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Anti-Psychotics

Mod 4

QuestionAnswer
CHLOROPROMAZINE Phenothiazine toxicity sedative and hypotension
THIORIDAZINE Phenothiazine Greatest antimuscurinic potency
FLUPHENAZINE Phenothiazine tardive dyskinesia
CHLOPROTHIXINE Non-phenothiazine Typical
HALOPERIDOL Non-phenothiazine Typical EPSEs least anti-muscurinic potency
CLOZAPINE Non-phenothiazine Atypical no EPSEs agranulocytosis
SERTINDOLE Non-phenothiazine Atypical
RISPERIDONE Non-phenothiazine Atypical no anticholinergic activity hypotension broad
MOLINDONE 2nd Gen Atypical Antipsychotic
LOXAPINE 2nd Gen Atypical Antipsychotic
OLANZAPINE 2nd Gen Atypical Antipsychotic weight gain short half-life
QUETINPINE 2nd Gen Atypical Antipsychotic sedative weight gain
ARIPIPRAZOLE 2nd Gen Atypical Antipsychotic little weight gain
ZIPRESIDONE 2nd Gen Atypical Antipsychotic little weight gain
Phenothiazines Properties D1 and D2 caudate and putamen
Non-Phenothiazines Typical D1 and D2 caudate and putamen
Non-Phenothiazines Atypical D3 and D4 accumbens, amygdala, cortex 5HT2a receptor antagonists - decrease DA in straitum
What is the pleasure center of the brain? mesolimbic and mesocortical pathways (tubular infundibular tract)
What are the huge advantage of Atypical Non-phenothiazines? no extrapyramidal motor side effects No tardive dyskinesia dont mess with motor function of brain
Created by: prinny916
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