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test 1-3
pht 101 test 1-3
| Question | Answer |
|---|---|
| When this drug is dispensed, a "Do not drink alcohol" sticker must be attached to the container of | metronidazole (Flagyl) |
| Which of the following drugs is classified as a macrolide? | erythromycin |
| What phase of clinical trials is carried out after the drug has been approved for marketing? | phase IV |
| What term is used to describe the study of drugs on living systems? | pharmacology |
| What does bioavailability reflect? | the fraction of an administered dose that is available to the target tissue |
| What is the study of the activity of drugs within the body known as? | pharmacokinetics |
| How do penicillins work? | They prevent bacteria from forming their rigid cell wall. |
| Which of the following antifungal drugs should be taken with a fatty meal and can be used safely in children? | griseofulvin (Fulvicin PIG) |
| Why might a dentist prescribe amoxicillin? | to provide prophylaxis for patients with endocarditis |
| How do third generation cephalosporins differ from earlier cephalosporins? | improved activity against gram negative bacteria |
| How does grapefruit juice interact with certain drugs? | It contains a compound that can inhibit intestinal cytochrome P 450, allowing more drug to be absorbed into the bloodstream. |
| What was the first true class of antibiotics? | sulfonamides |
| Bactrim | comes in SS, DS, liquid ( 200mg 40mg/5 ml) |
| Cipro | 500 mg po BID |
| Amoxicillin | 500 mg po TID |
| Zithromax | Take 2 tablets po now then 1 every day |
| What is the mechanism of action of quinolones? | They antagonize the enzyme responsible for coiling and replicating DNA. |
| Which of these is a brand name drug for a sulfonamide? | Bactrim |
| Which of the following anticonvulsants is a DEA scheduled controlled substance? | diazepam (Valium) |
| Which of the following is an OTC expectorant available in caplet, capsule, liquid, syrup, tablet, and sustained release forms? | guaifenesin (Mucinex) |
| What are the most common side effects of antiseizure medications? | sedation and some degradation of cognitive processes |
| What term is used to describe continuous tonic-clonic seizures, lasting over 30 minutes, during which consciousness may not return? | status epilepticus |
| What class of drugs may be used to treat migraine headaches? | triptans |
| What dopamine precursor is used to treat Parkinson patients? | levodopa (Dopar) |
| Which type of receptor increases the heart rate? | beta 1 receptors |
| Which of the following antianxiety drugs is not a benzodiazepine? | buspirone (BuSpar) |
| Which drug used to treat depression is also used for smoking cessation? | buproprion (Wellbutrin) |
| Why might a prescribing physician prefer donepezil (Aricept) over tacrine (Cognex) for Alzheimer's disease? | Donepezil is given once a day. |
| Which of the following antianxiety agents might a trembling bride and groom take prior to their wedding ceremony? | propranolol (Inderal) |
| What combination drug contains levodopa plus an inhibitor of peripheral levodopa metabolism? | Sinemet |
| alprazolam | 0.5 mg |
| zolpidem | 10 mg |
| buproprion | 150 mg |
| fentanyl | 50 mcg/hr |
| Which of the following drugs is only indicated for long term maintenance therapy of bronchospasms associated with emphysema and bronchitis? | tiotropium (Spiriva) |
| Which respiratory medication listed below is an inhaled corticosteroid? | fluticasone (Flonase, Flovent) |
| Which class of diuretics should be prescribed with caution to patients on ACE inhibitors? | potassium sparing |
| Which of the following drugs reduces cholesterol levels by inhibiting HMG CoA reductase, the enzyme that catalyzes the rate limiting step in the synthesis of cholesterol? | simvastatin (Zocor) |
| Which of the following drug classes is not used to treat angina? | angiotensin II receptor antagonists |
| digoxin | 0.125 mg |
| furosemide | 40 mg |
| naproxen | 375 mg |
| metformin | 1000 mg |
| What class of drugs is commonly used to treat benign prostatic hyperplasia (BPH)? | alpha adrenergic blockers |
| Which of the following drugs is an inhibitor of angiotensin converting enzyme and is used to treat congestive heart failure and hypertension? | lisinopril (Prinivil, Zestril) |
| Which of the following antihypertensive drugs binds to angiotensin II receptors and rarely causes coughing as an adverse effect? | valsartan (Diovan) |