DFIs of viagra/sildenafil: CONTRAINDICATED WITH NITRATES. Caution with alpha blockers. Avoid grapefruit juice and erythromycin
Tadalafil/Cialis has __ duration 36 hr
True or false: Tadalafil/Cialis has same contraindications as Viagra/Sildeanfil True
BPH occurs in __% men by age 60 and __% men by age 85 50% by age 60, 90% by age 85
BPH can cause the following s/sx: Urinary urgency, dysuria, nocturia, straining to void, dribbling, UTI
BPH Tx: Surgery: transurethral resection for severe BPH. Drugs: moderate use. Watchful waiting is minimal
_____ is a category of drugs used to Tx BPH 5-Alpha-Reductase Inhibitors
Prototype of 5-Alpha-Reductase inhibitors is: Finasteride/Proscar
How does Finasteride/Proscar work? Inhibits conversion of testosterone --> DHT. Epithelial cells decrease in size and number. Works best with large prostates
True or false: Finasteride/Proscar affects testosterone levels False. Inhibits conversion without affecting testosterone
Finasteride/Proscar must be taken __ (route), and __ (frequency) for life PO, daily
Finasteride/Proscar may decrease risk for __ and decrease ___ Prostate cancer; prostate-specific antigen
ADE of finasteride/proscar is: decreased libido in 10% and gynecomastia
How long does it take for finasteride/Proscar to work? 6-12 months
Finasteride/Proscar can also be known as ___ when used to Tx this condition _____ Propecia; Tx male pattern baldness
Propecia takes __ to work 3 months
True or false: if one stops taking propecia, will lose the hair that grew in 12 months True
Created by: choel
Popular Pharmacology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards