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chpt 16 quiz
pht 101 c16
| Question | Answer |
|---|---|
| 1 what statement regarding hydrogen peroxide is correct? | it's cleansing action results from the oxygen produced |
| 2 what monoclonal antibody shrinks colorectal tumors, although it has not been shown to extend life? | cetuximab (Erbitux) |
| 3 what class of chemotherapeutic drugs binds irreversible cross links in DNA so that the DNA & cells can't reproduce? | alkylating agents |
| 4 what term describes tumors that have detatched & relocated to form tumors in other parts of the body? | metastatic tumors |
| 5 what is characteristic of malignancies? | a & b (abnormal, fatal, uncontrolled growth that threatens normal body functions & cells lose contact inhibition, preventing cell division getting crowded together in tissue/organs) |
| 6 for the monoclonal antibody abcixmab, what do the last 3 letters (mab) mean? | monoclonal anti body |
| 7 what study type has shown positive pharmacoeconomic outcomes of using recombinant DNA products? | cost utility ratio |
| 8 what chemotherapeutic agent is made of amino acid sequence from diphtheria toxin plus sequence from interleukin 2? | denileukin diftitox (ONTAK) |
| 9 which of the following drugs is a colony stimulating factor (CSF)? | epoetin alpha (Epogen, Procrit) |
| 10 what drug class does alteplase (Activase) belong to? | tissue plasminogen activator (PA) |
| 11 which interferon is an example of biologic response modifier? | both ( interferon beta 1b (Betaseron) & interferon beta 1a (Avonex, Rebif) |
| 12 what recombinant DNA agent increases red blood cell production? | epoetin alpha (Epogen, Procrit) |
| 13 which drug is an estrogen receptor antagonist? | a & b (fluvestrant (Faslodex) and tamoxifen (Nolvadex)) |
| 14 what term describes the process where RNA is made from DNA to serve as a messenger? | transcription |
| 15 what drug is equal to granulocyte colony stimulating factor (G CSF)? | filgrastim (Neupogen) |
| 16 which is not a lymphoid organ? | liver |
| 17 what is in "magic swizzle" ? | lidocaine, diphenhydramine, & Maalox |
| 18 when preping which drug should patients just use glass droppers & glass containers? | cyclosporine (Sandimmune) |
| 19 what sympathomimetic drug is used to counter the bronchoconstriction & hypotesion associated with an anaphylactic reaction? | epinephrine |
| 20 what chemotherapeutic agent is used to treat Hodgkin disease? | procarbazine (Matulane) |
| 21 what is attached to filgrastim th form the longer acting pegfilgrastim (Neulasta)? | polyethylene glycol |
| 22 what is a characteristic of plasmids? | A, B, & C (they're in bacteria, they transfer resistance to antibiotics between bacterial cells, & they move freely between bacterial cells) |
| 23 what is the product reverse trascriptase acting on RNA? | cDNA |
| 24 which of the following is a reticuloendothelial system cell? | all (histocyte, kupffer, monocyte, & microglia) |
| 25 what term describes a drug that prevents destruction of healthy cells during treatment with a chemotherapeutic agent? | cytoprotective agent |
| 26 which is an example of a type 4 delayed reaction? | contact dermatitis |
| 27 what control signal must be added to DNA to assure the start of protein sythesis in a recombinant process? | promoter |
| 28 serum sickness is an example of what type of allergy? | type 3 toxin precipitin |
| 29 which interferon is correctly paired with the cell in which it is produced? | all (alpha to leukocytes, beta to connective tissue cells, & gamma to T lymphocytes) |
| 30 what adverse effect of chemotherapy may be treated with aprepitant (Emend)? | nausea & vomiting |
| 31 which hormone is correctly paired with the type of cancer that it treats? | triptorelin (Trelstar) to prostate |
| 32 with what type of immunity is there a specific response to antigen? | cellular immunity |
| 33 what 3 steps are necessary to produce a protein? | replication, transcription, & translation |
| 34 what aspect of a protein determines it's biologic activity? | 3D shape of a twisted chain of amino acids |
| 35 what's the most common immunoglobulin? | IgG |
| 36 which antirejection drug below is also used for rheumatoid arthritis? | azathioprine (Imuran) |
| 37 which drug is used to treat nausea & vomiting resulting from chemotherapy? | all (granisetron (Kytril), odansetron (Zofran), & palonosetron (Aloxi)) |
| 38 which drug (for breast cancer recurrence prevention), blocks the enzyme aromatase? | all (anastrozole (Arimidez), exemestane (Aromasin), & letrozole (Femara)) |
| 39 what is an immune system cell example? | both (B cell & macrophage) |
| 40 which tissue is not part of the lymphatic system? | liver |
| 41 Which drug shouldn't be used by pregnant patients because of (ovarian cancer)? | Taxol |
| what drug has the national cancer institute recommend oncologist to prescribe no more than 5 yrs.? | tamoxofen |
| what describes chemotherapy goal? | remission |
| Vitamin K is | the antidote for warferin |
| Folic acid is mainly for | pregnant women who need blood cell production. |
Created by:
cindya
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